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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:66.3 nTPM
HPA Brain:93.2 nTPM
GTEx:66.3 nTPM
FANTOM5:93.6 Scaled Tags Per Million
Pig:52.4 nTPM
Mouse:22.3 nTPM
Allen mouse:1.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 64.5
2219 Male, age 76, both hemispheres 81.8
2666 Male, age 74, left hemisphere 70.9
1870 Female, age 42, unknown 69.7
2411 Female, age 72, unknown 68.1
1827 Male, age 72, unknown 62.5
2586 Male, age 75, left hemisphere 62.3
1830 Male, age 51, unknown 62.2
2828 Female, age 72, unknown 62.2
1833 Male, age 53, unknown 60.3
2019 Male, age 18, unknown 45.4
Dorsal raphe nucleus
nTPM: 72.3
2047 Male, age 72, unknown 87.0
1828 Male, age 53, unknown 75.3
2750 Male, age 76, both hemispheres 71.8
2298 Female, age 72, unknown 66.8
2016 Female, age 72, unknown 60.4
Inferior colliculus
nTPM: 57.4
2849 Male, age 72, unknown 61.8
1848 Female, age 42, unknown 58.1
1890 Male, age 53, unknown 55.0
2097 Female, age 72, unknown 54.8
Median raphe nucleus
nTPM: 83.9
2220 Male, age 76, midline 83.9
Periaquaductal grey, anterior
nTPM: 65.1
1947 Male, age 18, unknown 72.2
1795 Male, age 51, unknown 61.7
2502 Female, age 75, unknown 61.2
Periaquaductal grey, dorsal
nTPM: 56.7
1840 Male, age 53, unknown 63.7
2850 Male, age 76, both hemispheres 56.4
2464 Female, age 72, unknown 53.9
1831 Male, age 72, unknown 52.8
Periaquaductal grey, lateral
nTPM: 50.5
2053 Male, age 18, unknown 56.8
2140 Male, age 76, both hemispheres 49.3
2272 Male, age 74, both hemispheres 45.4
Pretectal area
nTPM: 53.4
2825 Male, age 18, unknown 68.6
2407 Male, age 75, both hemispheres 62.0
2224 Female, age 72, unknown 60.7
2667 Female, age 75, unknown 55.2
2316 Male, age 76, right hemisphere 51.3
1944 Female, age 72, unknown 49.7
2273 Male, age 74, both hemispheres 49.0
2007 Male, age 72, unknown 48.5
1815 Male, age 53, unknown 48.2
1816 Male, age 51, unknown 47.4
1817 Female, age 42, unknown 46.6
Red nucleus
nTPM: 63.2
1821 Female, age 72, unknown 76.8
2725 Female, age 75, unknown 73.3
2588 Male, age 74, left hemisphere 71.9
2584 Male, age 75, left hemisphere 68.4
1954 Female, age 42, unknown 62.8
1865 Male, age 51, unknown 62.1
1904 Male, age 53, unknown 60.7
2503 Female, age 72, unknown 60.5
2227 Male, age 72, unknown 59.7
2769 Male, age 72, unknown 58.6
2823 Male, age 76, right hemisphere 55.8
2785 Male, age 18, unknown 47.4
Substantia nigra
nTPM: 93.2
1916 Female, age 42, unknown 145.4
2241 Male, age 72, unknown 119.1
2699 Male, age 18, unknown 115.7
1851 Male, age 51, unknown 110.1
1941 Male, age 53, unknown 103.3
2409 Female, age 72, unknown 78.2
1889 Female, age 72, unknown 67.1
2665 Male, age 74, both hemispheres 66.5
2583 Male, age 75, right hemisphere 64.7
2590 Female, age 75, unknown 62.0
Superior colliculus
nTPM: 55.8
2668 Female, age 75, unknown 69.2
1796 Male, age 53, unknown 63.1
2664 Male, age 75, both hemispheres 62.6
2587 Male, age 74, left hemisphere 59.7
1895 Male, age 76, right hemisphere 57.1
1839 Male, age 51, unknown 57.0
1913 Female, age 42, unknown 50.4
2261 Male, age 18, unknown 48.5
2087 Female, age 72, unknown 47.9
1995 Male, age 72, unknown 42.3
Ventral tegmental area
nTPM: 86.6
1915 Female, age 42, unknown 102.0
2218 Male, age 76, both hemispheres 96.4
2223 Female, age 72, unknown 89.3
1942 Male, age 51, unknown 82.0
2410 Female, age 72, unknown 80.9
2021 Male, age 53, unknown 69.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

66.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 66.3
Samples: 139

Max nTPM: 144.6
Min nTPM: 30.2
Std nTPM: 19.2
Median nTPM: 64.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 144.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 131.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 121.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 120.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 109.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 107.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 103.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 96.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 95.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 94.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 91.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 91.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 90.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 90.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 90.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 89.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 86.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 85.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 85.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 84.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 82.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 82.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 80.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 80.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 80.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 79.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 79.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 79.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 79.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 78.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 78.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 77.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 76.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 76.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 76.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 75.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 75.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 75.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 75.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 75.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 75.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 74.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 73.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 72.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 72.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 71.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 71.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 70.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 70.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 70.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 70.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 69.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 69.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 69.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 69.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 69.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 67.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 67.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 66.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 66.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 66.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 66.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 66.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 65.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 65.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 65.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 64.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 64.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 64.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 64.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 63.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 63.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 63.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 62.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 62.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 62.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 61.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 61.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 61.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 60.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 60.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 60.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 60.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 60.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 59.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 59.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 59.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 58.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 58.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 58.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 57.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 57.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 57.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 57.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 56.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 56.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 55.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 55.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 55.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 55.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 55.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 54.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 54.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 54.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 53.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 53.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 53.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 52.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 52.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 52.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 51.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 51.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 51.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 50.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 50.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 50.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 49.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 48.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 48.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 46.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 46.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 45.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 45.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 44.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 43.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 43.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 43.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 42.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 42.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 41.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 40.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 37.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 37.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 37.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 35.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 33.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 31.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 30.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

93.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 93.6
FF:10158-103A5 76 years, female 93.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

52.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 52.4
Samples: 4

Max nTPM: 66.8
Min nTPM: 39.4
Sample A Female 66.8
Sample B Female 42.0
Sample C Male 61.3
Sample D Male 39.4
Midbrain
nTPM: 42.8
Samples: 4

Max nTPM: 48.2
Min nTPM: 35.2
Sample A Female 48.2
Sample B Female 43.4
Sample C Male 35.2
Sample D Male 44.2
Periaqueductal gray
nTPM: 33.8
Samples: 3

Max nTPM: 39.4
Min nTPM: 29.6
Sample B Female 32.4
Sample C Male 39.4
Sample D Male 29.6
Superior colliculi
nTPM: 40.3
Samples: 4

Max nTPM: 50.7
Min nTPM: 28.3
Sample A Female 50.7
Sample B Female 28.3
Sample C Male 39.1
Sample D Male 42.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

22.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 22.3
Samples: 4

Max nTPM: 24.0
Min nTPM: 20.8
Sample A Male 23.0
Sample B Male 24.0
Sample C Female 21.5
Sample D Female 20.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.5
2453 Antisense, RP_Baylor_103278, Mouse strain C57BL/6J (56 days, male) 1.5
2452 Antisense, RP_Baylor_103278, Mouse strain C57BL/6J (56 days, male) 0.4

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