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MXI1
HPA
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  • TISSUE
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  • MXI1
PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

MXI1
Synonyms bHLHc11, MAD2, MXD2, MXI
Gene descriptioni

Full gene name according to HGNC.

MAX interactor 1, dimerization protein
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Cancer-related genes
Disease related genes
Human disease related genes
Transcription factors
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 10
Cytoband q25.2
Chromosome location (bp) 110207605 - 110287365
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

26
Ensembl ENSG00000119950 (version 109)
Entrez gene 4601
HGNC HGNC:7534
UniProt P50539 (UniProt - Evidence at protein level)
neXtProt NX_P50539
GeneCards MXI1
Antibodypedia MXI1 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX.... show less
Molecular function (UniProt)i

Keywords assigned by UniProt to proteins due to their particular molecular function.

DNA-binding, Repressor
Biological process (UniProt)i

Keywords assigned by UniProt to proteins because they are involved in a particular biological process.

Transcription, Transcription regulation
Gene summary (Entrez)i

Useful information about the gene from Entrez

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
MXI1-201
ENSP00000239007
ENST00000239007
P50539
[Direct mapping] Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
228 aa
26.1 kDa
No 0
MXI1-202
ENSP00000331152
ENST00000332674
P50539
[Direct mapping] Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
295 aa
32.8 kDa
No 0
MXI1-203
ENSP00000354606
ENST00000361248
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3X5
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
182 aa
20.6 kDa
No 0
MXI1-204
ENSP00000358625
ENST00000369612
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-205
ENSP00000376842
ENST00000393134
B1ANN8
[Direct mapping] Max-interacting protein 1; cDNA FLJ61042, highly similar to MAX-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Cancers
   Cancers of male genital organs
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0046983 [protein dimerization activity]
Show all
218 aa
24.9 kDa
No 0
MXI1-206
ENSP00000407711
ENST00000442296
F6WCI9
[Direct mapping] Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Cancers
   Cancers of male genital organs
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0046983 [protein dimerization activity]
Show all
118 aa
13.8 kDa
No 0
MXI1-207
ENSP00000398981
ENST00000453116
F6U3F6
[Direct mapping] Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Cancers
   Cancers of male genital organs
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0046983 [protein dimerization activity]
Show all
226 aa
25.3 kDa
No 0
MXI1-211
ENSP00000498900
ENST00000650644
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-212
ENSP00000499158
ENST00000650696
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-214
ENSP00000498390
ENST00000650810
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-215
ENSP00000498547
ENST00000650843
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-217
ENSP00000499161
ENST00000650952
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-218
ENSP00000498396
ENST00000651004
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-220
ENSP00000498951
ENST00000651112
A0A494C1C1
[Direct mapping] Max-interacting protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Cancers
   Cancers of male genital organs
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0046983 [protein dimerization activity]
Show all
116 aa
13.6 kDa
No 0
MXI1-221
ENSP00000498764
ENST00000651167
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-224
ENSP00000499128
ENST00000651467
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-225
ENSP00000498536
ENST00000651495
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-226
ENSP00000498873
ENST00000651516
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-228
ENSP00000498554
ENST00000651613
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-229
ENSP00000498472
ENST00000651811
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-230
ENSP00000498238
ENST00000651848
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-231
ENSP00000498306
ENST00000651866
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-232
ENSP00000498928
ENST00000652028
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-235
ENSP00000499087
ENST00000652463
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-236
ENSP00000498573
ENST00000652506
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3Y0
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 3
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
192 aa
21.8 kDa
No 0
MXI1-237
ENSP00000498971
ENST00000652604
P50539
[Direct mapping] Max-interacting protein 1
Show all
A0A0S2Z3X5
[Target identity:100%; Query identity:100%] MAX interactor 1 isoform 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Transcription factors
   Basic domains
Cancer-related genes
   Candidate cancer biomarkers
Disease related genes
Human disease related genes
   Cancers
   Cancers of male genital organs
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000785 [chromatin]
GO:0000977 [RNA polymerase II transcription regulatory region sequence-specific DNA binding]
GO:0000978 [RNA polymerase II cis-regulatory region sequence-specific DNA binding]
GO:0000981 [DNA-binding transcription factor activity, RNA polymerase II-specific]
GO:0001227 [DNA-binding transcription repressor activity, RNA polymerase II-specific]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0046983 [protein dimerization activity]
GO:0090575 [RNA polymerase II transcription regulator complex]
Show all
182 aa
20.6 kDa
No 0

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