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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:59.4 nTPM
HPA Brain:148.5 nTPM
GTEx:59.4 nTPM
FANTOM5:11.4 Scaled Tags Per Million
Pig:60.1 nTPM
Mouse:44.8 nTPM
Allen mouse:8.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

148.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 132.6
2586 Male, age 75, left hemisphere 357.0
2828 Female, age 72, unknown 135.6
2219 Male, age 76, both hemispheres 123.3
1830 Male, age 51, unknown 120.0
1833 Male, age 53, unknown 119.0
1827 Male, age 72, unknown 105.2
1870 Female, age 42, unknown 97.1
2666 Male, age 74, left hemisphere 93.0
2019 Male, age 18, unknown 88.1
2411 Female, age 72, unknown 87.4
Dorsal raphe nucleus
nTPM: 125.0
2047 Male, age 72, unknown 164.5
1828 Male, age 53, unknown 150.9
2016 Female, age 72, unknown 119.2
2298 Female, age 72, unknown 100.3
2750 Male, age 76, both hemispheres 90.4
Inferior colliculus
nTPM: 126.1
2849 Male, age 72, unknown 149.2
1848 Female, age 42, unknown 142.3
1890 Male, age 53, unknown 116.8
2097 Female, age 72, unknown 95.9
Median raphe nucleus
nTPM: 98.4
2220 Male, age 76, midline 98.4
Periaquaductal grey, anterior
nTPM: 103.6
2502 Female, age 75, unknown 114.9
1947 Male, age 18, unknown 108.0
1795 Male, age 51, unknown 87.9
Periaquaductal grey, dorsal
nTPM: 112.9
1840 Male, age 53, unknown 122.8
1831 Male, age 72, unknown 111.9
2850 Male, age 76, both hemispheres 111.4
2464 Female, age 72, unknown 105.4
Periaquaductal grey, lateral
nTPM: 99.4
2140 Male, age 76, both hemispheres 119.0
2053 Male, age 18, unknown 106.2
2272 Male, age 74, both hemispheres 73.2
Pretectal area
nTPM: 104.1
1817 Female, age 42, unknown 132.4
2825 Male, age 18, unknown 131.8
2667 Female, age 75, unknown 131.4
2407 Male, age 75, both hemispheres 119.5
1815 Male, age 53, unknown 105.6
1944 Female, age 72, unknown 94.4
2316 Male, age 76, right hemisphere 93.5
2007 Male, age 72, unknown 90.3
2224 Female, age 72, unknown 90.2
1816 Male, age 51, unknown 86.5
2273 Male, age 74, both hemispheres 69.4
Red nucleus
nTPM: 148.5
2588 Male, age 74, left hemisphere 229.1
1954 Female, age 42, unknown 206.1
1821 Female, age 72, unknown 184.1
1865 Male, age 51, unknown 164.9
2227 Male, age 72, unknown 158.7
2769 Male, age 72, unknown 156.3
2503 Female, age 72, unknown 146.3
1904 Male, age 53, unknown 145.9
2823 Male, age 76, right hemisphere 120.8
2584 Male, age 75, left hemisphere 110.0
2785 Male, age 18, unknown 88.4
2725 Female, age 75, unknown 72.0
Substantia nigra
nTPM: 110.7
2699 Male, age 18, unknown 179.7
1916 Female, age 42, unknown 145.9
2583 Male, age 75, right hemisphere 121.6
1851 Male, age 51, unknown 118.5
2665 Male, age 74, both hemispheres 116.7
1889 Female, age 72, unknown 114.7
2241 Male, age 72, unknown 86.0
1941 Male, age 53, unknown 84.0
2590 Female, age 75, unknown 73.6
2409 Female, age 72, unknown 66.8
Superior colliculus
nTPM: 114.1
2668 Female, age 75, unknown 208.9
2664 Male, age 75, both hemispheres 186.8
1796 Male, age 53, unknown 118.0
1839 Male, age 51, unknown 113.4
1895 Male, age 76, right hemisphere 112.1
2087 Female, age 72, unknown 92.7
2261 Male, age 18, unknown 92.7
1995 Male, age 72, unknown 84.8
2587 Male, age 74, left hemisphere 70.3
1913 Female, age 42, unknown 61.5
Ventral tegmental area
nTPM: 96.2
2410 Female, age 72, unknown 111.5
2218 Male, age 76, both hemispheres 101.8
1915 Female, age 42, unknown 97.4
1942 Male, age 51, unknown 95.4
2223 Female, age 72, unknown 89.9
2021 Male, age 53, unknown 81.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

59.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 59.4
Samples: 139

Max nTPM: 267.2
Min nTPM: 9.2
Std nTPM: 41.2
Median nTPM: 49.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 267.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 244.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 205.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 205.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 156.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 144.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 121.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 115.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 113.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 112.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 111.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 111.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 106.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 103.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 100.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 100.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 98.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 97.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 90.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 89.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 86.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 86.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 86.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 85.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 83.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 82.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 81.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 81.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 79.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 78.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 77.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 76.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 76.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 75.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 74.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 72.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 72.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 69.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 68.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 68.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 67.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 66.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 66.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 66.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 65.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 64.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 64.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 64.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 63.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 63.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 61.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 60.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 60.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 59.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 59.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 58.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 57.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 57.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 56.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 56.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 56.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 55.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 55.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 55.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 54.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 53.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 52.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 51.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 49.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 49.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 49.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 48.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 48.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 48.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 47.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 45.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 45.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 45.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 45.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 44.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 44.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 43.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 43.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 43.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 43.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 43.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 43.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 43.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 42.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 42.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 42.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 40.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 40.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 39.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 39.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 38.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 38.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 38.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 38.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 37.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 36.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 36.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 36.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 36.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 35.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 35.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 32.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 32.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 31.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 31.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 31.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 30.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 30.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 29.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 28.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 26.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 25.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 24.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 23.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 22.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 22.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 22.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 21.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 18.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 18.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 18.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 17.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 17.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 16.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 16.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 16.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 15.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 15.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 13.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 13.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 12.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 12.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 12.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 9.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

11.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 11.4
FF:10158-103A5 76 years, female 11.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

60.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 60.1
Samples: 4

Max nTPM: 86.5
Min nTPM: 44.5
Sample A Female 49.1
Sample B Female 44.5
Sample C Male 60.4
Sample D Male 86.5
Midbrain
nTPM: 56.5
Samples: 4

Max nTPM: 75.7
Min nTPM: 47.5
Sample A Female 54.6
Sample B Female 47.5
Sample C Male 75.7
Sample D Male 48.3
Periaqueductal gray
nTPM: 47.9
Samples: 3

Max nTPM: 50.0
Min nTPM: 45.1
Sample B Female 45.1
Sample C Male 50.0
Sample D Male 48.7
Superior colliculi
nTPM: 55.4
Samples: 4

Max nTPM: 64.2
Min nTPM: 40.2
Sample A Female 57.9
Sample B Female 40.2
Sample C Male 59.2
Sample D Male 64.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 44.8
Samples: 4

Max nTPM: 49.8
Min nTPM: 40.9
Sample A Male 49.8
Sample B Male 42.3
Sample C Female 40.9
Sample D Female 46.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.6
75651138 Antisense, RP_060518_01_A01, Mouse strain C57BL/6J (56 days, male) 9.4
71656697 Antisense, RP_050927_04_B05, Mouse strain C57BL/6J (56 days, male) 7.9

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