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CANCER GLIOMA Show tissue menu
BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA
MELANOMA OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RENAL CANCER SKIN CANCER STOMACH CANCER TESTIS CANCER THYROID CANCER UROTHELIAL CANCER
GBM TCGA GBM VALIDATION PROTEIN GBM CPTAC PROTEIN EXPRESSION
ANTIBODIES
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Dictionary
Glioma
Human cancer
Glioblastoma multiforme
GLIOBLASTOMA MULTIFORME (TCGA) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

PLP1 is not prognostic in Glioblastoma Multiforme (TCGA)


Stage:
Survival analysis
Current cut offi

Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

:
Best expression cut offi

Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

: 626.88
Median expressioni

Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

: N/A
Median follow up timei

Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

: N/A
P scorei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

N/A
3-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
3-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
TCGA RNA samplesi

RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average pTPM 510.0
Number of samples 141
Samples
Sample Description pTPM
TCGA-15-1444-01A 21 years, male, white, stage:'--, dead, 1537 days 3821.2
TCGA-06-5411-01A 51 years, male, white, stage:'--, dead, 254 days 2534.6
TCGA-19-2620-01A 70 years, male, white, stage:'--, dead, 148 days 2447.3
TCGA-41-2571-01A 89 years, male, white, stage:'--, dead, 26 days 2051.9
TCGA-06-5410-01A 72 years, female, white, stage:'--, dead, 108 days 2044.3
TCGA-06-0132-01A 49 years, male, white, stage:'--, dead, 771 days 1985.5
TCGA-06-0219-01A 67 years, male, white, stage:'--, dead, 22 days 1840.3
TCGA-19-1390-01A 63 years, female, white, stage:'--, dead, 772 days 1827.6
TCGA-32-1980-01A 72 years, male, white, stage:'--, dead, 36 days 1792.7
TCGA-06-5858-01A 45 years, female, white, stage:'--, alive, 187 days 1639.9
TCGA-76-4927-01A 58 years, male, white, stage:'--, dead, 535 days 1633.0
TCGA-14-1825-01A 70 years, male, white, stage:'--, dead, 232 days 1538.7
TCGA-06-0238-01A 46 years, male, white, stage:'--, dead, 405 days 1516.2
TCGA-28-5215-01A 62 years, female, white, stage:'--, dead, 335 days 1397.8
TCGA-06-0686-01A 53 years, male, white, stage:'--, dead, 432 days 1362.4
TCGA-06-2558-01A 75 years, female, white, stage:'--, dead, 380 days 1290.2
TCGA-06-2570-01A 21 years, female, white, stage:'--, alive, 958 days 1250.2
TCGA-06-2557-01A 76 years, male, black or african american, stage:'--, dead, 33 days 1224.5
TCGA-06-0882-01A 30 years, male, white, stage:'--, dead, 632 days 1034.8
TCGA-16-0846-01A 85 years, male, white, stage:'--, dead, 119 days 994.9
TCGA-14-1829-01A 57 years, male, black or african american, stage:'--, alive, 218 days 979.1
TCGA-06-0749-01A 50 years, male, black or african american, stage:'--, dead, 82 days 966.5
TCGA-06-0184-01A 63 years, male, white, stage:'--, dead, 2126 days 965.1
TCGA-06-0178-01A 38 years, male, white, stage:'--, dead, 2681 days 944.0
TCGA-06-0158-01A 73 years, male, white, stage:'--, dead, 329 days 914.0
TCGA-32-2634-01A 82 years, male, white, stage:'--, alive, 693 days 913.8
TCGA-06-2567-01A 65 years, male, white, stage:'--, dead, 133 days 901.2
TCGA-32-5222-01A 66 years, male, white, stage:'--, dead, 585 days 877.5
TCGA-28-5216-01A 52 years, male, white, stage:'--, alive, 415 days 830.7
TCGA-19-2629-01A 60 years, male, white, stage:'--, dead, 737 days 828.3
TCGA-06-0129-01A 30 years, male, asian, stage:'--, dead, 1024 days 748.3
TCGA-41-5651-01A 59 years, female, black or african american, stage:'--, dead, 460 days 725.4
TCGA-19-5960-01A 56 years, male, white, stage:'--, dead, 455 days 722.3
TCGA-26-5134-01A 74 years, male, white, stage:'--, alive, 167 days 701.5
TCGA-27-2521-01A 34 years, male, white, stage:'--, dead, 510 days 698.1
TCGA-06-2564-01A 50 years, male, white, stage:'--, alive, 181 days 685.0
TCGA-06-5417-01A 45 years, female, white, stage:'--, alive, 155 days 654.5
TCGA-28-5220-01A 67 years, male, white, stage:'--, dead, 388 days 599.3
TCGA-02-0047-01A 78 years, male, white, stage:'--, dead, 448 days 569.6
TCGA-14-0817-01A 69 years, female, white, stage:'--, dead, 164 days 568.5
TCGA-06-0139-01A 40 years, male, white, stage:'--, dead, 362 days 556.8
TCGA-06-0138-01A 43 years, male, white, stage:'--, dead, 737 days 552.4
TCGA-76-4929-01A 76 years, female, white, stage:'--, dead, 111 days 546.5
TCGA-06-0174-01A 54 years, male, white, stage:'--, dead, 98 days 545.9
TCGA-27-1830-01A 57 years, male, white, stage:'--, dead, 154 days 534.6
TCGA-06-1804-01A 81 years, female, white, stage:'--, dead, 414 days 515.3
TCGA-26-5135-01A 72 years, female, white, stage:'--, dead, 270 days 506.3
TCGA-12-0821-01A 62 years, male, white, stage:'--, dead, 323 days 499.2
TCGA-02-2486-01A 64 years, male, white, stage:'--, dead, 618 days 498.4
TCGA-26-1442-01A 43 years, male, white, stage:'--, alive, 953 days 498.1
TCGA-41-3915-01A 48 years, male, white, stage:'--, dead, 360 days 488.2
TCGA-32-2615-01A 62 years, male, white, stage:'--, dead, 485 days 469.1
TCGA-12-0618-01A 49 years, male, white, stage:'--, dead, 395 days 443.6
TCGA-06-0141-01A 62 years, male, white, stage:'--, dead, 313 days 435.8
TCGA-12-3650-01A 46 years, male, white, stage:'--, dead, 333 days 432.0
TCGA-06-2561-01A 53 years, female, white, stage:'--, dead, 537 days 429.3
TCGA-06-0645-01A 55 years, female, white, stage:'--, dead, 175 days 389.1
TCGA-28-2514-01A 45 years, male, asian, stage:'--, alive, 160 days 353.8
TCGA-28-5207-01A 71 years, male, white, stage:'--, dead, 343 days 350.5
TCGA-27-1837-01A 36 years, male, white, stage:'--, dead, 427 days 335.4
TCGA-06-2559-01A 83 years, male, white, stage:'--, dead, 150 days 319.6
TCGA-41-4097-01A 63 years, female, white, stage:'--, dead, 6 days 315.0
TCGA-28-1753-01A 53 years, male, white, stage:'--, alive, 37 days 310.2
TCGA-32-2616-01A 48 years, female, white, stage:'--, dead, 224 days 302.1
TCGA-06-0168-01A 59 years, female, white, stage:'--, dead, 598 days 299.1
TCGA-06-0210-01A 72 years, female, white, stage:'--, dead, 225 days 291.4
TCGA-06-5856-01A 58 years, male, white, stage:'--, dead, 114 days 281.7
TCGA-27-1834-01A 56 years, male, white, stage:'--, dead, 1233 days 281.3
TCGA-06-5416-01A 23 years, female, white, stage:'--, alive, 204 days 275.2
TCGA-12-3653-01A 34 years, female, white, stage:'--, dead, 442 days 257.4
TCGA-14-2554-01A 52 years, female, white, stage:'--, dead, 532 days 238.8
TCGA-26-5139-01A 65 years, female, white, stage:'--, alive, 48 days 237.8
TCGA-27-2523-01A 63 years, male, white, stage:'--, dead, 489 days 237.1
TCGA-32-1982-01A 76 years, female, white, stage:'--, dead, 142 days 234.4
TCGA-06-5413-01A 67 years, male, white, stage:'--, alive, 268 days 233.5
TCGA-06-0646-01A 60 years, male, white, stage:'--, dead, 175 days 225.3
TCGA-12-0616-01A 36 years, female, white, stage:'--, dead, 448 days 220.9
TCGA-41-2572-01A 67 years, male, white, stage:'--, dead, 406 days 220.2
TCGA-06-0157-01A 63 years, female, white, stage:'--, dead, 97 days 219.6
TCGA-08-0386-01A 74 years, male, white, stage:'--, dead, 548 days 215.5
TCGA-06-0644-01A 71 years, male, black or african american, stage:'--, dead, 384 days 204.5
TCGA-26-5132-01A 74 years, male, white, stage:'--, alive, 286 days 202.2
TCGA-19-4065-01A 36 years, male, white, stage:'--, alive, 214 days 201.2
TCGA-06-2563-01A 72 years, female, white, stage:'--, alive, 932 days 196.9
TCGA-28-5208-01A 52 years, male, white, stage:'--, dead, 544 days 194.8
TCGA-06-0744-01A 66 years, male, white, stage:'--, dead, 1426 days 190.5
TCGA-06-0156-01A 57 years, male, white, stage:'--, dead, 178 days 186.0
TCGA-06-5414-01A 61 years, male, white, stage:'--, alive, 273 days 180.3
TCGA-06-0878-01A 74 years, male, white, stage:'--, alive, 218 days 176.1
TCGA-76-4931-01A 70 years, female, white, stage:'--, dead, 279 days 175.4
TCGA-27-1831-01A 66 years, male, white, stage:'--, dead, 505 days 169.5
TCGA-32-1970-01A 59 years, male, white, stage:'--, dead, 468 days 166.1
TCGA-06-2565-01A 59 years, male, asian, stage:'--, dead, 506 days 158.7
TCGA-14-0871-01A 74 years, female, white, stage:'--, dead, 880 days 156.5
TCGA-06-0190-01A 62 years, male, white, stage:'--, dead, 317 days 153.9
TCGA-06-2562-01A 81 years, male, white, stage:'--, dead, 382 days 145.5
TCGA-76-4925-01A 76 years, male, white, stage:'--, dead, 146 days 135.8
TCGA-27-2526-01A 79 years, female, white, stage:'--, dead, 87 days 132.8
TCGA-06-0750-01A 43 years, male, white, stage:'--, dead, 28 days 125.5
TCGA-06-5418-01A 75 years, female, white, stage:'--, dead, 83 days 122.9
TCGA-06-5412-01A 78 years, female, white, stage:'--, dead, 138 days 122.4
TCGA-32-2632-01A 80 years, male, white, stage:'--, dead, 269 days 121.2
TCGA-06-0130-01A 54 years, male, white, stage:'--, dead, 394 days 120.5
TCGA-12-5299-01A 56 years, female, white, stage:'--, dead, 98 days 114.1
TCGA-32-2638-01A 67 years, male, white, stage:'--, dead, 766 days 109.9
TCGA-02-2485-01A 53 years, male, black or african american, stage:'--, alive, 470 days 106.6
TCGA-06-5859-01A 63 years, male, white, stage:'--, alive, 139 days 105.2
TCGA-32-4213-01A 47 years, female, white, stage:'--, alive, 604 days 103.1
TCGA-27-2519-01A 48 years, male, white, stage:'--, dead, 550 days 98.8
TCGA-27-2524-01A 56 years, male, white, stage:'--, dead, 231 days 97.0
TCGA-06-0125-01A 63 years, female, white, stage:'--, dead, 1448 days 94.7
TCGA-19-2624-01A 51 years, male, white, stage:'--, dead, 5 days 91.1
TCGA-76-4932-01A 50 years, female, white, stage:'--, dead, 1458 days 86.8
TCGA-06-0745-01A 59 years, male, white, stage:'--, dead, 239 days 86.6
TCGA-12-3652-01A 60 years, male, white, stage:'--, dead, 1062 days 84.2
TCGA-28-5209-01A 66 years, female, white, stage:'--, alive, 442 days 81.4
TCGA-12-5295-01A 60 years, female, white, stage:'--, dead, 454 days 80.1
TCGA-06-2569-01A 24 years, female, black or african american, stage:'--, alive, 13 days 78.1
TCGA-26-5133-01A 59 years, male, white, stage:'--, alive, 452 days 75.2
TCGA-14-0787-01A 69 years, male, asian, stage:'--, dead, 68 days 74.3
TCGA-27-2528-01A 62 years, male, white, stage:'--, dead, 480 days 71.6
TCGA-02-2483-01A 43 years, male, asian, stage:'--, alive, 466 days 67.8
TCGA-06-0743-01A 69 years, male, white, stage:'--, dead, 803 days 65.8
TCGA-28-5204-01A 72 years, male, white, stage:'--, dead, 454 days 64.0
TCGA-12-0619-01A 60 years, male, white, stage:'--, dead, 1062 days 62.5
TCGA-28-2513-01A 69 years, female, white, stage:'--, alive, 222 days 58.3
TCGA-14-1823-01A 58 years, female, white, stage:'--, dead, 543 days 57.4
TCGA-19-2619-01A 55 years, female, black or african american, stage:'--, alive, 294 days 56.8
TCGA-06-0187-01A 69 years, male, white, stage:'--, dead, 828 days 55.4
TCGA-28-5218-01A 63 years, male, white, stage:'--, dead, 157 days 54.5
TCGA-06-0747-01A 53 years, male, white, stage:'--, dead, 82 days 51.0
TCGA-02-0055-01A 62 years, female, white, stage:'--, dead, 76 days 49.9
TCGA-14-0789-01A 54 years, male, white, stage:'--, dead, 342 days 41.7
TCGA-06-5408-01A 54 years, female, white, stage:'--, dead, 357 days 40.7
TCGA-19-2625-01A 76 years, female, white, stage:'--, dead, 124 days 36.3
TCGA-28-2509-01A 77 years, female, white, stage:'--, alive, 145 days 35.1
TCGA-15-0742-01A 65 years, male, white, stage:'--, dead, 419 days 31.3
TCGA-27-1835-01A 53 years, female, white, stage:'--, dead, 648 days 28.7
TCGA-06-0211-01A 47 years, male, white, stage:'--, dead, 360 days 24.1
TCGA-27-1832-01A 59 years, female, white, stage:'--, dead, 300 days 23.1
TCGA-14-1034-01A 60 years, female, stage:'--, dead, 485 days 19.7
Show allShow less
GLIOBLASTOMA MULTIFORME (VALIDATION) - Interactive survival scatter ploti

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisi

Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

PLP1 is not prognostic in Glioblastoma Multiforme (validation)


Stage:
Survival analysis
Current cut offi

Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

:
Best expression cut offi

Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

: 153.12
Median expressioni

Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

: N/A
Median follow up timei

Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

: N/A
P scorei

Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

N/A
3-year survival highi

5-year survival for patients with higher expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
3-year survival lowi

5-year survival for patients with lower expression than the expression cutoff.

For melanoma and glioma, 3-year survival is shown.

N/A
TCGA RNA samplesi

RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

Average pTPM 721.7
Number of samples 58
Samples
Sample Description pTPM
AK134 N, NA, stage:NA, dead, 360 days 6197.4
AK015 N, NA, stage:NA, alive, 720 days 3653.1
AK149 N, NA, stage:NA, dead, 420 days 2761.0
AK079 N, NA, stage:NA, dead, 210 days 2582.7
AK173 N, NA, stage:NA, dead, 180 days 2222.9
AK167 N, NA, stage:NA, dead, 180 days 1970.6
AK006 N, NA, stage:NA, dead, 360 days 1452.1
AK076 N, NA, stage:NA, alive, 660 days 1347.6
AK003 N, NA, stage:NA, dead, 600 days 1303.0
AK188 N, NA, stage:NA, alive, 420 days 1244.6
AK156 N, NA, stage:NA, dead, 330 days 1217.0
AK158 N, NA, stage:NA, dead, 360 days 1047.9
AK231 N, NA, stage:NA, dead, 240 days 883.0
AK165 N, NA, stage:NA, alive, 360 days 786.7
AK072 N, NA, stage:NA, dead, 150 days 692.6
AK051 N, NA, stage:NA, dead, 360 days 643.4
AK102 N, NA, stage:NA, alive, 1740 days 615.2
AK043 N, NA, stage:NA, alive, 660 days 602.1
AK041 N, NA, stage:NA, alive, 810 days 597.7
AK081 N, NA, stage:NA, dead, 180 days 576.2
AK226 N, NA, stage:NA, dead, 360 days 545.2
AK103 N, NA, stage:NA, alive, 1320 days 536.2
AK049 N, NA, stage:NA, dead, 180 days 512.0
AK030 N, NA, stage:NA, dead, 120 days 468.1
AK142 N, NA, stage:NA, alive, 90 days 418.8
AK133 N, NA, stage:NA, dead, 360 days 384.9
AK199 N, NA, stage:NA, alive, 1860 days 373.4
AK124 N, NA, stage:NA, alive, 1920 days 360.7
AK002 N, NA, stage:NA, dead, 570 days 356.2
AK071 N, NA, stage:NA, dead, 540 days 350.9
AK085 N, NA, stage:NA, alive, 660 days 345.0
AK227 N, NA, stage:NA, alive, 300 days 342.7
AK183 N, NA, stage:NA, alive, 360 days 307.2
AK089 N, NA, stage:NA, dead, 330 days 304.6
AK074 N, NA, stage:NA, alive, 300 days 297.5
AK216 N, NA, stage:NA, dead, 360 days 296.7
AK091 N, NA, stage:NA, dead, 210 days 274.6
AK055 N, NA, stage:NA, dead, 240 days 267.1
AK213 N, NA, stage:NA, alive, 2010 days 260.9
AK088 N, NA, stage:NA, dead, 360 days 256.4
AK185 N, NA, stage:NA, alive, 330 days 243.4
AK100 N, NA, stage:NA, alive, 960 days 228.1
AK098 N, NA, stage:NA, dead, 660 days 198.4
AK117 N, NA, stage:NA, dead, 210 days 195.4
AK066 N, NA, stage:NA, alive, 960 days 175.4
AK099 N, NA, stage:NA, dead, 420 days 158.6
AK139 N, NA, stage:NA, dead, 270 days 147.7
AK123 N, NA, stage:NA, dead, 180 days 125.5
AK195 N, NA, stage:NA, dead, 390 days 118.7
AK035 N, NA, stage:NA, dead, 210 days 102.6
AK053 N, NA, stage:NA, dead, 300 days 92.2
AK068 N, NA, stage:NA, alive, 360 days 85.8
AK178 N, NA, stage:NA, dead, 240 days 84.2
AK218 N, NA, stage:NA, dead, 180 days 68.2
AK005 N, NA, stage:NA, dead, 240 days 60.0
AK153 N, NA, stage:NA, dead, 240 days 57.9
AK236 N, NA, stage:NA, dead, 360 days 50.5
AK205 N, NA, stage:NA, dead, 120 days 11.7
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GLIOBLASTOMA MULTIFORME - Protein relative expression (CPTAC)
Number of samples 110
Samples
Sample ID Sample type nRPX
CPT0196850003 Tumor 2.5
CPT0204350003 Normal 2.3
CPT0204330003 Normal 2.3
CPT0206450003 Tumor 2.2
CPT0204420003 Normal 2.2
CPT0204390003 Normal 2.0
CPT0104220003 Tumor 1.9
CPT0204360003 Normal 1.8
CPT0204380003 Normal 1.8
CPT0209440003 Tumor 1.7
CPT0204410003 Normal 1.6
CPT0204370003 Normal 1.5
CPT0168720003 Tumor 1.5
CPT0204400003 Normal 1.5
CPT0190360004 Tumor 1.4
CPT0204340003 Normal 1.3
CPT0190240004 Tumor 1.3
CPT0189250003 Tumor 0.9
CPT0104330003 Tumor 0.7
CPT0167970003 Tumor 0.6
CPT0206330003 Tumor 0.5
CPT0162020003 Tumor 0.3
CPT0207030003 Tumor 0.2
CPT0168480003 Tumor 0.1
CPT0199770003 Tumor 0.1
CPT0189460003 Tumor 0.0
CPT0206880003 Tumor -0.1
CPT0162140003 Tumor -0.1
CPT0205450004 Tumor -0.2
CPT0221180003 Tumor -0.3
CPT0225760003 Tumor -0.3
CPT0189650004 Tumor -0.3
CPT0205670004 Tumor -0.4
CPT0224330003 Tumor -0.4
CPT0207090003 Tumor -0.4
CPT0168270003 Tumor -0.5
CPT0218960004 Tumor -0.5
CPT0182580003 Tumor -0.5
CPT0205890003 Tumor -0.5
CPT0167750004 Tumor -0.6
CPT0217880003 Tumor -0.6
CPT0219080004 Tumor -0.6
CPT0092440003 Tumor -0.6
CPT0168590003 Tumor -0.6
CPT0064650003 Tumor -0.7
CPT0167860004 Tumor -0.7
CPT0093550003 Tumor -0.7
CPT0168380003 Tumor -0.8
CPT0217000004 Tumor -0.8
CPT0218330004 Tumor -0.8
CPT0087950003 Tumor -0.8
CPT0201710003 Tumor -0.8
CPT0218690004 Tumor -0.9
CPT0189850004 Tumor -0.9
CPT0182550003 Tumor -1.0
CPT0228220003 Tumor -1.1
CPT0224600003 Tumor -1.1
CPT0205780003 Tumor -1.1
CPT0087730003 Tumor -1.2
CPT0167640003 Tumor -1.2
CPT0206000004 Tumor -1.3
CPT0089150003 Tumor -1.3
CPT0218770003 Tumor -1.3
CPT0218890004 Tumor -1.3
CPT0189570004 Tumor -1.4
CPT0087570003 Tumor -1.4
CPT0125220003 Tumor -1.4
CPT0189750004 Tumor -1.4
CPT0125570003 Tumor -1.4
CPT0167530003 Tumor -1.4
CPT0162100003 Tumor -1.4
CPT0002410011 Tumor -1.5
CPT0186100003 Tumor -1.5
CPT0217190003 Tumor -1.5
CPT0205570003 Tumor -1.5
CPT0125510003 Tumor -1.5
CPT0161730003 Tumor -1.5
CPT0206560003 Tumor -1.6
CPT0218670003 Tumor -1.6
CPT0206110003 Tumor -1.6
CPT0224540004 Tumor -1.7
CPT0217100003 Tumor -1.7
CPT0093590003 Tumor -1.7
CPT0206670004 Tumor -1.7
CPT0217430008 Tumor -1.7
CPT0224390004 Tumor -1.7
CPT0225730003 Tumor -1.7
CPT0175060003 Tumor -1.8
CPT0093360003 Tumor -1.8
CPT0093450003 Tumor -1.8
CPT0216920008 Tumor -1.8
CPT0127420003 Tumor -1.8
CPT0182500003 Tumor -1.8
CPT0087680003 Tumor -1.8
CPT0168080003 Tumor -1.8
CPT0208980003 Tumor -1.8
CPT0078580003 Tumor -1.9
CPT0217060003 Tumor -1.9
CPT0093510003 Tumor -2.0
CPT0218830004 Tumor -2.0
CPT0071100003 Tumor -2.0
CPT0206780003 Tumor -2.0
CPT0171580008 Tumor -2.0
CPT0079790003 Tumor -2.1
CPT0206230003 Tumor -2.2
CPT0064890003 Tumor -2.4
CPT0123530003 Tumor -2.5
CPT0127480003 Tumor -2.5
CPT0217710008 Tumor -2.5
CPT0168830003 Tumor -2.6
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GLIOMA - Protein expressioni

A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

 

Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.


Antibody HPA004128
 Staining
  High
  Medium
  Low
  Not detected
 Intensity
  Strong
  Moderate
  Weak
  Negative
 Quantity
  >75%
  75%-25%
  <25%
  None
 Location
  Nuclear
  Cytoplasmic/membranous
  Cytoplasmic/membranous,nuclear
  None
Glioma, malignant, High grade
Glioma, malignant, Low grade
Glioma, malignant, NOS

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