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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
85.4
nTPM
HPA:
85.4
nTPM
GTEx:
75.9
nTPM
FANTOM5:
132.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA023687
Cholangiocytes
Not detected
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
85.4
Female, age 60
Liver sample 21 nTPM: 72.9
Male, age 54
Liver sample 23 nTPM: 60.7
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 80.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 110.9
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 90.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 88.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 93.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 80.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 78.7
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 97.8
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
75.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 75.9
Samples: 226
Max nTPM: 143.4
Min nTPM: 31.8
Std nTPM: 21.9
Median nTPM: 72.0
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
143.4
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
142.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
138.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
129.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
122.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
120.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
120.3
GTEX-S32W-1926-SM-4AD63
50-59 years, female
119.0
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
118.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
118.0
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
118.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
117.5
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
117.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
115.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
115.6
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
114.9
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
113.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
110.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
108.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
107.6
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
106.8
GTEX-18A66-2026-SM-7189C
60-69 years, male
106.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
105.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
104.1
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
103.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
103.1
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
102.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
101.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
101.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
101.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
101.0
GTEX-P78B-1326-SM-3P611
40-49 years, female
101.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
100.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
100.4
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
100.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
99.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
99.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
99.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
98.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
98.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
98.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
97.8
GTEX-13113-1326-SM-5GCOI
60-69 years, female
96.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
96.5
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
95.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
95.5
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
95.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
95.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
94.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
94.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
94.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
94.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
94.0
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
93.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
93.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
93.0
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
92.8
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
92.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
92.2
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
91.4
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
90.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
88.9
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
88.9
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
88.8
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
88.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
88.2
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
88.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
87.3
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
87.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
84.9
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
84.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
84.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
84.6
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
83.9
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
83.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
83.4
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
83.4
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
83.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
83.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
83.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
82.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
82.4
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
81.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
81.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
81.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
80.9
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
80.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
80.2
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
80.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
79.8
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
79.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
79.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
78.9
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
78.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
77.9
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
77.2
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
77.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
76.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
76.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
76.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
76.1
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
76.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
75.9
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
75.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
75.3
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
75.2
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
75.2
GTEX-14JG1-1626-SM-664NH
40-49 years, male
74.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
74.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
73.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
73.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
72.4
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
72.1
GTEX-O5YV-0726-SM-EV798
60-69 years, female
72.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
71.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
71.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
71.0
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
70.8
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
70.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
70.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
70.7
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
70.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
69.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
69.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
69.0
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
68.6
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
68.4
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
68.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
68.3
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
68.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
67.7
GTEX-X261-1726-SM-4PQYT
50-59 years, male
67.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
67.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
67.4
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
67.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
66.4
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
65.7
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
65.6
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
65.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
65.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
65.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
64.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
64.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
63.9
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
63.5
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
62.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
62.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
61.6
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
61.5
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
61.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
61.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
61.1
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
61.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
60.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
60.1
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
60.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
59.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
59.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
59.5
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
59.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
59.1
GTEX-17F96-1226-SM-79OK2
70-79 years, male
58.9
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
58.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
58.6
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
58.4
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
58.0
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
57.9
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
57.6
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
57.3
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
57.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
57.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
56.9
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
56.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
56.6
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
56.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
56.3
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
56.3
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
56.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
55.9
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
55.6
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
55.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
55.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
55.4
GTEX-S33H-1626-SM-4AD68
30-39 years, male
55.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
55.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
55.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
54.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
54.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
54.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
54.3
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
54.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
53.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
53.8
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
53.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
53.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
53.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
52.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
52.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
52.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
52.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
52.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
52.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
52.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
52.1
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
51.9
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
51.6
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
51.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
51.2
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
51.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
49.9
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
49.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
48.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
47.9
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
47.2
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
47.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
46.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
46.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
45.6
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
45.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
45.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
43.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
43.6
GTEX-11GSP-0626-SM-5986T
60-69 years, female
42.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
38.8
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
36.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
31.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
