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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:6.7 nTPM
HPA Brain:43.9 nTPM
GTEx:6.7 nTPM
FANTOM5:16.2 Scaled Tags Per Million
Pig:58.6 nTPM
Mouse:25.5 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

43.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 39.4
2586 Male, age 75, left hemisphere 42.3
1827 Male, age 72, unknown 40.6
2219 Male, age 76, both hemispheres 40.6
1870 Female, age 42, unknown 39.8
2828 Female, age 72, unknown 39.4
2019 Male, age 18, unknown 39.3
1833 Male, age 53, unknown 38.6
2411 Female, age 72, unknown 38.4
1830 Male, age 51, unknown 37.9
2666 Male, age 74, left hemisphere 37.5
Dorsal raphe nucleus
nTPM: 36.8
2750 Male, age 76, both hemispheres 39.0
2047 Male, age 72, unknown 38.0
2016 Female, age 72, unknown 37.1
1828 Male, age 53, unknown 36.1
2298 Female, age 72, unknown 33.9
Inferior colliculus
nTPM: 38.3
1890 Male, age 53, unknown 40.1
2097 Female, age 72, unknown 39.4
1848 Female, age 42, unknown 38.4
2849 Male, age 72, unknown 35.1
Median raphe nucleus
nTPM: 38.4
2220 Male, age 76, midline 38.4
Periaquaductal grey, anterior
nTPM: 43.9
2502 Female, age 75, unknown 46.3
1947 Male, age 18, unknown 44.7
1795 Male, age 51, unknown 40.7
Periaquaductal grey, dorsal
nTPM: 37.6
1831 Male, age 72, unknown 38.5
1840 Male, age 53, unknown 38.3
2464 Female, age 72, unknown 36.8
2850 Male, age 76, both hemispheres 36.7
Periaquaductal grey, lateral
nTPM: 33.9
2053 Male, age 18, unknown 37.8
2140 Male, age 76, both hemispheres 32.3
2272 Male, age 74, both hemispheres 31.8
Pretectal area
nTPM: 43.3
1944 Female, age 72, unknown 51.9
1817 Female, age 42, unknown 51.8
1816 Male, age 51, unknown 50.1
2007 Male, age 72, unknown 50.0
1815 Male, age 53, unknown 45.5
2407 Male, age 75, both hemispheres 40.2
2667 Female, age 75, unknown 40.0
2825 Male, age 18, unknown 40.0
2224 Female, age 72, unknown 36.7
2316 Male, age 76, right hemisphere 36.4
2273 Male, age 74, both hemispheres 33.2
Red nucleus
nTPM: 38.3
2584 Male, age 75, left hemisphere 43.4
1821 Female, age 72, unknown 42.1
2785 Male, age 18, unknown 41.3
2503 Female, age 72, unknown 40.5
1865 Male, age 51, unknown 40.3
2725 Female, age 75, unknown 39.7
1954 Female, age 42, unknown 38.2
1904 Male, age 53, unknown 37.7
2823 Male, age 76, right hemisphere 37.1
2227 Male, age 72, unknown 33.5
2769 Male, age 72, unknown 33.3
2588 Male, age 74, left hemisphere 32.9
Substantia nigra
nTPM: 37.4
1889 Female, age 72, unknown 43.3
1916 Female, age 42, unknown 40.2
2241 Male, age 72, unknown 39.8
1941 Male, age 53, unknown 39.1
2583 Male, age 75, right hemisphere 38.0
2665 Male, age 74, both hemispheres 37.4
1851 Male, age 51, unknown 35.7
2409 Female, age 72, unknown 35.6
2590 Female, age 75, unknown 35.2
2699 Male, age 18, unknown 29.7
Superior colliculus
nTPM: 40.8
2261 Male, age 18, unknown 44.4
2664 Male, age 75, both hemispheres 44.2
1995 Male, age 72, unknown 42.4
2087 Female, age 72, unknown 42.0
2668 Female, age 75, unknown 41.9
1913 Female, age 42, unknown 41.3
1895 Male, age 76, right hemisphere 38.8
1796 Male, age 53, unknown 38.7
2587 Male, age 74, left hemisphere 37.4
1839 Male, age 51, unknown 36.9
Ventral tegmental area
nTPM: 36.6
2223 Female, age 72, unknown 39.2
1942 Male, age 51, unknown 38.1
2218 Male, age 76, both hemispheres 38.1
2410 Female, age 72, unknown 37.1
2021 Male, age 53, unknown 33.8
1915 Female, age 42, unknown 33.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 6.7
Samples: 139

Max nTPM: 9.5
Min nTPM: 3.4
Std nTPM: 1.1
Median nTPM: 6.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 9.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 9.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 9.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 8.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 8.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 8.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 8.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 8.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 8.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 8.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 8.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 8.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 8.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 8.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 8.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 8.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 8.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 8.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 8.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 8.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 8.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 7.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 7.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 7.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 7.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 7.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 7.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 7.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 7.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 7.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 7.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 7.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 7.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 7.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 7.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 7.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 7.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 7.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 7.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 7.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 7.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 7.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 7.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 7.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 7.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 7.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 7.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 7.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 7.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 7.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 7.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 7.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 7.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 7.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 7.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 7.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 6.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 6.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 6.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 6.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 6.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 6.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 6.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 6.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 6.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 6.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 6.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 6.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 6.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 6.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 6.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 6.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 6.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 6.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 6.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 6.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 6.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 6.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 6.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 6.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 6.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 6.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 6.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 6.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 6.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 6.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 6.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 6.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 6.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 6.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 6.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 6.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 6.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 6.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 6.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 6.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 6.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 6.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 6.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 5.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 5.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 5.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 5.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 5.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 5.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 5.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 5.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 5.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 5.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 5.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 5.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 5.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 5.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 5.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 5.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 5.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 5.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 5.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 5.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 5.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 5.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 5.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 5.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 5.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 5.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 5.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 5.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 5.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 5.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 5.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 5.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 4.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 4.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 4.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 4.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 4.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 4.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 3.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

16.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 16.2
FF:10158-103A5 76 years, female 16.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

58.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 47.7
Samples: 4

Max nTPM: 55.7
Min nTPM: 39.6
Sample A Female 55.7
Sample B Female 39.6
Sample C Male 49.6
Sample D Male 45.7
Midbrain
nTPM: 58.6
Samples: 4

Max nTPM: 81.4
Min nTPM: 42.9
Sample A Female 81.4
Sample B Female 50.7
Sample C Male 59.3
Sample D Male 42.9
Periaqueductal gray
nTPM: 40.9
Samples: 3

Max nTPM: 41.7
Min nTPM: 39.5
Sample B Female 41.5
Sample C Male 41.7
Sample D Male 39.5
Superior colliculi
nTPM: 42.5
Samples: 4

Max nTPM: 49.7
Min nTPM: 31.7
Sample A Female 43.7
Sample B Female 31.7
Sample C Male 49.7
Sample D Male 44.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

25.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 25.5
Samples: 4

Max nTPM: 26.6
Min nTPM: 24.4
Sample A Male 24.4
Sample B Male 26.6
Sample C Female 25.4
Sample D Female 25.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
68161467 Antisense, RP_041122_01_D08, Mouse strain C57BL/6J (56 days, male) 0.4

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