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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:102.9 nTPM
HPA Brain:130.0 nTPM
GTEx:102.9 nTPM
FANTOM5:169.1 Scaled Tags Per Million
Pig:88.8 nTPM
Mouse:38.6 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

130.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 119.9
2019 Male, age 18, unknown 135.8
1870 Female, age 42, unknown 129.7
2666 Male, age 74, left hemisphere 128.7
1830 Male, age 51, unknown 128.2
1833 Male, age 53, unknown 128.0
2411 Female, age 72, unknown 121.9
1827 Male, age 72, unknown 113.4
2828 Female, age 72, unknown 110.0
2219 Male, age 76, both hemispheres 103.1
2586 Male, age 75, left hemisphere 100.0
Dorsal raphe nucleus
nTPM: 115.9
2016 Female, age 72, unknown 127.6
2750 Male, age 76, both hemispheres 127.2
1828 Male, age 53, unknown 114.8
2298 Female, age 72, unknown 106.7
2047 Male, age 72, unknown 103.1
Inferior colliculus
nTPM: 110.8
2097 Female, age 72, unknown 118.2
1890 Male, age 53, unknown 114.1
1848 Female, age 42, unknown 105.4
2849 Male, age 72, unknown 105.3
Median raphe nucleus
nTPM: 126.7
2220 Male, age 76, midline 126.7
Periaquaductal grey, anterior
nTPM: 112.5
2502 Female, age 75, unknown 120.6
1947 Male, age 18, unknown 118.9
1795 Male, age 51, unknown 98.0
Periaquaductal grey, dorsal
nTPM: 117.8
2850 Male, age 76, both hemispheres 124.3
1831 Male, age 72, unknown 120.1
2464 Female, age 72, unknown 117.2
1840 Male, age 53, unknown 109.8
Periaquaductal grey, lateral
nTPM: 111.6
2272 Male, age 74, both hemispheres 115.0
2053 Male, age 18, unknown 110.1
2140 Male, age 76, both hemispheres 109.5
Pretectal area
nTPM: 121.1
1944 Female, age 72, unknown 147.5
1815 Male, age 53, unknown 134.3
1816 Male, age 51, unknown 134.2
1817 Female, age 42, unknown 129.7
2273 Male, age 74, both hemispheres 124.0
2007 Male, age 72, unknown 117.3
2825 Male, age 18, unknown 111.0
2316 Male, age 76, right hemisphere 110.3
2667 Female, age 75, unknown 108.9
2224 Female, age 72, unknown 107.7
2407 Male, age 75, both hemispheres 107.4
Red nucleus
nTPM: 130.0
2503 Female, age 72, unknown 144.2
1865 Male, age 51, unknown 141.7
1821 Female, age 72, unknown 139.5
1904 Male, age 53, unknown 139.3
1954 Female, age 42, unknown 136.2
2823 Male, age 76, right hemisphere 129.7
2725 Female, age 75, unknown 127.2
2785 Male, age 18, unknown 123.9
2227 Male, age 72, unknown 123.1
2769 Male, age 72, unknown 121.6
2588 Male, age 74, left hemisphere 120.5
2584 Male, age 75, left hemisphere 113.6
Substantia nigra
nTPM: 116.6
2241 Male, age 72, unknown 131.7
2409 Female, age 72, unknown 128.0
1889 Female, age 72, unknown 122.8
2665 Male, age 74, both hemispheres 121.4
2699 Male, age 18, unknown 118.9
2590 Female, age 75, unknown 116.9
1941 Male, age 53, unknown 109.2
2583 Male, age 75, right hemisphere 107.1
1851 Male, age 51, unknown 106.8
1916 Female, age 42, unknown 103.1
Superior colliculus
nTPM: 121.7
1995 Male, age 72, unknown 149.0
1913 Female, age 42, unknown 143.9
2087 Female, age 72, unknown 126.6
2668 Female, age 75, unknown 125.8
2587 Male, age 74, left hemisphere 124.9
1895 Male, age 76, right hemisphere 114.3
1839 Male, age 51, unknown 113.8
2261 Male, age 18, unknown 112.3
1796 Male, age 53, unknown 106.4
2664 Male, age 75, both hemispheres 99.5
Ventral tegmental area
nTPM: 108.1
2223 Female, age 72, unknown 120.4
1942 Male, age 51, unknown 109.0
2021 Male, age 53, unknown 106.0
2218 Male, age 76, both hemispheres 105.9
2410 Female, age 72, unknown 104.2
1915 Female, age 42, unknown 103.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

102.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 102.9
Samples: 139

Max nTPM: 216.6
Min nTPM: 48.0
Std nTPM: 30.7
Median nTPM: 97.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 216.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 194.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 178.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 177.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 164.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 162.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 160.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 160.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 158.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 158.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 157.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 155.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 146.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 146.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 146.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 144.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 141.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 141.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 140.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 140.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 138.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 134.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 134.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 133.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 133.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 131.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 123.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 122.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 122.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 122.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 119.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 118.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 118.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 118.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 117.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 117.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 117.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 116.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 116.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 116.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 114.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 113.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 113.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 113.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 112.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 112.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 111.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 111.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 111.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 111.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 110.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 110.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 108.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 108.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 106.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 106.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 105.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 104.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 103.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 103.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 102.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 101.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 101.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 101.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 101.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 99.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 98.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 98.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 97.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 97.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 96.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 96.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 95.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 95.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 94.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 93.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 93.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 92.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 91.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 91.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 91.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 91.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 91.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 91.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 90.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 89.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 89.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 87.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 87.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 87.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 86.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 85.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 85.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 85.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 84.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 83.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 83.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 83.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 83.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 83.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 81.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 80.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 80.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 80.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 79.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 79.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 79.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 78.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 78.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 78.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 77.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 77.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 77.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 76.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 76.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 76.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 75.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 75.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 73.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 73.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 72.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 72.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 72.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 72.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 71.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 70.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 68.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 68.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 66.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 64.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 64.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 64.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 62.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 61.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 56.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 54.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 52.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 50.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 48.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

169.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 169.1
FF:10158-103A5 76 years, female 169.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

88.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 79.1
Samples: 4

Max nTPM: 92.8
Min nTPM: 69.0
Sample A Female 80.7
Sample B Female 69.0
Sample C Male 73.7
Sample D Male 92.8
Midbrain
nTPM: 88.8
Samples: 4

Max nTPM: 143.4
Min nTPM: 61.9
Sample A Female 143.4
Sample B Female 82.5
Sample C Male 67.3
Sample D Male 61.9
Periaqueductal gray
nTPM: 63.9
Samples: 3

Max nTPM: 70.8
Min nTPM: 60.0
Sample B Female 60.0
Sample C Male 61.0
Sample D Male 70.8
Superior colliculi
nTPM: 71.8
Samples: 4

Max nTPM: 78.6
Min nTPM: 59.7
Sample A Female 74.2
Sample B Female 59.7
Sample C Male 74.8
Sample D Male 78.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

38.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 38.6
Samples: 4

Max nTPM: 44.0
Min nTPM: 35.4
Sample A Male 35.4
Sample B Male 37.3
Sample C Female 44.0
Sample D Female 37.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
74635451 Antisense, RP_060215_03_H05, Mouse strain C57BL/6J (56 days, male) 0.7

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