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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
121.1
nTPM
HPA:
107.3
nTPM
GTEx:
121.1
nTPM
FANTOM5:
119.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA021283
Antibody HPA021332
Cholangiocytes
Medium
Medium
Hepatocytes
High
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
107.3
Female, age 60
Liver sample 21 nTPM: 93.2
Male, age 54
Liver sample 23 nTPM: 55.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 99.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 113.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 97.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 84.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 38.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 229.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 124.9
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 136.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
121.1
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 121.1
Samples: 226
Max nTPM: 318.3
Min nTPM: 26.4
Std nTPM: 48.7
Median nTPM: 116.9
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
318.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
280.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
270.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
236.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
235.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
225.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
224.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
223.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
223.2
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
219.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
213.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
212.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
203.5
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
201.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
196.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
193.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
191.3
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
189.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
189.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
189.2
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
188.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
187.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
187.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
186.5
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
186.4
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
185.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
183.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
179.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
175.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
175.7
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
175.0
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
173.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
173.3
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
171.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
169.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
169.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
168.7
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
167.8
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
165.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
165.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
165.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
165.2
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
164.5
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
164.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
162.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
162.6
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
160.4
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
159.2
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
158.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
155.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
154.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
153.9
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
151.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
150.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
149.0
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
148.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
147.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
146.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
145.5
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
145.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
143.8
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
143.0
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
141.8
GTEX-14PHX-0526-SM-664NW
50-59 years, male
141.5
GTEX-YECK-1926-SM-4W21H
60-69 years, male
140.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
140.6
GTEX-13112-1426-SM-5EGH8
50-59 years, male
140.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
139.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
139.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
137.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
137.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
137.4
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
136.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
135.3
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
135.3
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
134.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
133.7
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
133.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
133.3
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
132.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
131.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
131.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
131.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
131.5
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
131.0
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
130.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
130.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
130.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
130.4
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
129.5
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
128.9
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
128.4
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
128.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
127.8
GTEX-P78B-1326-SM-3P611
40-49 years, female
127.5
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
126.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
125.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
124.7
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
124.7
GTEX-13113-1326-SM-5GCOI
60-69 years, female
124.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
124.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
123.8
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
122.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
122.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
122.0
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
120.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
119.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
119.8
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
119.4
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
118.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
118.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
117.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
117.5
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
116.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
114.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
114.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
112.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
112.3
GTEX-14E7W-1526-SM-6871X
70-79 years, male
111.9
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
111.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
111.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
111.3
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
110.8
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
110.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
109.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
109.2
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
108.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
108.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
108.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
108.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
107.9
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
107.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
106.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
106.7
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
106.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
106.0
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
105.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
105.5
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
103.6
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
103.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
103.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
102.6
GTEX-11GSP-0626-SM-5986T
60-69 years, female
102.3
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
101.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
100.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
100.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
99.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
99.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
98.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
97.4
GTEX-RN64-1826-SM-48FDV
50-59 years, male
97.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
95.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
94.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
93.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
93.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
93.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
93.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
93.1
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
91.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
91.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
91.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
91.0
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
90.5
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
89.6
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
89.4
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
87.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
86.0
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
85.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
84.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
84.0
GTEX-QEL4-1226-SM-447A4
50-59 years, male
82.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
82.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
82.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
81.0
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
80.8
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
80.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
79.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
79.1
GTEX-12696-0826-SM-5EGGE
60-69 years, male
78.7
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
78.5
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
77.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
77.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
75.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
75.8
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
75.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
75.4
GTEX-O5YV-0726-SM-EV798
60-69 years, female
74.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
74.0
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
73.4
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
70.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
70.3
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
70.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
70.1
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
69.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
68.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
67.1
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
66.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
66.8
GTEX-17F96-1226-SM-79OK2
70-79 years, male
65.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
64.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
64.6
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
62.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
62.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
61.8
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
61.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
61.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
60.6
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
60.3
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
60.2
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
59.6
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
59.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
57.7
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
55.9
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
54.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
54.5
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
53.9
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
53.6
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
52.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
51.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
46.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
44.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
43.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
38.4
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
37.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
33.3
GTEX-Q734-0326-SM-48U15
40-49 years, female
26.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
