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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
224.4
nTPM
HPA:
224.4
nTPM
GTEx:
24.4
nTPM
FANTOM5:
160.2
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA025736
Antibody HPA025765
Antibody HPA025811
Antibody CAB021106
Cholangiocytes
Low
Low
Not detected
Not detected
Hepatocytes
Medium
Medium
Medium
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
224.4
Female, age 60
Liver sample 21 nTPM: 107.6
Male, age 54
Liver sample 23 nTPM: 133
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 280.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 289.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 154.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 218
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 624.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 140.2
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 84.4
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 212.3
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
24.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 24.4
Samples: 226
Max nTPM: 204.3
Min nTPM: 3.0
Std nTPM: 23.3
Median nTPM: 19.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
204.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
187.8
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
101.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
83.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
80.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
79.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
74.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
74.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
71.4
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
68.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
65.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
64.1
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
63.0
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
62.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
62.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
54.5
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
52.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
51.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
51.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
50.9
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
49.8
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
49.4
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
45.6
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
45.2
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
44.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
41.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
41.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
41.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
41.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
41.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
40.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
40.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
40.2
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
39.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
39.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
38.4
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
37.8
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
37.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
36.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
36.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
36.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
35.8
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
35.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
34.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
33.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
33.0
GTEX-17HHE-0126-SM-79398
50-59 years, male
32.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
32.1
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
30.2
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
30.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
30.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
29.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
29.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
28.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
28.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
28.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
28.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
27.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
27.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
27.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
26.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
26.6
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
26.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
26.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
26.2
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
25.3
GTEX-14JG1-1626-SM-664NH
40-49 years, male
25.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
24.8
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
24.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
24.7
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
24.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
24.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
24.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
23.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
23.6
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
23.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
23.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
23.4
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
23.1
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
23.1
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
23.0
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
22.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
22.9
GTEX-13113-1326-SM-5GCOI
60-69 years, female
22.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
22.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
22.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
22.2
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
22.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
21.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
21.6
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
21.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
21.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
21.2
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
21.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
20.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
20.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
20.8
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
20.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
20.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
20.6
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
20.6
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
20.5
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
20.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
20.2
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
20.1
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
20.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
19.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
19.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
19.7
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
19.4
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
19.3
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
19.3
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
19.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
18.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
18.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
18.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
18.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
17.9
GTEX-17F96-1226-SM-79OK2
70-79 years, male
17.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
17.5
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
17.3
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
17.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
17.1
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
17.0
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
16.9
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
16.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
16.6
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
16.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
16.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
16.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
16.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
16.2
GTEX-18465-1626-SM-7LG6N
50-59 years, male
16.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
15.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
15.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
15.8
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
15.6
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
15.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
15.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
15.1
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
15.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
15.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
14.9
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
14.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
14.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
14.7
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
14.7
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
14.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
14.2
GTEX-YECK-1926-SM-4W21H
60-69 years, male
14.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
13.8
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
13.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
13.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
13.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
13.4
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
13.2
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
13.1
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
13.1
GTEX-REY6-1226-SM-48FDR
60-69 years, male
13.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
12.8
GTEX-Q734-0326-SM-48U15
40-49 years, female
12.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
12.7
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
12.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
12.6
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
12.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
12.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
12.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
12.1
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
12.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
11.8
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
11.7
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
11.2
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
11.1
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
10.9
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
10.7
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
10.6
GTEX-13112-1426-SM-5EGH8
50-59 years, male
10.5
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
10.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
10.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
9.9
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
9.9
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
9.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
9.7
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
9.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
9.5
GTEX-RU72-1426-SM-46MUF
50-59 years, female
9.5
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
9.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
9.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
9.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
9.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
8.9
GTEX-12696-0826-SM-5EGGE
60-69 years, male
8.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
8.9
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
8.7
GTEX-S33H-1626-SM-4AD68
30-39 years, male
8.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
8.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
8.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
8.1
GTEX-QEL4-1226-SM-447A4
50-59 years, male
8.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
8.0
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
7.9
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
7.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
7.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
7.2
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
7.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
6.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
6.7
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
6.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
6.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
6.5
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
6.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
5.8
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
5.7
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
5.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
5.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
5.4
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
5.3
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
5.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
5.2
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
5.0
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
4.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
4.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
4.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
3.2
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
3.2
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
3.0
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
