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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:36.9 nTPM
HPA Brain:138.5 nTPM
GTEx:36.9 nTPM
FANTOM5:97.3 Scaled Tags Per Million
Pig:126.3 nTPM
Mouse:117.4 nTPM
Allen mouse:14.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

138.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 118.1
2411 Female, age 72, unknown 138.0
2666 Male, age 74, left hemisphere 128.2
1833 Male, age 53, unknown 121.4
1827 Male, age 72, unknown 118.8
2019 Male, age 18, unknown 118.8
1870 Female, age 42, unknown 118.1
2586 Male, age 75, left hemisphere 114.4
1830 Male, age 51, unknown 113.0
2219 Male, age 76, both hemispheres 105.6
2828 Female, age 72, unknown 104.3
Dorsal raphe nucleus
nTPM: 123.2
2298 Female, age 72, unknown 138.8
2047 Male, age 72, unknown 128.0
2750 Male, age 76, both hemispheres 126.4
1828 Male, age 53, unknown 116.5
2016 Female, age 72, unknown 106.1
Inferior colliculus
nTPM: 115.1
2097 Female, age 72, unknown 127.3
1848 Female, age 42, unknown 117.9
2849 Male, age 72, unknown 108.4
1890 Male, age 53, unknown 106.6
Median raphe nucleus
nTPM: 132.2
2220 Male, age 76, midline 132.2
Periaquaductal grey, anterior
nTPM: 130.5
2502 Female, age 75, unknown 143.7
1947 Male, age 18, unknown 136.4
1795 Male, age 51, unknown 111.5
Periaquaductal grey, dorsal
nTPM: 108.3
1840 Male, age 53, unknown 119.4
2464 Female, age 72, unknown 110.0
2850 Male, age 76, both hemispheres 106.2
1831 Male, age 72, unknown 97.7
Periaquaductal grey, lateral
nTPM: 104.4
2053 Male, age 18, unknown 110.6
2140 Male, age 76, both hemispheres 107.7
2272 Male, age 74, both hemispheres 95.0
Pretectal area
nTPM: 119.2
2007 Male, age 72, unknown 141.7
1816 Male, age 51, unknown 133.5
1817 Female, age 42, unknown 131.8
1815 Male, age 53, unknown 128.5
2224 Female, age 72, unknown 127.1
1944 Female, age 72, unknown 126.7
2667 Female, age 75, unknown 110.9
2825 Male, age 18, unknown 110.0
2316 Male, age 76, right hemisphere 102.3
2407 Male, age 75, both hemispheres 100.2
2273 Male, age 74, both hemispheres 98.5
Red nucleus
nTPM: 115.7
1821 Female, age 72, unknown 134.6
2503 Female, age 72, unknown 123.3
1865 Male, age 51, unknown 118.4
1904 Male, age 53, unknown 116.2
2785 Male, age 18, unknown 116.2
1954 Female, age 42, unknown 116.1
2588 Male, age 74, left hemisphere 114.4
2725 Female, age 75, unknown 114.0
2769 Male, age 72, unknown 113.1
2227 Male, age 72, unknown 111.3
2584 Male, age 75, left hemisphere 110.6
2823 Male, age 76, right hemisphere 100.4
Substantia nigra
nTPM: 138.5
1916 Female, age 42, unknown 174.4
2241 Male, age 72, unknown 159.9
1851 Male, age 51, unknown 150.7
1941 Male, age 53, unknown 147.2
1889 Female, age 72, unknown 144.5
2409 Female, age 72, unknown 138.2
2699 Male, age 18, unknown 124.5
2665 Male, age 74, both hemispheres 122.7
2583 Male, age 75, right hemisphere 112.8
2590 Female, age 75, unknown 109.7
Superior colliculus
nTPM: 115.5
2668 Female, age 75, unknown 139.8
2587 Male, age 74, left hemisphere 137.0
2261 Male, age 18, unknown 119.8
2087 Female, age 72, unknown 119.5
1839 Male, age 51, unknown 116.8
1796 Male, age 53, unknown 115.4
1895 Male, age 76, right hemisphere 109.9
1913 Female, age 42, unknown 103.8
2664 Male, age 75, both hemispheres 96.9
1995 Male, age 72, unknown 96.5
Ventral tegmental area
nTPM: 129.2
2410 Female, age 72, unknown 155.8
1915 Female, age 42, unknown 135.0
2218 Male, age 76, both hemispheres 130.5
2223 Female, age 72, unknown 125.8
1942 Male, age 51, unknown 120.1
2021 Male, age 53, unknown 108.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

36.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 36.9
Samples: 139

Max nTPM: 75.8
Min nTPM: 22.1
Std nTPM: 10.3
Median nTPM: 34.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 75.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 69.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 69.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 67.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 60.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 57.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 57.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 55.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 54.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 54.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 53.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 53.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 52.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 51.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 51.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 50.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 49.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 49.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 48.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 47.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 47.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 47.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 47.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 46.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 46.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 46.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 46.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 45.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 44.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 44.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 43.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 43.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 43.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 42.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 41.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 41.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 41.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 41.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 41.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 40.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 40.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 40.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 40.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 40.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 40.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 39.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 39.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 39.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 39.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 38.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 38.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 37.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 37.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 37.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 37.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 36.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 36.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 36.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 36.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 35.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 35.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 35.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 35.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 35.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 35.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 35.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 35.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 34.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 34.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 34.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 34.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 34.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 34.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 33.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 33.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 33.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 33.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 32.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 32.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 32.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 32.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 32.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 32.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 32.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 31.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 31.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 31.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 31.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 31.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 30.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 30.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 30.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 30.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 30.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 30.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 30.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 30.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 30.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 29.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 29.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 29.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 29.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 29.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 29.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 29.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 28.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 28.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 28.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 28.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 28.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 28.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 28.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 28.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 28.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 27.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 27.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 27.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 27.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 27.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 27.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 27.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 27.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 26.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 26.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 26.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 26.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 26.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 26.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 26.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 25.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 25.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 25.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 25.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 24.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 24.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 24.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 24.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 23.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 22.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

97.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 97.3
FF:10158-103A5 76 years, female 97.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

126.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 110.1
Samples: 4

Max nTPM: 144.8
Min nTPM: 81.8
Sample A Female 144.8
Sample B Female 91.6
Sample C Male 122.2
Sample D Male 81.8
Midbrain
nTPM: 126.3
Samples: 4

Max nTPM: 146.2
Min nTPM: 109.0
Sample A Female 128.2
Sample B Female 109.0
Sample C Male 146.2
Sample D Male 121.6
Periaqueductal gray
nTPM: 94.0
Samples: 3

Max nTPM: 102.3
Min nTPM: 86.0
Sample B Female 93.7
Sample C Male 102.3
Sample D Male 86.0
Superior colliculi
nTPM: 117.8
Samples: 4

Max nTPM: 139.0
Min nTPM: 89.3
Sample A Female 130.1
Sample B Female 89.3
Sample C Male 139.0
Sample D Male 112.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

117.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 117.4
Samples: 4

Max nTPM: 125.8
Min nTPM: 110.8
Sample A Male 110.8
Sample B Male 117.2
Sample C Female 125.8
Sample D Female 115.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.4
67814217 Antisense, RP_040920_01_G05, Mouse strain C57BL/6J (56 days, male) 14.4

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