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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:21.4 nTPM
HPA Brain:66.7 nTPM
GTEx:21.4 nTPM
FANTOM5:146.5 Scaled Tags Per Million
Pig:48.1 nTPM
Mouse:43.3 nTPM
Allen mouse:2.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

66.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 56.9
1870 Female, age 42, unknown 65.6
2411 Female, age 72, unknown 62.7
1833 Male, age 53, unknown 62.0
1830 Male, age 51, unknown 60.1
2019 Male, age 18, unknown 58.3
2219 Male, age 76, both hemispheres 56.3
1827 Male, age 72, unknown 55.8
2828 Female, age 72, unknown 55.1
2666 Male, age 74, left hemisphere 49.1
2586 Male, age 75, left hemisphere 43.5
Dorsal raphe nucleus
nTPM: 64.7
2298 Female, age 72, unknown 69.8
2750 Male, age 76, both hemispheres 66.2
2016 Female, age 72, unknown 64.8
2047 Male, age 72, unknown 64.2
1828 Male, age 53, unknown 58.6
Inferior colliculus
nTPM: 55.6
2097 Female, age 72, unknown 60.2
1890 Male, age 53, unknown 55.8
1848 Female, age 42, unknown 55.5
2849 Male, age 72, unknown 51.0
Median raphe nucleus
nTPM: 66.7
2220 Male, age 76, midline 66.7
Periaquaductal grey, anterior
nTPM: 61.2
1947 Male, age 18, unknown 70.3
2502 Female, age 75, unknown 60.2
1795 Male, age 51, unknown 53.0
Periaquaductal grey, dorsal
nTPM: 57.5
2850 Male, age 76, both hemispheres 63.6
1840 Male, age 53, unknown 57.9
1831 Male, age 72, unknown 55.0
2464 Female, age 72, unknown 53.7
Periaquaductal grey, lateral
nTPM: 55.2
2272 Male, age 74, both hemispheres 57.2
2140 Male, age 76, both hemispheres 55.7
2053 Male, age 18, unknown 52.8
Pretectal area
nTPM: 58.0
2273 Male, age 74, both hemispheres 65.7
2667 Female, age 75, unknown 65.5
2224 Female, age 72, unknown 65.0
1815 Male, age 53, unknown 58.8
1817 Female, age 42, unknown 57.3
2316 Male, age 76, right hemisphere 57.3
2007 Male, age 72, unknown 55.4
2825 Male, age 18, unknown 55.4
1944 Female, age 72, unknown 53.8
2407 Male, age 75, both hemispheres 52.6
1816 Male, age 51, unknown 51.6
Red nucleus
nTPM: 57.4
1954 Female, age 42, unknown 66.5
1821 Female, age 72, unknown 65.8
2725 Female, age 75, unknown 63.0
2823 Male, age 76, right hemisphere 62.1
1865 Male, age 51, unknown 61.8
1904 Male, age 53, unknown 61.3
2503 Female, age 72, unknown 57.6
2227 Male, age 72, unknown 54.6
2769 Male, age 72, unknown 53.2
2785 Male, age 18, unknown 51.5
2584 Male, age 75, left hemisphere 47.1
2588 Male, age 74, left hemisphere 44.1
Substantia nigra
nTPM: 64.6
2241 Male, age 72, unknown 82.6
1916 Female, age 42, unknown 75.5
2699 Male, age 18, unknown 68.0
1851 Male, age 51, unknown 67.5
2409 Female, age 72, unknown 67.2
1941 Male, age 53, unknown 63.1
1889 Female, age 72, unknown 61.4
2583 Male, age 75, right hemisphere 54.6
2590 Female, age 75, unknown 53.8
2665 Male, age 74, both hemispheres 52.6
Superior colliculus
nTPM: 54.7
1913 Female, age 42, unknown 61.4
2587 Male, age 74, left hemisphere 60.8
1995 Male, age 72, unknown 56.9
1839 Male, age 51, unknown 56.2
2087 Female, age 72, unknown 55.4
1895 Male, age 76, right hemisphere 55.3
2668 Female, age 75, unknown 52.2
2261 Male, age 18, unknown 51.8
1796 Male, age 53, unknown 51.4
2664 Male, age 75, both hemispheres 45.8
Ventral tegmental area
nTPM: 62.6
1915 Female, age 42, unknown 64.9
2410 Female, age 72, unknown 64.7
1942 Male, age 51, unknown 64.0
2218 Male, age 76, both hemispheres 63.6
2021 Male, age 53, unknown 61.0
2223 Female, age 72, unknown 57.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

21.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 21.4
Samples: 139

Max nTPM: 34.5
Min nTPM: 13.2
Std nTPM: 4.0
Median nTPM: 20.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 34.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 31.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 31.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 30.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 29.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 29.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 28.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 28.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 27.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 27.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 27.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 26.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 26.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 26.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 26.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 26.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 26.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 26.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 25.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 25.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 25.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 25.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 25.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 25.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 25.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 25.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 25.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 25.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 25.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 25.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 24.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 24.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 24.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 24.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 24.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 24.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 24.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 23.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 23.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 23.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 23.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 23.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 23.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 23.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 23.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 22.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 22.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 22.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 22.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 22.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 22.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 22.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 22.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 22.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 22.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 22.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 22.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 21.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 21.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 21.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 21.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 21.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 21.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 21.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 21.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 21.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 21.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 21.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 21.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 20.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 20.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 20.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 20.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 20.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 20.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 20.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 20.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 20.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 20.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 20.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 20.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 20.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 20.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 20.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 20.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 20.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 20.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 20.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 19.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 19.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 19.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 19.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 19.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 19.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 19.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 19.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 19.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 19.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 18.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 18.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 18.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 18.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 18.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 18.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 18.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 18.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 18.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 18.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 17.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 17.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 17.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 17.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 17.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 17.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 17.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 16.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 16.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 16.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 16.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 16.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 16.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 16.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 16.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 16.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 16.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 16.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 16.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 15.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 15.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 15.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 14.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 14.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 14.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 14.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 14.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 14.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 13.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 13.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

146.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 146.5
FF:10158-103A5 76 years, female 146.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

48.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 48.1
Samples: 4

Max nTPM: 51.3
Min nTPM: 43.1
Sample A Female 50.9
Sample B Female 47.0
Sample C Male 51.3
Sample D Male 43.1
Midbrain
nTPM: 47.9
Samples: 4

Max nTPM: 55.3
Min nTPM: 43.1
Sample A Female 55.3
Sample B Female 43.1
Sample C Male 49.4
Sample D Male 43.8
Periaqueductal gray
nTPM: 42.6
Samples: 3

Max nTPM: 47.3
Min nTPM: 39.5
Sample B Female 41.1
Sample C Male 47.3
Sample D Male 39.5
Superior colliculi
nTPM: 46.3
Samples: 4

Max nTPM: 49.6
Min nTPM: 43.7
Sample A Female 49.6
Sample B Female 48.1
Sample C Male 43.7
Sample D Male 43.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

43.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 43.3
Samples: 4

Max nTPM: 46.1
Min nTPM: 41.2
Sample A Male 41.2
Sample B Male 46.1
Sample C Female 44.4
Sample D Female 41.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.0
2631 Antisense, RP_040420_01_G07, Mouse strain C57BL/6J (56 days, male) 4.0
2632 Antisense, RP_040420_01_G07, Mouse strain C57BL/6J (56 days, male) 3.0
71148070 Antisense, RP_050719_03_A12, Mouse strain C57BL/6J (56 days, male) 0.1

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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