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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:294.2 nTPM
HPA Brain:408.5 nTPM
GTEx:294.2 nTPM
FANTOM5:480.6 Scaled Tags Per Million
Pig:304.5 nTPM
Mouse:304.9 nTPM
Allen mouse:10.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

408.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 386.4
2586 Male, age 75, left hemisphere 545.2
2666 Male, age 74, left hemisphere 466.1
2828 Female, age 72, unknown 407.4
1827 Male, age 72, unknown 402.0
1833 Male, age 53, unknown 374.5
1870 Female, age 42, unknown 369.6
1830 Male, age 51, unknown 347.0
2411 Female, age 72, unknown 334.9
2219 Male, age 76, both hemispheres 322.1
2019 Male, age 18, unknown 295.3
Dorsal raphe nucleus
nTPM: 351.9
2047 Male, age 72, unknown 385.3
1828 Male, age 53, unknown 382.0
2750 Male, age 76, both hemispheres 352.5
2298 Female, age 72, unknown 339.5
2016 Female, age 72, unknown 300.4
Inferior colliculus
nTPM: 331.3
2849 Male, age 72, unknown 419.4
1848 Female, age 42, unknown 347.4
1890 Male, age 53, unknown 284.8
2097 Female, age 72, unknown 273.4
Median raphe nucleus
nTPM: 407.6
2220 Male, age 76, midline 407.6
Periaquaductal grey, anterior
nTPM: 394.2
1947 Male, age 18, unknown 423.0
2502 Female, age 75, unknown 384.5
1795 Male, age 51, unknown 375.0
Periaquaductal grey, dorsal
nTPM: 326.6
2850 Male, age 76, both hemispheres 386.9
1840 Male, age 53, unknown 318.7
2464 Female, age 72, unknown 313.7
1831 Male, age 72, unknown 287.0
Periaquaductal grey, lateral
nTPM: 300.3
2053 Male, age 18, unknown 322.7
2140 Male, age 76, both hemispheres 313.6
2272 Male, age 74, both hemispheres 264.7
Pretectal area
nTPM: 344.9
1817 Female, age 42, unknown 403.7
1816 Male, age 51, unknown 392.7
2825 Male, age 18, unknown 390.7
2667 Female, age 75, unknown 384.5
1815 Male, age 53, unknown 366.3
2007 Male, age 72, unknown 349.4
1944 Female, age 72, unknown 339.9
2407 Male, age 75, both hemispheres 326.3
2224 Female, age 72, unknown 310.8
2316 Male, age 76, right hemisphere 286.1
2273 Male, age 74, both hemispheres 243.8
Red nucleus
nTPM: 362.5
1821 Female, age 72, unknown 433.5
2584 Male, age 75, left hemisphere 405.8
2769 Male, age 72, unknown 380.7
2227 Male, age 72, unknown 362.1
1954 Female, age 42, unknown 358.9
2823 Male, age 76, right hemisphere 357.8
1865 Male, age 51, unknown 357.6
2725 Female, age 75, unknown 356.8
2588 Male, age 74, left hemisphere 355.2
1904 Male, age 53, unknown 338.1
2503 Female, age 72, unknown 327.3
2785 Male, age 18, unknown 316.5
Substantia nigra
nTPM: 408.5
1916 Female, age 42, unknown 512.3
1941 Male, age 53, unknown 486.9
2699 Male, age 18, unknown 469.1
1851 Male, age 51, unknown 429.7
2665 Male, age 74, both hemispheres 413.8
2583 Male, age 75, right hemisphere 398.2
1889 Female, age 72, unknown 391.4
2241 Male, age 72, unknown 354.2
2590 Female, age 75, unknown 321.0
2409 Female, age 72, unknown 308.7
Superior colliculus
nTPM: 351.9
2664 Male, age 75, both hemispheres 468.8
2668 Female, age 75, unknown 402.8
1796 Male, age 53, unknown 378.4
1839 Male, age 51, unknown 363.6
2261 Male, age 18, unknown 332.2
2587 Male, age 74, left hemisphere 331.2
1895 Male, age 76, right hemisphere 325.6
2087 Female, age 72, unknown 323.4
1913 Female, age 42, unknown 314.7
1995 Male, age 72, unknown 278.1
Ventral tegmental area
nTPM: 360.7
1915 Female, age 42, unknown 408.6
2410 Female, age 72, unknown 386.8
2223 Female, age 72, unknown 381.0
2218 Male, age 76, both hemispheres 365.5
1942 Male, age 51, unknown 325.9
2021 Male, age 53, unknown 296.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

294.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 294.2
Samples: 139

Max nTPM: 583.7
Min nTPM: 151.6
Std nTPM: 65.3
Median nTPM: 286.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 583.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 464.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 429.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 427.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 425.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 417.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 417.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 412.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 409.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 402.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 398.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 396.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 392.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 387.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 377.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 375.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 368.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 359.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 356.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 353.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 352.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 351.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 351.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 346.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 346.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 343.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 341.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 340.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 340.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 340.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 339.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 338.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 337.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 336.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 336.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 336.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 335.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 332.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 332.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 330.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 328.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 328.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 322.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 320.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 318.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 315.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 315.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 311.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 305.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 304.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 302.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 302.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 296.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 296.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 295.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 295.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 294.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 294.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 292.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 291.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 290.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 290.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 289.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 288.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 288.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 287.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 286.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 286.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 286.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 286.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 285.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 284.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 281.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 280.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 280.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 279.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 279.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 278.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 278.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 277.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 276.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 276.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 276.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 275.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 275.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 275.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 274.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 273.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 270.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 269.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 269.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 269.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 264.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 264.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 264.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 263.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 263.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 263.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 261.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 259.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 259.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 258.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 257.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 257.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 255.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 253.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 248.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 246.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 245.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 245.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 245.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 244.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 244.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 243.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 242.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 241.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 238.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 236.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 229.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 222.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 220.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 212.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 211.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 211.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 209.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 209.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 207.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 205.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 205.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 203.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 202.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 199.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 198.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 198.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 197.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 196.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 183.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 175.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 151.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

480.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 480.6
FF:10158-103A5 76 years, female 480.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

304.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 291.6
Samples: 4

Max nTPM: 339.3
Min nTPM: 219.9
Sample A Female 339.3
Sample B Female 219.9
Sample C Male 336.6
Sample D Male 270.4
Midbrain
nTPM: 304.5
Samples: 4

Max nTPM: 397.7
Min nTPM: 263.4
Sample A Female 397.7
Sample B Female 263.4
Sample C Male 293.0
Sample D Male 264.0
Periaqueductal gray
nTPM: 236.7
Samples: 3

Max nTPM: 251.3
Min nTPM: 227.8
Sample B Female 231.0
Sample C Male 251.3
Sample D Male 227.8
Superior colliculi
nTPM: 292.4
Samples: 4

Max nTPM: 326.2
Min nTPM: 215.6
Sample A Female 312.4
Sample B Female 215.6
Sample C Male 326.2
Sample D Male 315.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

304.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 304.9
Samples: 4

Max nTPM: 322.3
Min nTPM: 297.4
Sample A Male 322.3
Sample B Male 297.4
Sample C Female 299.6
Sample D Female 300.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.8
69013750 Antisense, RP_050309_02_H09, Mouse strain C57BL/6J (56 days, male) 10.8

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