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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:72.9 nTPM
HPA Brain:316.1 nTPM
GTEx:72.9 nTPM
FANTOM5:505.9 Scaled Tags Per Million
Pig:192.8 nTPM
Mouse:80.7 nTPM
Allen mouse:9.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

316.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 249.0
2019 Male, age 18, unknown 327.5
2411 Female, age 72, unknown 300.9
1830 Male, age 51, unknown 297.0
1833 Male, age 53, unknown 281.0
1870 Female, age 42, unknown 280.9
2666 Male, age 74, left hemisphere 258.2
2828 Female, age 72, unknown 220.1
2586 Male, age 75, left hemisphere 211.2
1827 Male, age 72, unknown 188.9
2219 Male, age 76, both hemispheres 123.8
Dorsal raphe nucleus
nTPM: 184.6
2750 Male, age 76, both hemispheres 262.6
2016 Female, age 72, unknown 192.6
1828 Male, age 53, unknown 188.0
2047 Male, age 72, unknown 146.3
2298 Female, age 72, unknown 133.6
Inferior colliculus
nTPM: 172.0
1890 Male, age 53, unknown 188.4
1848 Female, age 42, unknown 177.0
2097 Female, age 72, unknown 173.2
2849 Male, age 72, unknown 149.5
Median raphe nucleus
nTPM: 159.6
2220 Male, age 76, midline 159.6
Periaquaductal grey, anterior
nTPM: 158.8
2502 Female, age 75, unknown 178.9
1947 Male, age 18, unknown 162.8
1795 Male, age 51, unknown 134.6
Periaquaductal grey, dorsal
nTPM: 142.2
2464 Female, age 72, unknown 194.8
1831 Male, age 72, unknown 151.4
2850 Male, age 76, both hemispheres 121.5
1840 Male, age 53, unknown 101.1
Periaquaductal grey, lateral
nTPM: 157.2
2272 Male, age 74, both hemispheres 174.6
2053 Male, age 18, unknown 160.1
2140 Male, age 76, both hemispheres 136.9
Pretectal area
nTPM: 185.0
1815 Male, age 53, unknown 238.5
2007 Male, age 72, unknown 214.8
1817 Female, age 42, unknown 206.6
2316 Male, age 76, right hemisphere 202.3
2407 Male, age 75, both hemispheres 202.3
2273 Male, age 74, both hemispheres 177.0
2667 Female, age 75, unknown 171.9
1944 Female, age 72, unknown 161.8
2825 Male, age 18, unknown 161.8
1816 Male, age 51, unknown 155.9
2224 Female, age 72, unknown 141.5
Red nucleus
nTPM: 316.1
1904 Male, age 53, unknown 372.9
1865 Male, age 51, unknown 366.4
1821 Female, age 72, unknown 364.2
2785 Male, age 18, unknown 341.7
2227 Male, age 72, unknown 329.7
2769 Male, age 72, unknown 327.1
2823 Male, age 76, right hemisphere 312.2
2503 Female, age 72, unknown 309.1
2588 Male, age 74, left hemisphere 300.0
1954 Female, age 42, unknown 295.4
2584 Male, age 75, left hemisphere 255.8
2725 Female, age 75, unknown 218.8
Substantia nigra
nTPM: 207.1
2583 Male, age 75, right hemisphere 263.3
2409 Female, age 72, unknown 253.9
2590 Female, age 75, unknown 234.9
1889 Female, age 72, unknown 226.4
1851 Male, age 51, unknown 221.7
2241 Male, age 72, unknown 200.4
2665 Male, age 74, both hemispheres 176.9
2699 Male, age 18, unknown 169.6
1941 Male, age 53, unknown 167.6
1916 Female, age 42, unknown 156.6
Superior colliculus
nTPM: 214.6
1913 Female, age 42, unknown 305.4
1995 Male, age 72, unknown 268.3
2587 Male, age 74, left hemisphere 257.0
2668 Female, age 75, unknown 243.5
1839 Male, age 51, unknown 203.3
1895 Male, age 76, right hemisphere 194.4
1796 Male, age 53, unknown 182.5
2261 Male, age 18, unknown 180.8
2087 Female, age 72, unknown 167.1
2664 Male, age 75, both hemispheres 143.7
Ventral tegmental area
nTPM: 215.2
2223 Female, age 72, unknown 295.4
2410 Female, age 72, unknown 269.7
2021 Male, age 53, unknown 191.1
1942 Male, age 51, unknown 188.7
2218 Male, age 76, both hemispheres 173.3
1915 Female, age 42, unknown 173.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 72.9
Samples: 139

Max nTPM: 223.5
Min nTPM: 28.6
Std nTPM: 31.9
Median nTPM: 66.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 223.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 199.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 180.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 172.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 151.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 137.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 135.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 131.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 130.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 125.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 125.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 121.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 117.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 106.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 102.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 101.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 99.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 97.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 96.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 95.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 95.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 94.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 94.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 92.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 92.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 91.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 90.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 90.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 89.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 89.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 88.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 88.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 87.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 87.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 87.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 85.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 83.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 83.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 83.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 83.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 82.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 82.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 81.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 81.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 80.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 79.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 77.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 77.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 76.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 75.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 74.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 72.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 72.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 72.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 72.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 71.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 71.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 71.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 71.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 70.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 70.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 70.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 69.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 67.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 67.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 67.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 67.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 67.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 66.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 66.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 65.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 65.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 64.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 64.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 63.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 63.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 63.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 63.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 62.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 61.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 61.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 61.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 61.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 60.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 60.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 59.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 59.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 59.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 58.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 58.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 58.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 57.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 57.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 56.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 55.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 55.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 54.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 54.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 53.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 52.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 51.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 51.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 51.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 51.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 51.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 50.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 50.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 50.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 49.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 48.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 48.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 48.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 47.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 47.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 46.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 46.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 45.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 45.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 45.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 44.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 44.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 43.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 43.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 43.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 43.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 41.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 41.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 40.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 39.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 39.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 38.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 37.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 36.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 35.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 34.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 34.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 33.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 28.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

505.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 505.9
FF:10158-103A5 76 years, female 505.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

192.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 149.3
Samples: 4

Max nTPM: 204.8
Min nTPM: 109.2
Sample A Female 148.9
Sample B Female 109.2
Sample C Male 134.3
Sample D Male 204.8
Midbrain
nTPM: 192.8
Samples: 4

Max nTPM: 249.1
Min nTPM: 143.5
Sample A Female 227.1
Sample B Female 143.5
Sample C Male 249.1
Sample D Male 151.6
Periaqueductal gray
nTPM: 114.2
Samples: 3

Max nTPM: 131.4
Min nTPM: 99.0
Sample B Female 131.4
Sample C Male 99.0
Sample D Male 112.1
Superior colliculi
nTPM: 165.0
Samples: 4

Max nTPM: 205.0
Min nTPM: 121.2
Sample A Female 153.3
Sample B Female 121.2
Sample C Male 205.0
Sample D Male 180.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

80.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 80.7
Samples: 4

Max nTPM: 91.7
Min nTPM: 67.1
Sample A Male 67.1
Sample B Male 81.4
Sample C Female 91.7
Sample D Female 82.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.1
69288327 Antisense, RP_050331_04_E09, Mouse strain C57BL/6J (56 days, male) 9.1

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