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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:103.1 nTPM
HPA Brain:89.5 nTPM
GTEx:103.1 nTPM
FANTOM5:310.1 Scaled Tags Per Million
Pig:192.9 nTPM
Mouse:141.2 nTPM
Allen mouse:4.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

89.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 74.7
1870 Female, age 42, unknown 93.9
2828 Female, age 72, unknown 87.7
2411 Female, age 72, unknown 85.2
1833 Male, age 53, unknown 82.4
1830 Male, age 51, unknown 79.0
2019 Male, age 18, unknown 73.7
1827 Male, age 72, unknown 70.2
2219 Male, age 76, both hemispheres 61.9
2586 Male, age 75, left hemisphere 57.8
2666 Male, age 74, left hemisphere 54.7
Dorsal raphe nucleus
nTPM: 89.5
2016 Female, age 72, unknown 101.2
2298 Female, age 72, unknown 97.6
2750 Male, age 76, both hemispheres 96.2
1828 Male, age 53, unknown 83.8
2047 Male, age 72, unknown 68.8
Inferior colliculus
nTPM: 69.7
2097 Female, age 72, unknown 74.5
1848 Female, age 42, unknown 72.5
1890 Male, age 53, unknown 66.3
2849 Male, age 72, unknown 65.8
Median raphe nucleus
nTPM: 66.1
2220 Male, age 76, midline 66.1
Periaquaductal grey, anterior
nTPM: 70.9
1947 Male, age 18, unknown 74.9
1795 Male, age 51, unknown 71.1
2502 Female, age 75, unknown 66.7
Periaquaductal grey, dorsal
nTPM: 84.6
2850 Male, age 76, both hemispheres 108.0
2464 Female, age 72, unknown 79.2
1840 Male, age 53, unknown 77.7
1831 Male, age 72, unknown 73.5
Periaquaductal grey, lateral
nTPM: 86.0
2140 Male, age 76, both hemispheres 89.9
2053 Male, age 18, unknown 87.4
2272 Male, age 74, both hemispheres 80.7
Pretectal area
nTPM: 77.9
2273 Male, age 74, both hemispheres 105.5
2316 Male, age 76, right hemisphere 98.5
2224 Female, age 72, unknown 94.0
2667 Female, age 75, unknown 91.2
1815 Male, age 53, unknown 77.9
2825 Male, age 18, unknown 77.0
1817 Female, age 42, unknown 72.4
2407 Male, age 75, both hemispheres 64.7
1944 Female, age 72, unknown 62.4
2007 Male, age 72, unknown 57.6
1816 Male, age 51, unknown 55.8
Red nucleus
nTPM: 88.3
1904 Male, age 53, unknown 107.2
1821 Female, age 72, unknown 103.6
1865 Male, age 51, unknown 102.8
1954 Female, age 42, unknown 102.8
2823 Male, age 76, right hemisphere 100.8
2769 Male, age 72, unknown 97.8
2227 Male, age 72, unknown 96.6
2503 Female, age 72, unknown 90.4
2725 Female, age 75, unknown 87.8
2785 Male, age 18, unknown 76.2
2588 Male, age 74, left hemisphere 53.7
2584 Male, age 75, left hemisphere 40.3
Substantia nigra
nTPM: 69.0
2699 Male, age 18, unknown 90.6
1851 Male, age 51, unknown 80.1
2409 Female, age 72, unknown 79.7
1889 Female, age 72, unknown 72.1
2241 Male, age 72, unknown 68.8
1916 Female, age 42, unknown 67.4
2590 Female, age 75, unknown 66.3
1941 Male, age 53, unknown 60.6
2583 Male, age 75, right hemisphere 59.1
2665 Male, age 74, both hemispheres 45.0
Superior colliculus
nTPM: 80.7
1995 Male, age 72, unknown 128.0
1913 Female, age 42, unknown 106.0
1895 Male, age 76, right hemisphere 84.9
2587 Male, age 74, left hemisphere 78.4
1796 Male, age 53, unknown 75.0
1839 Male, age 51, unknown 74.4
2668 Female, age 75, unknown 69.2
2087 Female, age 72, unknown 67.9
2664 Male, age 75, both hemispheres 62.9
2261 Male, age 18, unknown 60.5
Ventral tegmental area
nTPM: 74.8
2410 Female, age 72, unknown 89.0
1915 Female, age 42, unknown 73.5
2021 Male, age 53, unknown 72.8
2223 Female, age 72, unknown 72.3
2218 Male, age 76, both hemispheres 71.3
1942 Male, age 51, unknown 70.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

103.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 103.1
Samples: 139

Max nTPM: 198.5
Min nTPM: 27.5
Std nTPM: 33.8
Median nTPM: 98.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 198.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 180.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 175.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 169.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 168.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 167.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 165.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 164.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 160.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 160.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 160.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 160.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 159.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 159.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 156.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 155.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 155.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 153.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 143.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 143.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 141.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 140.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 139.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 137.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 134.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 132.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 131.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 130.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 129.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 126.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 126.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 125.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 124.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 123.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 122.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 122.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 122.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 120.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 120.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 119.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 119.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 119.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 118.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 118.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 117.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 117.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 117.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 116.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 115.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 114.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 113.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 113.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 113.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 112.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 111.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 111.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 111.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 111.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 106.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 105.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 105.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 103.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 102.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 100.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 100.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 100.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 100.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 98.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 98.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 98.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 98.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 98.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 96.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 96.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 96.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 94.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 93.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 92.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 91.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 91.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 90.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 89.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 88.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 88.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 88.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 87.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 87.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 86.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 85.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 85.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 85.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 85.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 84.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 84.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 84.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 83.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 83.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 82.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 82.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 80.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 80.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 80.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 79.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 79.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 79.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 78.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 78.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 77.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 76.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 76.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 75.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 75.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 73.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 72.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 70.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 69.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 69.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 69.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 68.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 68.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 68.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 65.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 65.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 64.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 63.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 63.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 61.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 57.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 57.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 56.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 56.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 55.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 53.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 52.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 49.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 47.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 45.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 41.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 27.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

310.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 310.1
FF:10158-103A5 76 years, female 310.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

192.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 179.3
Samples: 4

Max nTPM: 214.5
Min nTPM: 165.8
Sample A Female 214.5
Sample B Female 165.8
Sample C Male 170.2
Sample D Male 166.6
Midbrain
nTPM: 192.9
Samples: 4

Max nTPM: 329.2
Min nTPM: 105.2
Sample A Female 329.2
Sample B Female 186.8
Sample C Male 150.4
Sample D Male 105.2
Periaqueductal gray
nTPM: 184.9
Samples: 3

Max nTPM: 216.1
Min nTPM: 164.9
Sample B Female 216.1
Sample C Male 164.9
Sample D Male 173.6
Superior colliculi
nTPM: 136.1
Samples: 4

Max nTPM: 158.9
Min nTPM: 90.3
Sample A Female 158.9
Sample B Female 90.3
Sample C Male 150.2
Sample D Male 145.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

141.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 141.3
Samples: 4

Max nTPM: 150.4
Min nTPM: 130.1
Sample A Male 138.0
Sample B Male 130.1
Sample C Female 146.5
Sample D Female 150.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.9
76081936 Antisense, RP_060626_01_B01, Mouse strain C57BL/6J (56 days, male) 4.9

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