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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:23.6 nTPM
HPA Brain:59.7 nTPM
GTEx:23.6 nTPM
FANTOM5:2.1 Scaled Tags Per Million
Pig:83.5 nTPM
Mouse:261.9 nTPM
Allen mouse:14.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

59.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 44.4
2666 Male, age 74, left hemisphere 62.4
2219 Male, age 76, both hemispheres 55.9
1827 Male, age 72, unknown 53.6
2411 Female, age 72, unknown 52.4
1870 Female, age 42, unknown 39.5
2586 Male, age 75, left hemisphere 39.2
2019 Male, age 18, unknown 38.0
1833 Male, age 53, unknown 35.5
2828 Female, age 72, unknown 35.4
1830 Male, age 51, unknown 32.3
Dorsal raphe nucleus
nTPM: 46.1
2298 Female, age 72, unknown 56.1
1828 Male, age 53, unknown 51.7
2047 Male, age 72, unknown 49.6
2750 Male, age 76, both hemispheres 43.5
2016 Female, age 72, unknown 29.7
Inferior colliculus
nTPM: 46.8
2097 Female, age 72, unknown 57.2
1848 Female, age 42, unknown 46.3
1890 Male, age 53, unknown 44.2
2849 Male, age 72, unknown 39.6
Median raphe nucleus
nTPM: 59.7
2220 Male, age 76, midline 59.7
Periaquaductal grey, anterior
nTPM: 52.6
1947 Male, age 18, unknown 57.1
1795 Male, age 51, unknown 53.1
2502 Female, age 75, unknown 47.6
Periaquaductal grey, dorsal
nTPM: 34.6
1840 Male, age 53, unknown 38.8
2464 Female, age 72, unknown 33.3
2850 Male, age 76, both hemispheres 33.3
1831 Male, age 72, unknown 33.0
Periaquaductal grey, lateral
nTPM: 28.0
2053 Male, age 18, unknown 33.2
2140 Male, age 76, both hemispheres 28.7
2272 Male, age 74, both hemispheres 22.2
Pretectal area
nTPM: 48.6
1816 Male, age 51, unknown 74.4
1944 Female, age 72, unknown 73.6
2007 Male, age 72, unknown 61.3
2667 Female, age 75, unknown 59.8
1817 Female, age 42, unknown 58.8
1815 Male, age 53, unknown 47.6
2224 Female, age 72, unknown 46.8
2825 Male, age 18, unknown 40.4
2316 Male, age 76, right hemisphere 31.9
2407 Male, age 75, both hemispheres 22.3
2273 Male, age 74, both hemispheres 18.0
Red nucleus
nTPM: 35.1
1821 Female, age 72, unknown 55.3
1954 Female, age 42, unknown 40.7
2785 Male, age 18, unknown 37.0
2769 Male, age 72, unknown 36.3
2227 Male, age 72, unknown 36.1
2584 Male, age 75, left hemisphere 35.8
2503 Female, age 72, unknown 34.3
2823 Male, age 76, right hemisphere 33.1
1865 Male, age 51, unknown 31.8
1904 Male, age 53, unknown 31.8
2588 Male, age 74, left hemisphere 29.0
2725 Female, age 75, unknown 19.5
Substantia nigra
nTPM: 58.5
1916 Female, age 42, unknown 83.7
2665 Male, age 74, both hemispheres 82.7
1941 Male, age 53, unknown 63.1
1889 Female, age 72, unknown 61.9
1851 Male, age 51, unknown 61.0
2409 Female, age 72, unknown 59.7
2241 Male, age 72, unknown 57.0
2699 Male, age 18, unknown 42.2
2583 Male, age 75, right hemisphere 38.9
2590 Female, age 75, unknown 35.1
Superior colliculus
nTPM: 44.8
2668 Female, age 75, unknown 93.4
2087 Female, age 72, unknown 58.9
1796 Male, age 53, unknown 52.2
1895 Male, age 76, right hemisphere 49.5
2261 Male, age 18, unknown 48.9
1839 Male, age 51, unknown 39.6
1913 Female, age 42, unknown 29.6
2664 Male, age 75, both hemispheres 27.8
2587 Male, age 74, left hemisphere 24.1
1995 Male, age 72, unknown 23.5
Ventral tegmental area
nTPM: 53.9
2218 Male, age 76, both hemispheres 72.0
2410 Female, age 72, unknown 71.6
1915 Female, age 42, unknown 64.2
1942 Male, age 51, unknown 42.0
2223 Female, age 72, unknown 37.2
2021 Male, age 53, unknown 36.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 23.6
Samples: 139

Max nTPM: 168.8
Min nTPM: 0.0
Std nTPM: 33.2
Median nTPM: 6.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 168.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 164.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 118.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 113.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 104.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 100.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 95.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 89.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 84.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 82.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 79.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 79.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 78.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 75.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 74.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 66.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 66.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 65.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 63.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 62.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 60.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 59.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 54.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 52.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 52.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 50.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 45.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 45.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 43.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 41.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 38.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 36.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 35.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 35.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 35.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 30.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 30.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 29.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 26.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 26.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 26.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 25.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 24.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 23.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 22.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 21.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 19.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 19.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 19.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 17.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 17.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 16.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 15.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 14.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 14.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 14.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 13.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 13.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 12.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 12.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 11.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 11.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 10.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 10.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 10.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 8.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 8.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 7.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 7.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 6.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 6.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 6.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 6.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 6.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 5.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 5.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 5.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 4.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 4.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 4.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 3.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 3.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 3.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 3.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 3.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 3.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 3.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 3.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 3.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 2.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 2.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 2.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 2.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 2.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 2.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 2.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 0.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 0.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 0.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 0.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 0.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 0.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 0.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 0.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 0.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 0.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 0.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 0.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

2.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2.1
FF:10158-103A5 76 years, female 2.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

83.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 49.3
Samples: 4

Max nTPM: 80.5
Min nTPM: 16.7
Sample A Female 80.5
Sample B Female 34.6
Sample C Male 65.3
Sample D Male 16.7
Midbrain
nTPM: 65.7
Samples: 4

Max nTPM: 124.0
Min nTPM: 16.1
Sample A Female 16.1
Sample B Female 41.8
Sample C Male 124.0
Sample D Male 80.8
Periaqueductal gray
nTPM: 38.8
Samples: 3

Max nTPM: 52.4
Min nTPM: 29.7
Sample B Female 34.3
Sample C Male 52.4
Sample D Male 29.7
Superior colliculi
nTPM: 83.5
Samples: 4

Max nTPM: 128.8
Min nTPM: 44.9
Sample A Female 88.2
Sample B Female 44.9
Sample C Male 128.8
Sample D Male 72.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

261.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 261.9
Samples: 4

Max nTPM: 269.4
Min nTPM: 253.8
Sample A Male 264.0
Sample B Male 260.4
Sample C Female 253.8
Sample D Female 269.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.4
69113650 Antisense, RP_050316_02_E04, Mouse strain C57BL/6J (56 days, male) 14.4

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