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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:94.4 nTPM
HPA Brain:106.9 nTPM
GTEx:94.4 nTPM
FANTOM5:150.7 Scaled Tags Per Million
Pig:132.4 nTPM
Mouse:109.3 nTPM
Allen mouse:7.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

106.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 84.7
2019 Male, age 18, unknown 92.8
2411 Female, age 72, unknown 92.7
1870 Female, age 42, unknown 90.1
2666 Male, age 74, left hemisphere 90.1
2828 Female, age 72, unknown 86.6
1830 Male, age 51, unknown 85.3
1833 Male, age 53, unknown 85.3
1827 Male, age 72, unknown 83.0
2219 Male, age 76, both hemispheres 73.2
2586 Male, age 75, left hemisphere 68.0
Dorsal raphe nucleus
nTPM: 89.2
2750 Male, age 76, both hemispheres 98.9
2298 Female, age 72, unknown 93.2
1828 Male, age 53, unknown 89.3
2016 Female, age 72, unknown 82.8
2047 Male, age 72, unknown 81.8
Inferior colliculus
nTPM: 73.0
2097 Female, age 72, unknown 82.9
1890 Male, age 53, unknown 78.7
1848 Female, age 42, unknown 69.8
2849 Male, age 72, unknown 60.5
Median raphe nucleus
nTPM: 94.1
2220 Male, age 76, midline 94.1
Periaquaductal grey, anterior
nTPM: 86.2
1947 Male, age 18, unknown 96.0
2502 Female, age 75, unknown 82.8
1795 Male, age 51, unknown 79.8
Periaquaductal grey, dorsal
nTPM: 71.7
2850 Male, age 76, both hemispheres 76.3
1831 Male, age 72, unknown 75.8
2464 Female, age 72, unknown 70.6
1840 Male, age 53, unknown 64.0
Periaquaductal grey, lateral
nTPM: 75.2
2272 Male, age 74, both hemispheres 81.5
2053 Male, age 18, unknown 72.5
2140 Male, age 76, both hemispheres 71.6
Pretectal area
nTPM: 83.2
1817 Female, age 42, unknown 94.6
2007 Male, age 72, unknown 92.1
1815 Male, age 53, unknown 88.1
1816 Male, age 51, unknown 84.8
1944 Female, age 72, unknown 84.6
2316 Male, age 76, right hemisphere 82.8
2224 Female, age 72, unknown 81.4
2273 Male, age 74, both hemispheres 80.4
2407 Male, age 75, both hemispheres 77.3
2667 Female, age 75, unknown 76.2
2825 Male, age 18, unknown 73.3
Red nucleus
nTPM: 93.5
1821 Female, age 72, unknown 114.7
1904 Male, age 53, unknown 103.3
1865 Male, age 51, unknown 102.7
2725 Female, age 75, unknown 100.0
1954 Female, age 42, unknown 96.1
2785 Male, age 18, unknown 94.3
2503 Female, age 72, unknown 91.6
2769 Male, age 72, unknown 91.3
2227 Male, age 72, unknown 90.7
2823 Male, age 76, right hemisphere 89.2
2584 Male, age 75, left hemisphere 75.2
2588 Male, age 74, left hemisphere 72.5
Substantia nigra
nTPM: 106.9
1916 Female, age 42, unknown 138.4
1851 Male, age 51, unknown 120.1
2241 Male, age 72, unknown 119.4
2409 Female, age 72, unknown 106.1
2590 Female, age 75, unknown 102.0
2665 Male, age 74, both hemispheres 101.1
2699 Male, age 18, unknown 100.3
1941 Male, age 53, unknown 96.7
1889 Female, age 72, unknown 93.6
2583 Male, age 75, right hemisphere 91.5
Superior colliculus
nTPM: 81.5
2587 Male, age 74, left hemisphere 96.7
1913 Female, age 42, unknown 90.4
2668 Female, age 75, unknown 88.4
1995 Male, age 72, unknown 84.2
1796 Male, age 53, unknown 83.2
2261 Male, age 18, unknown 80.5
2087 Female, age 72, unknown 78.1
1895 Male, age 76, right hemisphere 76.8
1839 Male, age 51, unknown 73.6
2664 Male, age 75, both hemispheres 63.5
Ventral tegmental area
nTPM: 101.4
1915 Female, age 42, unknown 109.9
2410 Female, age 72, unknown 107.1
2223 Female, age 72, unknown 103.8
2218 Male, age 76, both hemispheres 102.2
1942 Male, age 51, unknown 92.6
2021 Male, age 53, unknown 92.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

94.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 94.4
Samples: 139

Max nTPM: 142.9
Min nTPM: 63.8
Std nTPM: 15.3
Median nTPM: 92.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 142.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 131.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 130.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 129.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 128.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 123.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 123.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 123.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 120.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 119.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 117.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 117.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 116.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 115.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 114.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 112.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 112.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 112.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 112.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 111.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 111.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 110.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 110.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 110.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 110.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 109.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 108.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 108.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 107.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 107.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 107.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 106.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 105.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 104.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 103.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 103.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 103.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 103.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 102.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 102.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 102.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 101.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 101.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 101.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 100.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 100.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 100.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 100.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 99.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 99.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 99.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 98.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 98.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 98.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 98.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 97.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 96.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 96.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 96.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 95.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 95.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 94.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 94.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 93.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 93.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 93.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 93.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 92.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 92.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 92.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 91.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 91.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 90.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 90.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 90.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 89.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 89.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 89.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 89.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 88.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 88.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 88.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 88.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 88.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 87.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 87.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 87.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 86.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 86.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 86.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 86.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 86.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 86.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 86.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 85.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 85.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 85.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 85.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 85.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 85.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 84.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 84.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 84.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 83.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 83.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 83.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 83.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 83.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 83.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 83.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 82.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 81.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 80.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 80.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 79.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 79.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 79.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 78.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 78.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 78.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 78.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 77.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 77.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 76.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 76.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 76.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 75.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 75.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 75.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 75.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 73.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 72.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 70.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 70.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 69.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 69.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 64.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 64.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 63.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

150.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 150.7
FF:10158-103A5 76 years, female 150.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

132.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 132.1
Samples: 4

Max nTPM: 153.4
Min nTPM: 118.2
Sample A Female 153.4
Sample B Female 121.9
Sample C Male 135.0
Sample D Male 118.2
Midbrain
nTPM: 132.4
Samples: 4

Max nTPM: 193.2
Min nTPM: 94.3
Sample A Female 193.2
Sample B Female 115.0
Sample C Male 127.0
Sample D Male 94.3
Periaqueductal gray
nTPM: 99.2
Samples: 3

Max nTPM: 107.0
Min nTPM: 91.8
Sample B Female 98.7
Sample C Male 107.0
Sample D Male 91.8
Superior colliculi
nTPM: 128.6
Samples: 4

Max nTPM: 142.4
Min nTPM: 113.8
Sample A Female 138.8
Sample B Female 113.8
Sample C Male 142.4
Sample D Male 119.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

109.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 109.3
Samples: 4

Max nTPM: 115.7
Min nTPM: 105.0
Sample A Male 105.0
Sample B Male 106.7
Sample C Female 115.7
Sample D Female 109.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.8
323396 Antisense, RP_040617_01_A03, Mouse strain C57BL/6J (56 days, male) 8.1
76081921 Antisense, RP_060626_01_A01, Mouse strain C57BL/6J (56 days, male) 7.6

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