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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:104.0 nTPM
HPA Brain:26.9 nTPM
GTEx:104.0 nTPM
FANTOM5:404.9 Scaled Tags Per Million
Pig:196.1 nTPM
Mouse:521.2 nTPM
Allen mouse:3.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

26.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 20.9
2411 Female, age 72, unknown 27.3
2019 Male, age 18, unknown 25.1
1870 Female, age 42, unknown 23.1
2219 Male, age 76, both hemispheres 20.6
2828 Female, age 72, unknown 20.5
1827 Male, age 72, unknown 19.9
1830 Male, age 51, unknown 18.9
2666 Male, age 74, left hemisphere 18.6
1833 Male, age 53, unknown 18.1
2586 Male, age 75, left hemisphere 16.7
Dorsal raphe nucleus
nTPM: 21.9
2047 Male, age 72, unknown 23.8
2298 Female, age 72, unknown 23.0
1828 Male, age 53, unknown 22.4
2750 Male, age 76, both hemispheres 20.7
2016 Female, age 72, unknown 19.8
Inferior colliculus
nTPM: 22.2
1890 Male, age 53, unknown 24.4
2097 Female, age 72, unknown 23.8
1848 Female, age 42, unknown 22.9
2849 Male, age 72, unknown 17.6
Median raphe nucleus
nTPM: 19.7
2220 Male, age 76, midline 19.7
Periaquaductal grey, anterior
nTPM: 21.8
1947 Male, age 18, unknown 24.4
2502 Female, age 75, unknown 21.4
1795 Male, age 51, unknown 19.6
Periaquaductal grey, dorsal
nTPM: 20.1
1840 Male, age 53, unknown 24.8
2464 Female, age 72, unknown 19.3
2850 Male, age 76, both hemispheres 18.5
1831 Male, age 72, unknown 17.7
Periaquaductal grey, lateral
nTPM: 19.1
2053 Male, age 18, unknown 21.8
2140 Male, age 76, both hemispheres 17.9
2272 Male, age 74, both hemispheres 17.4
Pretectal area
nTPM: 21.5
2007 Male, age 72, unknown 27.8
1817 Female, age 42, unknown 25.8
1816 Male, age 51, unknown 24.2
1944 Female, age 72, unknown 22.7
2316 Male, age 76, right hemisphere 21.4
2667 Female, age 75, unknown 21.0
1815 Male, age 53, unknown 20.0
2273 Male, age 74, both hemispheres 20.0
2224 Female, age 72, unknown 19.4
2825 Male, age 18, unknown 18.0
2407 Male, age 75, both hemispheres 16.7
Red nucleus
nTPM: 24.8
1821 Female, age 72, unknown 29.5
1865 Male, age 51, unknown 28.8
2503 Female, age 72, unknown 28.2
2769 Male, age 72, unknown 26.2
1904 Male, age 53, unknown 25.9
1954 Female, age 42, unknown 25.5
2227 Male, age 72, unknown 24.8
2725 Female, age 75, unknown 23.7
2588 Male, age 74, left hemisphere 23.3
2785 Male, age 18, unknown 22.9
2823 Male, age 76, right hemisphere 22.5
2584 Male, age 75, left hemisphere 16.2
Substantia nigra
nTPM: 26.9
2409 Female, age 72, unknown 37.8
1916 Female, age 42, unknown 34.4
1851 Male, age 51, unknown 33.6
1889 Female, age 72, unknown 27.0
2241 Male, age 72, unknown 25.2
1941 Male, age 53, unknown 24.9
2590 Female, age 75, unknown 24.6
2665 Male, age 74, both hemispheres 22.7
2699 Male, age 18, unknown 21.3
2583 Male, age 75, right hemisphere 17.8
Superior colliculus
nTPM: 20.7
2587 Male, age 74, left hemisphere 26.4
2668 Female, age 75, unknown 23.3
1895 Male, age 76, right hemisphere 22.6
1913 Female, age 42, unknown 21.0
2087 Female, age 72, unknown 20.8
2261 Male, age 18, unknown 20.5
1995 Male, age 72, unknown 20.3
1796 Male, age 53, unknown 20.1
1839 Male, age 51, unknown 17.1
2664 Male, age 75, both hemispheres 14.7
Ventral tegmental area
nTPM: 26.4
2410 Female, age 72, unknown 35.7
1915 Female, age 42, unknown 29.0
2223 Female, age 72, unknown 25.6
2218 Male, age 76, both hemispheres 23.2
2021 Male, age 53, unknown 22.7
1942 Male, age 51, unknown 22.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

104.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 104.0
Samples: 139

Max nTPM: 225.6
Min nTPM: 33.1
Std nTPM: 33.0
Median nTPM: 94.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 225.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 209.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 188.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 184.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 177.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 168.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 167.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 164.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 163.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 156.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 155.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 154.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 153.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 150.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 148.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 147.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 145.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 144.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 141.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 138.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 136.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 135.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 134.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 133.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 131.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 130.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 130.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 127.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 126.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 126.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 125.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 125.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 124.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 122.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 122.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 120.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 120.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 119.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 119.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 117.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 117.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 116.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 116.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 114.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 114.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 114.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 113.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 113.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 112.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 110.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 110.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 109.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 108.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 108.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 107.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 105.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 105.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 105.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 103.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 101.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 101.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 101.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 100.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 100.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 99.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 98.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 97.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 97.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 95.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 94.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 94.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 93.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 93.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 93.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 92.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 92.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 92.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 92.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 91.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 91.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 91.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 91.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 91.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 91.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 90.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 90.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 90.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 90.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 89.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 89.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 89.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 88.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 88.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 87.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 87.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 87.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 87.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 86.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 86.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 86.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 86.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 86.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 84.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 84.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 83.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 83.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 83.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 82.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 80.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 80.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 79.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 79.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 79.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 78.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 78.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 77.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 77.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 75.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 75.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 73.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 73.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 73.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 71.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 70.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 69.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 67.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 66.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 66.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 64.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 61.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 58.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 57.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 56.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 52.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 50.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 46.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 45.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 33.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

404.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 404.9
FF:10158-103A5 76 years, female 404.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

196.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 164.8
Samples: 4

Max nTPM: 241.0
Min nTPM: 129.9
Sample A Female 241.0
Sample B Female 156.6
Sample C Male 131.5
Sample D Male 129.9
Midbrain
nTPM: 180.8
Samples: 4

Max nTPM: 270.3
Min nTPM: 126.3
Sample A Female 270.3
Sample B Female 170.6
Sample C Male 156.0
Sample D Male 126.3
Periaqueductal gray
nTPM: 133.2
Samples: 3

Max nTPM: 145.8
Min nTPM: 113.6
Sample B Female 145.8
Sample C Male 140.1
Sample D Male 113.6
Superior colliculi
nTPM: 196.1
Samples: 4

Max nTPM: 242.2
Min nTPM: 144.7
Sample A Female 242.2
Sample B Female 209.3
Sample C Male 188.3
Sample D Male 144.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

521.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 521.2
Samples: 4

Max nTPM: 609.5
Min nTPM: 431.0
Sample A Male 609.5
Sample B Male 482.0
Sample C Female 431.0
Sample D Female 562.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.4
69173370 Antisense, RP_050329_01_E03, Mouse strain C57BL/6J (56 days, male) 3.4

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