Expression of PPDPF in urothelial cancer

BLADDER UROTHELIAL CARCINOMA (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

PPDPF is not prognostic in Bladder Urothelial Carcinoma (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 797.51

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average pTPM

817.4

Number of samples

169

Samples

Sample	Description	pTPM
TCGA-BT-A20P-01A	81 years, female, white, stage:Stage III, dead, 544 days	4209.1
TCGA-DK-A3IL-01A	79 years, female, white, stage:Stage IV, dead, 413 days	3159.8
TCGA-XF-AAMX-01A	87 years, female, black or african american, stage:Stage III, dead, 206 days	2552.1
TCGA-XF-A9SV-01A	82 years, male, white, stage:Stage IV, dead, 388 days	2297.3
TCGA-XF-AAMZ-01A	81 years, female, white, stage:Stage IV, dead, 1348 days	2279.8
TCGA-ZF-A9R9-01A	58 years, male, white, stage:Stage IV, dead, 864 days	2277.9
TCGA-DK-AA6L-01A	48 years, male, white, stage:Stage IV, dead, 1163 days	2217.3
TCGA-DK-AA75-01A	82 years, male, white, stage:Stage III, dead, 340 days	2102.2
TCGA-XF-A9SU-01A	74 years, female, white, stage:Stage IV, dead, 182 days	1997.8
TCGA-G2-A3IE-01A	51 years, male, white, stage:Stage II, dead, 612 days	1972.4
TCGA-XF-A9SX-01A	63 years, female, white, stage:Stage IV, dead, 719 days	1703.7
TCGA-4Z-AA7S-01A	66 years, male, black or african american, stage:Stage III, dead, 1064 days	1631.5
TCGA-DK-A3IN-01A	72 years, male, white, stage:Stage III, dead, 250 days	1604.9
TCGA-BT-A20T-01A	63 years, male, white, stage:Stage IV, dead, 453 days	1562.6
TCGA-4Z-AA81-01A	80 years, male, white, stage:Stage II, dead, 1270 days	1525.5
TCGA-ZF-AA52-01A	70 years, male, white, stage:Stage III, dead, 1077 days	1500.8
TCGA-GU-A767-01A	81 years, male, white, stage:Stage IV, dead, 144 days	1473.0
TCGA-ZF-AA4U-01A	70 years, male, white, stage:Stage III, dead, 262 days	1472.6
TCGA-E7-A541-01A	66 years, male, white, stage:Stage II, dead, 778 days	1457.4
TCGA-GU-A42P-01A	72 years, male, white, stage:Stage IV, dead, 332 days	1436.2
TCGA-4Z-AA80-01A	73 years, male, white, stage:Stage II, dead, 19 days	1419.5
TCGA-UY-A78M-01A	81 years, female, asian, stage:Stage IV, dead, 690 days	1413.5
TCGA-DK-A2HX-01A	80 years, female, white, stage:Stage IV, dead, 1420 days	1397.6
TCGA-FD-A5BZ-01A	77 years, female, white, stage:Stage IV, dead, 835 days	1377.9
TCGA-2F-A9KR-01A	59 years, female, stage:Stage III, dead, 3183 days	1371.7
TCGA-DK-A3X2-01A	85 years, male, white, stage:Stage IV, dead, 547 days	1362.3
TCGA-XF-A8HF-01A	80 years, male, white, stage:Stage III, dead, 2954 days	1326.5
TCGA-UY-A78N-01A	80 years, male, white, stage:Stage IV, dead, 2641 days	1320.1
TCGA-XF-A9SJ-01A	83 years, male, white, stage:Stage IV, dead, 98 days	1311.8
TCGA-ZF-A9R0-01A	82 years, male, white, stage:Stage III, dead, 680 days	1292.0
TCGA-CF-A47T-01A	58 years, female, asian, stage:Stage II, dead, 385 days	1246.7
TCGA-GU-AATO-01A	75 years, male, white, stage:Stage IV, dead, 324 days	1233.6
TCGA-GU-A42Q-01A	67 years, male, white, stage:Stage III, dead, 344 days	1228.0
TCGA-UY-A78K-01A	60 years, male, white, stage:Stage IV, dead, 536 days	1195.5
TCGA-XF-A9T2-01A	54 years, male, white, stage:Stage III, dead, 575 days	1157.9
TCGA-XF-A8HI-01A	57 years, female, white, stage:Stage IV, dead, 544 days	1157.1
TCGA-FD-A3SS-01A	66 years, male, white, stage:Stage IV, dead, 391 days	1124.2
TCGA-FJ-A3ZE-01A	65 years, male, white, stage:Stage IV, dead, 324 days	1062.6
TCGA-DK-A3IQ-01A	74 years, male, white, stage:Stage III, dead, 539 days	1050.0
TCGA-ZF-A9R3-01A	53 years, female, white, stage:Stage II, dead, 949 days	1029.3
TCGA-XF-AAMJ-01A	70 years, male, asian, stage:Stage III, dead, 1670 days	1001.1
TCGA-ZF-AA4T-01A	65 years, male, white, stage:Stage IV, dead, 599 days	986.1
TCGA-FD-A62O-01A	74 years, male, white, stage:Stage IV, dead, 216 days	985.5
TCGA-YC-A9TC-01A	71 years, male, white, stage:Stage IV, dead, 20 days	981.5
TCGA-GV-A40E-01A	75 years, male, white, stage:Stage II, dead, 261 days	981.3
TCGA-GV-A3JV-01A	66 years, male, white, stage:Stage IV, dead, 434 days	953.4
TCGA-FJ-A3Z9-01A	72 years, male, white, stage:'--, dead, 385 days	952.6
TCGA-XF-A8HC-01A	79 years, male, asian, stage:Stage IV, dead, 200 days	933.7
TCGA-BT-A20Q-01A	73 years, male, white, stage:Stage IV, dead, 593 days	924.1
TCGA-5N-A9KM-01A	73 years, female, white, stage:Stage III, dead, 530 days	915.4
TCGA-XF-AAN1-01A	75 years, female, stage:Stage III, dead, 941 days	909.8
TCGA-GC-A3I6-01A	45 years, male, white, stage:Stage III, dead, 630 days	898.7
TCGA-FD-A3B5-01A	86 years, male, black or african american, stage:Stage IV, dead, 272 days	896.0
TCGA-4Z-AA7R-01A	73 years, male, black or african american, stage:Stage IV, dead, 522 days	889.8
TCGA-FD-A3SM-01A	70 years, male, white, stage:Stage IV, dead, 547 days	855.7
TCGA-FD-A5C0-01A	61 years, male, white, stage:Stage IV, dead, 550 days	834.8
TCGA-SY-A9G0-01A	82 years, male, white, stage:Stage IV, dead, 1008 days	819.0
TCGA-FD-A3SL-01A	60 years, male, white, stage:Stage IV, dead, 712 days	813.4
TCGA-XF-A9SL-01A	69 years, male, white, stage:Stage IV, dead, 2020 days	808.4
TCGA-ZF-AA4R-01A	67 years, male, white, stage:Stage IV, dead, 1036 days	805.3
TCGA-5N-A9KI-01A	76 years, female, white, stage:Stage III, dead, 76 days	789.7
TCGA-GV-A3QH-01A	67 years, male, white, stage:Stage II, dead, 258 days	784.3
TCGA-XF-A9SZ-01A	79 years, male, white, stage:Stage IV, dead, 859 days	772.5
TCGA-DK-AA6Q-01A	61 years, female, white, stage:Stage IV, dead, 413 days	767.9
TCGA-FD-A6TI-01A	73 years, male, white, stage:Stage IV, dead, 294 days	767.9
TCGA-XF-AAML-01A	75 years, male, white, stage:Stage II, dead, 232 days	766.2
TCGA-E5-A4TZ-01A	64 years, male, white, stage:Stage IV, dead, 467 days	761.1
TCGA-S5-A6DX-01A	83 years, male, white, stage:Stage IV, dead, 56 days	751.5
TCGA-FD-A6TD-01A	77 years, male, white, stage:Stage III, dead, 386 days	743.2
TCGA-XF-A9SK-01A	65 years, male, white, stage:Stage IV, dead, 486 days	733.0
TCGA-G2-A2EO-01A	69 years, male, white, stage:Stage III, dead, 1804 days	715.0
TCGA-4Z-AA7N-01A	65 years, male, white, stage:Stage III, dead, 1367 days	711.6
TCGA-ZF-AA5N-01A	62 years, female, white, stage:Stage IV, dead, 168 days	709.4
TCGA-XF-AAMT-01A	75 years, female, white, stage:Stage IV, dead, 90 days	696.0
TCGA-XF-A9SP-01A	59 years, male, white, stage:Stage III, dead, 454 days	693.7
TCGA-FD-A6TG-01A	73 years, male, white, stage:Stage IV, dead, 93 days	691.4
TCGA-BT-A20X-01A	56 years, male, white, stage:Stage IV, dead, 251 days	686.2
TCGA-ZF-A9RE-01A	78 years, female, white, stage:Stage II, dead, 106 days	685.4
TCGA-DK-A3IK-01A	87 years, male, white, stage:Stage IV, dead, 146 days	684.8
TCGA-FD-A6TH-01A	63 years, male, white, stage:Stage IV, dead, 131 days	674.1
TCGA-CF-A9FL-01A	85 years, male, asian, stage:Stage III, dead, 565 days	673.4
TCGA-FD-A3SJ-01A	59 years, male, white, stage:Stage IV, dead, 739 days	669.2
TCGA-DK-A3IU-01A	58 years, male, white, stage:Stage II, dead, 706 days	668.8
TCGA-FD-A62S-01A	60 years, female, black or african american, stage:Stage III, dead, 406 days	662.2
TCGA-FD-A3N5-01A	69 years, male, black or african american, stage:Stage II, dead, 685 days	658.5
TCGA-XF-A9T8-01A	64 years, male, white, stage:Stage III, dead, 418 days	656.5
TCGA-XF-AAN0-01A	68 years, male, white, stage:Stage IV, dead, 1718 days	651.7
TCGA-XF-AAMH-01A	80 years, male, white, stage:Stage IV, dead, 344 days	649.1
TCGA-G2-A2EC-01A	58 years, female, black or african american, stage:Stage II, dead, 696 days	636.0
TCGA-XF-A8HH-01A	61 years, female, white, stage:Stage IV, dead, 57 days	632.9
TCGA-G2-AA3C-01A	66 years, male, white, stage:Stage IV, dead, 211 days	615.6
TCGA-E7-A3X6-01A	70 years, male, white, stage:Stage II, dead, 904 days	604.6
TCGA-DK-A1A5-01A	79 years, male, white, stage:Stage II, dead, 65 days	600.1
TCGA-DK-A3IM-01A	76 years, male, white, stage:Stage III, dead, 248 days	595.6
TCGA-ZF-AA56-01A	79 years, female, white, stage:Stage III, dead, 259 days	589.8
TCGA-CU-A72E-01A	76 years, male, white, stage:Stage IV, dead, 413 days	587.8
TCGA-FD-A43Y-01A	65 years, male, white, stage:Stage III, dead, 474 days	582.1
TCGA-XF-A9ST-01A	68 years, male, white, stage:Stage III, dead, 128 days	570.0
TCGA-FD-A6TF-01A	80 years, female, white, stage:Stage IV, dead, 69 days	568.3
TCGA-BT-A20U-01A	70 years, female, white, stage:Stage III, dead, 455 days	561.2
TCGA-BT-A2LD-01A	78 years, female, white, stage:Stage IV, dead, 623 days	560.4
TCGA-FJ-A871-01A	49 years, male, white, stage:Stage III, dead, 272 days	557.1
TCGA-K4-A4AC-01A	83 years, male, white, stage:Stage II, dead, 278 days	553.5
TCGA-XF-AAN7-01A	60 years, male, white, stage:Stage IV, dead, 565 days	553.4
TCGA-GV-A3QF-01A	79 years, male, white, stage:Stage IV, dead, 617 days	545.1
TCGA-FD-A62P-01A	76 years, male, white, stage:Stage II, dead, 191 days	545.0
TCGA-CU-A5W6-01A	70 years, male, white, stage:Stage III, dead, 56 days	540.9
TCGA-BT-A2LB-01A	73 years, female, white, stage:Stage III, dead, 492 days	540.4
TCGA-2F-A9KO-01A	63 years, male, white, stage:Stage IV, dead, 734 days	539.2
TCGA-FD-A3B4-01A	55 years, female, black or african american, stage:Stage III, dead, 510 days	538.3
TCGA-HQ-A5NE-01A	57 years, male, stage:Stage III, dead, 370 days	534.8
TCGA-XF-AAN2-01A	73 years, male, white, stage:Stage II, dead, 1869 days	531.9
TCGA-FD-A5BT-01A	84 years, male, white, stage:Stage III, dead, 328 days	530.9
TCGA-XF-A8HG-01A	69 years, male, white, stage:Stage III, dead, 467 days	518.2
TCGA-2F-A9KP-01A	66 years, male, white, stage:Stage IV, dead, 364 days	509.7
TCGA-FD-A3SQ-01A	62 years, male, white, stage:Stage IV, dead, 1423 days	503.0
TCGA-BT-A20V-01A	59 years, female, black or african american, stage:Stage IV, dead, 154 days	499.3
TCGA-E7-A97P-01A	73 years, male, asian, stage:Stage II, dead, 437 days	497.3
TCGA-GU-A762-01A	87 years, male, white, stage:Stage IV, dead, 232 days	495.8
TCGA-G2-A3IB-01A	66 years, male, black or african american, stage:Stage II, dead, 220 days	493.4
TCGA-XF-AAME-01A	64 years, female, white, stage:Stage II, dead, 2828 days	481.8
TCGA-C4-A0F7-01A	77 years, male, stage:Stage IV, dead, 62 days	474.2
TCGA-BT-A3PK-01A	80 years, male, white, stage:Stage II, dead, 303 days	471.2
TCGA-ZF-A9RN-01A	67 years, female, white, stage:Stage III, dead, 615 days	468.2
TCGA-DK-A1A3-01A	60 years, male, white, stage:Stage IV, dead, 665 days	467.3
TCGA-FD-A5BV-01A	47 years, female, white, stage:Stage III, dead, 163 days	453.6
TCGA-FD-A3B3-01A	74 years, female, white, stage:Stage III, dead, 974 days	449.8
TCGA-XF-A9SH-01A	65 years, female, asian, stage:Stage II, dead, 1971 days	447.9
TCGA-GC-A3BM-01A	70 years, male, white, stage:Stage II, dead, 651 days	446.6
TCGA-BT-A20W-01A	71 years, male, white, stage:Stage II, dead, 254 days	439.0
TCGA-E7-A4XJ-01A	66 years, male, asian, stage:Stage II, dead, 68 days	422.1
TCGA-XF-A9SW-01A	85 years, male, white, stage:Stage IV, dead, 362 days	415.5
TCGA-GU-A42R-01A	68 years, male, white, stage:Stage IV, dead, 577 days	414.4
TCGA-FD-A3SR-01A	68 years, male, white, stage:Stage IV, dead, 602 days	413.5
TCGA-FD-A3B6-01A	75 years, male, white, stage:Stage II, dead, 1005 days	413.3
TCGA-DK-AA6W-01A	78 years, male, white, stage:Stage II, dead, 415 days	400.7
TCGA-GU-AATQ-01A	68 years, male, white, stage:Stage III, dead, 213 days	386.4
TCGA-XF-AAN4-01A	77 years, female, white, stage:Stage III, dead, 823 days	385.3
TCGA-CU-A0YO-01A	84 years, male, white, stage:Stage IV, dead, 149 days	384.5
TCGA-BT-A3PH-01A	76 years, male, white, stage:Stage IV, dead, 142 days	382.3
TCGA-4Z-AA86-01A	66 years, male, black or african american, stage:Stage IV, dead, 311 days	375.7
TCGA-FD-A3SO-01A	68 years, male, white, stage:Stage IV, dead, 168 days	365.2
TCGA-K4-A5RI-01A	67 years, female, white, stage:Stage III, dead, 356 days	363.6
TCGA-BT-A20O-01A	75 years, male, white, stage:Stage III, dead, 370 days	357.4
TCGA-BL-A3JM-01A	62 years, male, white, stage:Stage III, dead, 205 days	354.6
TCGA-ZF-AA4N-01A	74 years, male, white, stage:Stage II, dead, 88 days	353.0
TCGA-XF-AAMW-01A	79 years, female, white, stage:Stage IV, dead, 253 days	350.4
TCGA-ZF-A9RD-01A	75 years, female, white, stage:Stage IV, dead, 408 days	349.6
TCGA-4Z-AA7Q-01A	79 years, male, white, stage:Stage III, dead, 510 days	344.5
TCGA-G2-A2EL-01A	77 years, male, white, stage:Stage II, dead, 819 days	340.4
TCGA-XF-AAN8-01A	74 years, female, white, stage:Stage III, dead, 118 days	337.2
TCGA-HQ-A5ND-01A	78 years, male, stage:Stage IV, dead, 274 days	323.7
TCGA-DK-A1AB-01A	74 years, female, white, stage:Stage IV, dead, 508 days	312.5
TCGA-BT-A0YX-01A	70 years, female, white, stage:Stage III, dead, 400 days	310.0
TCGA-BT-A20J-01A	75 years, male, white, stage:Stage II, dead, 579 days	307.8
TCGA-CU-A0YN-01A	60 years, male, white, stage:Stage III, dead, 393 days	306.3
TCGA-BT-A0S7-01A	75 years, male, white, stage:Stage III, dead, 200 days	305.5
TCGA-FD-A5BX-01A	82 years, male, white, stage:Stage IV, dead, 173 days	278.3
TCGA-FD-A3B7-01A	66 years, male, black or african american, stage:Stage III, dead, 122 days	277.1
TCGA-4Z-AA82-01A	59 years, male, black or african american, stage:Stage IV, dead, 1556 days	276.0
TCGA-G2-A2ES-01A	85 years, male, white, stage:Stage II, dead, 1004 days	275.1
TCGA-CU-A0YR-01A	83 years, male, white, stage:Stage IV, dead, 460 days	267.5
TCGA-C4-A0EZ-01A	69 years, female, stage:Stage IV, dead, 273 days	216.9
TCGA-ZF-AA54-01A	71 years, male, white, stage:Stage III, dead, 590 days	213.5
TCGA-BT-A20N-01A	72 years, male, stage:Stage III, dead, 795 days	186.5
TCGA-DK-A2I2-01A	63 years, female, white, stage:Stage IV, dead, 237 days	186.4
TCGA-2F-A9KW-01A	67 years, female, white, stage:Stage III, dead, 254 days	118.8
TCGA-BL-A13J-01A	65 years, male, white, stage:Stage IV, dead, 81 days	109.0
TCGA-BL-A13I-01A	57 years, female, white, stage:Stage III, dead, 223 days	102.1
Show allShow less

UROTHELIAL CANCER - Protein expressionⁱ

Pending cancer tissue analysis