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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
High
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
61.2
nTPM
HPA:
38.0
nTPM
GTEx:
61.2
nTPM
FANTOM5:
75.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA037577
Cholangiocytes
High
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
38.0
Female, age 60
Liver sample 21 nTPM: 28.9
Male, age 54
Liver sample 23 nTPM: 27.1
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 30.5
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 42.1
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 36.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 30.3
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 39.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 65.2
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 23.8
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 56.9
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
61.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 61.2
Samples: 226
Max nTPM: 190.9
Min nTPM: 13.8
Std nTPM: 30.4
Median nTPM: 55.9
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
190.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
145.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
144.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
140.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
139.1
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
138.1
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
135.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
135.0
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
131.7
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
125.8
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
125.4
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
123.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
119.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
116.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
113.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
113.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
110.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
109.8
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
109.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
105.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
101.9
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
101.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
99.4
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
98.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
98.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
98.5
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
98.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
98.0
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
96.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
96.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
94.4
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
94.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
93.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
92.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
91.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
91.6
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
90.3
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
90.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
89.4
GTEX-QESD-2026-SM-447BI
20-29 years, male
89.0
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
88.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
88.3
GTEX-14JG1-1626-SM-664NH
40-49 years, male
88.0
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
87.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
87.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
86.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
85.9
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
85.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
84.9
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
84.2
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
83.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
83.7
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
83.6
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
83.3
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
80.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
80.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
80.4
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
80.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
80.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
79.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
78.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
78.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
75.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
74.4
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
73.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
71.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
71.3
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
70.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
70.1
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
69.6
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
69.3
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
68.5
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
67.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
67.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
67.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
67.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
67.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
66.8
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
66.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
66.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
65.5
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
65.0
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
64.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
64.3
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
64.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
63.2
GTEX-14PHX-0526-SM-664NW
50-59 years, male
63.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
62.8
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
62.4
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
62.1
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
61.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
61.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
61.6
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
61.4
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
61.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
60.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
60.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
60.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
60.1
GTEX-1B933-1226-SM-731DW
50-59 years, female
59.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
59.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
58.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
57.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
57.7
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
57.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
57.4
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
57.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
56.8
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
56.7
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
56.6
GTEX-13112-1426-SM-5EGH8
50-59 years, male
56.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
56.2
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
56.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
55.8
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
55.3
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
55.3
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
54.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
54.8
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
53.1
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
52.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
52.5
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
52.4
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
52.3
GTEX-11GSP-0626-SM-5986T
60-69 years, female
52.1
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
52.1
GTEX-11ZUS-2526-SM-59872
30-39 years, male
52.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
51.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
51.0
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
50.7
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
50.6
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
50.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
49.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
49.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
49.4
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
49.3
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
49.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
48.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
48.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
48.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
48.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
47.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
47.7
GTEX-14E7W-1526-SM-6871X
70-79 years, male
47.1
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
46.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
45.4
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
45.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
45.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
44.9
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
44.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
44.5
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
44.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
44.0
GTEX-P78B-1326-SM-3P611
40-49 years, female
43.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
43.6
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
43.4
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
43.0
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
42.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
42.7
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
42.7
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
42.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
41.5
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
41.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
40.8
GTEX-Q734-0326-SM-48U15
40-49 years, female
40.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
38.9
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
38.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
37.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
37.9
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
37.7
GTEX-18A66-2026-SM-7189C
60-69 years, male
37.5
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
37.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
36.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
36.0
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
35.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
35.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
35.1
GTEX-14XAO-0226-SM-68728
60-69 years, female
34.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
34.8
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
34.3
GTEX-S33H-1626-SM-4AD68
30-39 years, male
33.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
33.8
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
33.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
33.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
33.1
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
32.9
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
32.8
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
32.6
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
32.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
32.3
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
32.3
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
31.8
GTEX-R53T-0326-SM-48FEC
50-59 years, female
31.7
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
31.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
30.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
30.6
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
29.8
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
29.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
29.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
29.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
28.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
28.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
27.5
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
27.4
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
27.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
27.0
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
26.9
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
26.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
26.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
26.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
26.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
25.7
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
25.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
24.5
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
24.5
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
24.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
24.0
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
23.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
23.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
22.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
21.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
20.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
20.1
GTEX-S32W-1926-SM-4AD63
50-59 years, female
19.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
15.0
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
14.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
13.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
