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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
145.2
nTPM
HPA:
145.2
nTPM
GTEx:
120.4
nTPM
FANTOM5:
692.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody CAB019427
Cholangiocytes
Low
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
145.2
Female, age 60
Liver sample 21 nTPM: 217.9
Male, age 54
Liver sample 23 nTPM: 395.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 307.2
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 62
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 29.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 97.8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 58.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 99.2
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 156.8
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 27.5
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
120.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 120.4
Samples: 226
Max nTPM: 823.8
Min nTPM: 4.4
Std nTPM: 151.4
Median nTPM: 70.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
823.8
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
799.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
751.4
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
702.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
689.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
655.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
579.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
514.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
511.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
480.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
450.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
447.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
432.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
417.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
397.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
397.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
396.5
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
390.8
GTEX-13113-1326-SM-5GCOI
60-69 years, female
368.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
334.8
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
333.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
316.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
307.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
301.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
293.4
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
279.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
277.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
273.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
255.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
243.3
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
230.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
225.1
GTEX-13112-1426-SM-5EGH8
50-59 years, male
222.3
GTEX-14PHX-0526-SM-664NW
50-59 years, male
219.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
217.5
GTEX-REY6-1226-SM-48FDR
60-69 years, male
205.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
199.5
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
193.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
190.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
189.6
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
188.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
181.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
181.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
177.4
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
173.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
173.3
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
165.6
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
162.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
160.4
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
154.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
154.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
151.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
150.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
150.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
150.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
150.3
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
148.9
GTEX-O5YV-0726-SM-EV798
60-69 years, female
145.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
141.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
140.4
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
138.0
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
136.8
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
135.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
131.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
130.5
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
126.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
126.1
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
118.1
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
117.2
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
116.5
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
116.2
GTEX-14E7W-1526-SM-6871X
70-79 years, male
112.9
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
112.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
110.9
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
110.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
110.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
109.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
109.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
106.7
GTEX-1399T-0826-SM-5IFES
60-69 years, male
106.6
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
105.6
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
102.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
102.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
100.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
97.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
97.4
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
97.0
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
94.1
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
91.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
90.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
89.6
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
89.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
88.6
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
88.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
87.3
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
86.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
86.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
85.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
82.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
80.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
80.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
80.2
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
79.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
77.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
76.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
76.1
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
76.1
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
75.1
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
75.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
73.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
73.2
GTEX-14JG1-1626-SM-664NH
40-49 years, male
70.4
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
70.3
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
69.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
67.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
64.8
GTEX-144GL-1426-SM-79OMA
50-59 years, male
63.5
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
59.3
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
58.5
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
57.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
56.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
55.7
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
54.9
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
53.6
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
53.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
52.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
52.0
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
51.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
51.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
49.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
48.8
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
48.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
48.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
45.0
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
44.8
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
42.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
42.7
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
40.7
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
40.3
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
39.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
39.9
GTEX-YECK-1926-SM-4W21H
60-69 years, male
39.2
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
39.0
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
38.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
38.8
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
38.4
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
38.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
37.4
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
36.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
36.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
35.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
35.6
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
34.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
33.3
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
33.0
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
33.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
32.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
32.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
32.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
32.1
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
31.7
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
31.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
30.7
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
30.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
29.5
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
28.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
28.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
27.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
27.6
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
26.3
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
26.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
25.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
25.4
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
25.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
24.5
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
23.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
23.5
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
23.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
23.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
23.2
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
20.9
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
20.7
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
20.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
20.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
20.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
19.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
19.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
19.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
18.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
18.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
18.2
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
18.0
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
17.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
17.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
17.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
17.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
15.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
15.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
15.4
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
14.8
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
14.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
14.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
13.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
13.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
13.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
13.0
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
12.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
11.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
11.0
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
10.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
10.8
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
10.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
9.9
GTEX-12696-0826-SM-5EGGE
60-69 years, male
9.6
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
9.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
9.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
8.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
8.8
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
7.8
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
7.4
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
7.3
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
7.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
6.6
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
4.6
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
4.4
GTEX-17HHE-0126-SM-79398
50-59 years, male
4.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
