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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:54.7 nTPM
HPA Brain:188.1 nTPM
GTEx:54.7 nTPM
FANTOM5:6.1 Scaled Tags Per Million
Pig:60.7 nTPM
Mouse:44.8 nTPM
Allen mouse:11.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

188.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 116.6
2666 Male, age 74, left hemisphere 164.0
2828 Female, age 72, unknown 152.5
1827 Male, age 72, unknown 148.7
2219 Male, age 76, both hemispheres 145.2
2586 Male, age 75, left hemisphere 131.8
2411 Female, age 72, unknown 115.9
1870 Female, age 42, unknown 89.9
2019 Male, age 18, unknown 78.4
1833 Male, age 53, unknown 73.6
1830 Male, age 51, unknown 65.9
Dorsal raphe nucleus
nTPM: 123.3
2298 Female, age 72, unknown 167.0
2750 Male, age 76, both hemispheres 146.9
2047 Male, age 72, unknown 135.3
1828 Male, age 53, unknown 94.6
2016 Female, age 72, unknown 72.8
Inferior colliculus
nTPM: 69.8
2097 Female, age 72, unknown 88.6
1848 Female, age 42, unknown 68.9
1890 Male, age 53, unknown 62.7
2849 Male, age 72, unknown 58.9
Median raphe nucleus
nTPM: 188.1
2220 Male, age 76, midline 188.1
Periaquaductal grey, anterior
nTPM: 165.8
1795 Male, age 51, unknown 209.1
2502 Female, age 75, unknown 149.4
1947 Male, age 18, unknown 139.1
Periaquaductal grey, dorsal
nTPM: 85.2
1840 Male, age 53, unknown 96.3
1831 Male, age 72, unknown 86.7
2850 Male, age 76, both hemispheres 82.4
2464 Female, age 72, unknown 75.6
Periaquaductal grey, lateral
nTPM: 76.2
2053 Male, age 18, unknown 94.6
2140 Male, age 76, both hemispheres 77.3
2272 Male, age 74, both hemispheres 56.9
Pretectal area
nTPM: 136.6
1816 Male, age 51, unknown 226.3
1944 Female, age 72, unknown 185.5
2667 Female, age 75, unknown 178.1
2007 Male, age 72, unknown 176.6
1815 Male, age 53, unknown 166.3
1817 Female, age 42, unknown 164.2
2224 Female, age 72, unknown 119.9
2825 Male, age 18, unknown 102.0
2316 Male, age 76, right hemisphere 74.3
2407 Male, age 75, both hemispheres 60.1
2273 Male, age 74, both hemispheres 49.3
Red nucleus
nTPM: 55.4
2584 Male, age 75, left hemisphere 116.7
2785 Male, age 18, unknown 89.5
2588 Male, age 74, left hemisphere 56.0
1954 Female, age 42, unknown 55.2
1821 Female, age 72, unknown 53.2
2769 Male, age 72, unknown 50.5
2227 Male, age 72, unknown 49.4
1904 Male, age 53, unknown 47.0
2503 Female, age 72, unknown 44.8
2823 Male, age 76, right hemisphere 40.6
1865 Male, age 51, unknown 39.2
2725 Female, age 75, unknown 23.1
Substantia nigra
nTPM: 144.7
2665 Male, age 74, both hemispheres 240.6
1916 Female, age 42, unknown 212.9
1941 Male, age 53, unknown 161.7
1851 Male, age 51, unknown 160.2
1889 Female, age 72, unknown 158.8
2241 Male, age 72, unknown 127.6
2583 Male, age 75, right hemisphere 119.7
2409 Female, age 72, unknown 112.2
2699 Male, age 18, unknown 95.1
2590 Female, age 75, unknown 58.3
Superior colliculus
nTPM: 138.8
2668 Female, age 75, unknown 437.3
1796 Male, age 53, unknown 161.1
2087 Female, age 72, unknown 159.5
2261 Male, age 18, unknown 149.3
2664 Male, age 75, both hemispheres 104.3
1913 Female, age 42, unknown 84.2
1839 Male, age 51, unknown 83.8
1895 Male, age 76, right hemisphere 73.9
2587 Male, age 74, left hemisphere 67.6
1995 Male, age 72, unknown 66.8
Ventral tegmental area
nTPM: 133.5
2218 Male, age 76, both hemispheres 181.3
1915 Female, age 42, unknown 151.1
2410 Female, age 72, unknown 150.5
1942 Male, age 51, unknown 137.6
2021 Male, age 53, unknown 112.3
2223 Female, age 72, unknown 68.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

54.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 54.7
Samples: 139

Max nTPM: 231.9
Min nTPM: 0.7
Std nTPM: 55.3
Median nTPM: 35.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 231.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 227.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 207.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 197.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 197.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 193.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 181.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 173.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 167.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 160.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 153.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 146.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 140.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 134.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 121.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 121.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 120.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 119.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 119.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 112.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 111.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 110.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 109.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 103.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 97.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 94.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 92.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 92.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 90.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 90.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 90.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 90.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 89.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 87.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 87.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 85.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 84.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 83.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 82.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 82.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 80.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 79.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 78.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 75.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 72.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 72.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 67.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 66.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 65.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 65.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 64.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 62.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 60.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 58.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 55.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 54.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 53.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 51.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 50.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 50.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 50.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 50.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 50.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 48.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 48.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 44.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 41.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 38.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 35.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 35.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 33.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 32.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 30.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 30.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 26.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 26.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 24.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 23.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 22.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 22.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 21.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 21.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 20.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 19.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 16.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 16.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 15.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 15.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 15.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 14.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 14.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 14.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 14.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 13.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 13.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 13.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 13.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 12.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 12.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 11.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 11.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 11.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 10.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 10.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 9.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 7.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 7.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 7.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 6.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 6.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 6.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 6.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 6.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 5.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 5.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 5.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 5.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 5.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 4.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 4.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 4.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 4.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 4.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 4.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 3.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 2.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 2.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 0.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 0.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

6.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 6.1
FF:10158-103A5 76 years, female 6.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

60.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 60.7
Samples: 4

Max nTPM: 103.1
Min nTPM: 9.2
Sample A Female 89.3
Sample B Female 41.2
Sample C Male 103.1
Sample D Male 9.2
Midbrain
nTPM: 50.0
Samples: 4

Max nTPM: 117.0
Min nTPM: 4.6
Sample A Female 4.6
Sample B Female 31.8
Sample C Male 117.0
Sample D Male 46.4
Periaqueductal gray
nTPM: 28.1
Samples: 3

Max nTPM: 43.1
Min nTPM: 18.2
Sample B Female 22.9
Sample C Male 43.1
Sample D Male 18.2
Superior colliculi
nTPM: 36.9
Samples: 4

Max nTPM: 62.3
Min nTPM: 15.3
Sample A Female 33.1
Sample B Female 15.3
Sample C Male 62.3
Sample D Male 36.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 44.8
Samples: 4

Max nTPM: 65.3
Min nTPM: 29.4
Sample A Male 65.3
Sample B Male 43.9
Sample C Female 29.4
Sample D Female 40.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

11.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.9
1861 Antisense, RP_040526_02_E02, Mouse strain C57BL/6J (56 days, male) 11.9
1860 Antisense, RP_040526_02_E02, Mouse strain C57BL/6J (56 days, male) 4.4

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