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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
22.2
nTPM
HPA:
11.9
nTPM
GTEx:
22.2
nTPM
FANTOM5:
40.9
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA039666
Cholangiocytes
Medium
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
11.9
Female, age 60
Liver sample 21 nTPM: 12.4
Male, age 54
Liver sample 23 nTPM: 17.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 19
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 11.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 12.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 5.3
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 11.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 12
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 11.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 5.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
22.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 22.2
Samples: 226
Max nTPM: 58.4
Min nTPM: 8.7
Std nTPM: 7.1
Median nTPM: 20.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
58.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
47.4
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
44.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
42.9
GTEX-14PJO-1726-SM-68719
60-69 years, male
42.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
40.5
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
40.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
39.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
38.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
38.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
37.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
35.8
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
35.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
35.1
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
34.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
34.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
34.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
33.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
33.0
GTEX-14XAO-0226-SM-68728
60-69 years, female
32.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
32.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
32.2
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
32.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
31.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
30.7
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
30.1
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
29.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
29.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
29.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
29.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
28.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
28.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
28.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
28.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
28.6
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
28.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
28.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
28.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
28.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
28.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
28.4
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
28.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
27.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
27.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
27.6
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
27.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
27.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
27.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
26.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
26.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
25.9
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
25.9
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
25.8
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
25.7
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
25.5
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
25.5
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
25.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
25.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
25.1
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
25.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
24.8
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
24.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
24.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
24.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
24.4
GTEX-O5YV-0726-SM-EV798
60-69 years, female
24.3
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
24.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
24.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
24.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
24.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
23.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
23.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
23.6
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
23.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
23.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
23.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
23.4
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
23.2
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
23.0
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
22.9
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
22.9
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
22.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
22.7
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
22.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
22.6
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
22.5
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
22.5
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
22.5
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
22.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
22.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
22.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
22.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
22.3
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
22.2
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
22.2
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
21.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
21.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
21.5
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
21.5
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
21.4
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
21.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
21.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
21.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
21.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
21.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
21.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
20.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
20.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
20.8
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
20.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
20.7
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
20.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
20.6
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
20.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
20.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
20.4
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
20.3
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
20.3
GTEX-14E7W-1526-SM-6871X
70-79 years, male
20.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
20.3
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
20.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
20.3
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
20.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
20.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
20.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
20.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
20.0
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
20.0
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
19.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
19.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
19.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
19.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
19.7
GTEX-P78B-1326-SM-3P611
40-49 years, female
19.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
19.6
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
19.6
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
19.6
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
19.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
19.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
19.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
18.9
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
18.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
18.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
18.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
18.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
18.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
18.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
18.4
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
18.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
18.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
18.1
GTEX-14PHX-0526-SM-664NW
50-59 years, male
18.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
18.1
GTEX-RN64-1826-SM-48FDV
50-59 years, male
18.1
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
18.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
18.0
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
18.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
17.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
17.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
17.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
17.9
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
17.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
17.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
17.7
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
17.7
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
17.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
17.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
17.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
17.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
17.3
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
17.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
17.2
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
17.2
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
17.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
17.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
17.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
16.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
16.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
16.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
16.5
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
16.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
16.4
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
16.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
16.3
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
16.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
16.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
16.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
16.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
16.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
16.0
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
15.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
15.9
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
15.8
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
15.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
15.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
15.6
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
15.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
15.5
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
15.4
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
15.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
15.4
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
15.3
GTEX-1B933-1226-SM-731DW
50-59 years, female
15.2
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
15.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
15.0
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
15.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
14.9
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
14.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
14.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
14.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
14.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
13.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
13.8
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
13.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
13.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
13.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
13.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
13.6
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
13.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
13.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
12.9
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
12.8
GTEX-17HHE-0126-SM-79398
50-59 years, male
12.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
12.1
GTEX-Q734-0326-SM-48U15
40-49 years, female
11.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
8.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
