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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
95.5
nTPM
HPA:
93.0
nTPM
GTEx:
95.5
nTPM
FANTOM5:
133.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA027337
Antibody HPA031082
Antibody CAB017460
Cholangiocytes
Low
Low
Not detected
Hepatocytes
Low
Medium
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
93.0
Female, age 60
Liver sample 21 nTPM: 76.6
Male, age 54
Liver sample 23 nTPM: 87
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 78.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 106.9
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 108.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 99.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 95
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 85.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 87.7
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 105.3
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
95.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 95.5
Samples: 226
Max nTPM: 281.5
Min nTPM: 33.7
Std nTPM: 39.4
Median nTPM: 87.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
281.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
277.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
264.6
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
220.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
216.4
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
206.8
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
193.5
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
173.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
169.2
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
159.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
158.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
155.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
153.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
151.9
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
151.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
147.4
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
146.5
GTEX-QEL4-1226-SM-447A4
50-59 years, male
146.0
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
145.1
GTEX-O5YV-0726-SM-EV798
60-69 years, female
145.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
145.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
144.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
144.1
GTEX-S32W-1926-SM-4AD63
50-59 years, female
141.3
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
139.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
139.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
138.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
136.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
135.7
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
135.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
133.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
133.3
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
132.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
132.5
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
131.2
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
130.9
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
128.9
GTEX-P78B-1326-SM-3P611
40-49 years, female
128.5
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
128.4
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
128.3
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
126.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
126.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
125.7
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
124.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
123.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
123.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
121.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
121.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
120.6
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
119.8
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
116.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
116.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
116.1
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
115.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
115.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
114.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
114.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
114.5
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
113.8
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
113.7
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
113.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
113.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
111.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
110.9
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
110.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
110.4
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
110.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
109.8
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
109.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
109.3
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
109.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
108.9
GTEX-12696-0826-SM-5EGGE
60-69 years, male
108.2
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
107.2
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
106.7
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
106.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
105.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
104.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
103.7
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
103.4
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
100.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
100.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
99.9
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
98.8
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
98.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
98.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
98.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
98.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
96.9
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
95.7
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
95.5
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
95.3
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
94.1
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
94.0
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
93.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
93.7
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
93.6
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
93.5
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
93.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
92.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
92.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
92.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
92.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
91.9
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
91.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
90.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
90.8
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
90.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
90.7
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
88.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
88.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
87.4
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
87.1
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
87.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
86.4
GTEX-17HHE-0126-SM-79398
50-59 years, male
86.4
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
85.9
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
85.8
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
85.4
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
85.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
84.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
84.0
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
83.9
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
83.9
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
83.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
83.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
83.3
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
83.1
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
82.7
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
82.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
81.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
81.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
80.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
80.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
77.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
77.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
77.3
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
77.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
76.9
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
76.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
76.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
76.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
76.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
76.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
75.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
74.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
74.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
73.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
73.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
73.2
GTEX-REY6-1226-SM-48FDR
60-69 years, male
73.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
72.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
72.4
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
72.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
72.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
71.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
71.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
71.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
70.9
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
70.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
70.3
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
69.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
69.2
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
68.8
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
68.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
67.4
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
67.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
67.1
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
66.2
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
66.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
65.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
65.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
65.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
65.2
GTEX-144GL-1426-SM-79OMA
50-59 years, male
64.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
64.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
64.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
64.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
63.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
63.5
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
63.5
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
63.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
62.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
62.6
GTEX-13112-1426-SM-5EGH8
50-59 years, male
62.4
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
62.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
62.1
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
62.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
61.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
60.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
60.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
60.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
60.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
60.0
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
59.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
59.8
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
59.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
59.1
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
58.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
58.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
57.9
GTEX-1B933-1226-SM-731DW
50-59 years, female
57.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
57.3
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
56.5
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
54.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
53.9
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
53.7
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
53.6
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
53.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
53.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
52.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
52.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
51.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
51.2
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
50.7
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
50.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
50.4
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
49.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
49.4
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
49.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
49.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
47.9
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
47.6
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
45.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
37.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
33.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
