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CNRIP1
HPA
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  • CNRIP1
PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

CNRIP1
Synonyms C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924
Gene descriptioni

Full gene name according to HGNC.

Cannabinoid receptor interacting protein 1
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 2
Cytoband p14
Chromosome location (bp) 68284171 - 68320051
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

3
Ensembl ENSG00000119865 (version 109)
Entrez gene 25927
HGNC HGNC:24546
UniProt Q96F85 (UniProt - Evidence at protein level)
neXtProt NX_Q96F85
GeneCards CNRIP1
Antibodypedia CNRIP1 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

[Isoform 1]: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.... show less
Gene summary (Entrez)i

Useful information about the gene from Entrez

This gene encodes a protein that interacts with the C-terminal tail of cannabinoid receptor 1. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
CNRIP1-201
ENSP00000263655
ENST00000263655
Q96F85
[Direct mapping] CB1 cannabinoid receptor-interacting protein 1
Show all
   DeepTMHMM predicted secreted proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0008022 [protein C-terminus binding]
GO:0031718 [type 1 cannabinoid receptor binding]
GO:2000272 [negative regulation of signaling receptor activity]
Show all
164 aa
18.6 kDa
No 0
CNRIP1-202
ENSP00000386883
ENST00000409559
Q96F85
[Direct mapping] CB1 cannabinoid receptor-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005886 [plasma membrane]
GO:0008022 [protein C-terminus binding]
GO:0010469 [regulation of signaling receptor activity]
GO:0031718 [type 1 cannabinoid receptor binding]
GO:2000272 [negative regulation of signaling receptor activity]
Show all
128 aa
14.2 kDa
No 0
CNRIP1-203
ENSP00000386544
ENST00000409862
B8ZZB8
[Direct mapping] CB1 cannabinoid receptor-interacting protein 1
Show all
   DeepTMHMM predicted secreted proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
137 aa
15.2 kDa
No 0

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