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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:97.0 nTPM
HPA Brain:91.5 nTPM
GTEx:97.0 nTPM
FANTOM5:84.0 Scaled Tags Per Million
Pig:72.3 nTPM
Mouse:123.5 nTPM
Allen mouse:15.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

91.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 77.5
2411 Female, age 72, unknown 89.4
2019 Male, age 18, unknown 84.6
1870 Female, age 42, unknown 83.5
2219 Male, age 76, both hemispheres 83.0
1827 Male, age 72, unknown 81.9
1833 Male, age 53, unknown 75.9
2828 Female, age 72, unknown 71.8
1830 Male, age 51, unknown 70.8
2666 Male, age 74, left hemisphere 68.3
2586 Male, age 75, left hemisphere 66.2
Dorsal raphe nucleus
nTPM: 86.2
2298 Female, age 72, unknown 107.7
2047 Male, age 72, unknown 87.4
2750 Male, age 76, both hemispheres 83.5
1828 Male, age 53, unknown 77.7
2016 Female, age 72, unknown 74.5
Inferior colliculus
nTPM: 76.9
1848 Female, age 42, unknown 79.3
2097 Female, age 72, unknown 78.7
1890 Male, age 53, unknown 75.3
2849 Male, age 72, unknown 74.2
Median raphe nucleus
nTPM: 82.9
2220 Male, age 76, midline 82.9
Periaquaductal grey, anterior
nTPM: 76.1
2502 Female, age 75, unknown 79.1
1795 Male, age 51, unknown 75.0
1947 Male, age 18, unknown 74.2
Periaquaductal grey, dorsal
nTPM: 75.5
1840 Male, age 53, unknown 84.7
2850 Male, age 76, both hemispheres 77.1
1831 Male, age 72, unknown 70.1
2464 Female, age 72, unknown 70.1
Periaquaductal grey, lateral
nTPM: 75.8
2272 Male, age 74, both hemispheres 83.7
2053 Male, age 18, unknown 73.4
2140 Male, age 76, both hemispheres 70.3
Pretectal area
nTPM: 82.0
2007 Male, age 72, unknown 93.3
1817 Female, age 42, unknown 91.7
1816 Male, age 51, unknown 91.6
2273 Male, age 74, both hemispheres 89.2
1944 Female, age 72, unknown 85.6
2224 Female, age 72, unknown 84.6
1815 Male, age 53, unknown 83.2
2667 Female, age 75, unknown 79.9
2825 Male, age 18, unknown 73.6
2316 Male, age 76, right hemisphere 66.2
2407 Male, age 75, both hemispheres 63.2
Red nucleus
nTPM: 77.8
1821 Female, age 72, unknown 98.5
2725 Female, age 75, unknown 89.2
2785 Male, age 18, unknown 81.6
2503 Female, age 72, unknown 80.1
1954 Female, age 42, unknown 78.4
1904 Male, age 53, unknown 77.9
2769 Male, age 72, unknown 75.2
2588 Male, age 74, left hemisphere 74.8
1865 Male, age 51, unknown 74.4
2227 Male, age 72, unknown 73.2
2823 Male, age 76, right hemisphere 72.3
2584 Male, age 75, left hemisphere 58.7
Substantia nigra
nTPM: 91.5
1916 Female, age 42, unknown 119.1
1851 Male, age 51, unknown 101.3
1889 Female, age 72, unknown 96.4
2241 Male, age 72, unknown 95.9
2409 Female, age 72, unknown 93.7
1941 Male, age 53, unknown 93.5
2699 Male, age 18, unknown 83.5
2665 Male, age 74, both hemispheres 83.0
2590 Female, age 75, unknown 79.3
2583 Male, age 75, right hemisphere 69.0
Superior colliculus
nTPM: 74.1
2587 Male, age 74, left hemisphere 86.8
1796 Male, age 53, unknown 84.1
2261 Male, age 18, unknown 80.4
1895 Male, age 76, right hemisphere 79.4
1839 Male, age 51, unknown 76.6
2087 Female, age 72, unknown 74.0
2668 Female, age 75, unknown 71.1
1913 Female, age 42, unknown 70.2
1995 Male, age 72, unknown 67.2
2664 Male, age 75, both hemispheres 51.0
Ventral tegmental area
nTPM: 83.5
2410 Female, age 72, unknown 98.8
1915 Female, age 42, unknown 97.6
2218 Male, age 76, both hemispheres 86.3
2223 Female, age 72, unknown 77.3
1942 Male, age 51, unknown 72.2
2021 Male, age 53, unknown 68.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

97.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 97.0
Samples: 139

Max nTPM: 150.8
Min nTPM: 63.4
Std nTPM: 18.6
Median nTPM: 93.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 150.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 150.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 149.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 148.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 146.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 142.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 142.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 137.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 137.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 135.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 131.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 130.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 129.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 123.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 122.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 118.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 118.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 117.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 116.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 116.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 115.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 115.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 113.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 111.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 108.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 107.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 107.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 107.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 107.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 107.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 107.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 107.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 107.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 106.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 106.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 105.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 104.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 104.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 104.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 104.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 103.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 103.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 102.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 101.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 101.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 101.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 100.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 100.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 100.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 99.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 99.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 99.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 97.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 97.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 96.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 96.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 96.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 96.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 96.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 95.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 95.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 95.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 94.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 94.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 94.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 93.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 93.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 93.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 93.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 93.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 93.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 92.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 92.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 92.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 91.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 91.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 91.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 91.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 90.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 90.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 89.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 89.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 89.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 89.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 88.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 88.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 87.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 87.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 87.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 86.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 86.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 86.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 86.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 86.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 86.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 86.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 86.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 85.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 84.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 84.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 84.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 84.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 84.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 84.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 84.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 83.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 83.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 83.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 83.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 82.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 82.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 82.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 81.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 81.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 81.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 81.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 81.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 81.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 81.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 79.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 79.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 79.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 79.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 79.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 78.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 78.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 77.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 76.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 76.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 76.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 76.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 75.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 74.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 73.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 72.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 72.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 72.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 63.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 63.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

84.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 84.0
FF:10158-103A5 76 years, female 84.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 70.0
Samples: 4

Max nTPM: 89.2
Min nTPM: 58.0
Sample A Female 89.2
Sample B Female 58.7
Sample C Male 74.0
Sample D Male 58.0
Midbrain
nTPM: 72.3
Samples: 4

Max nTPM: 91.6
Min nTPM: 62.2
Sample A Female 91.6
Sample B Female 66.2
Sample C Male 69.3
Sample D Male 62.2
Periaqueductal gray
nTPM: 59.4
Samples: 3

Max nTPM: 68.2
Min nTPM: 53.1
Sample B Female 56.8
Sample C Male 68.2
Sample D Male 53.1
Superior colliculi
nTPM: 71.3
Samples: 4

Max nTPM: 78.5
Min nTPM: 65.9
Sample A Female 78.5
Sample B Female 69.3
Sample C Male 71.6
Sample D Male 65.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

123.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 123.5
Samples: 4

Max nTPM: 148.1
Min nTPM: 105.7
Sample A Male 148.1
Sample B Male 127.0
Sample C Female 113.1
Sample D Female 105.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.7
81600108 Antisense, RP_080205_02_D01, Mouse strain C57BL/6J (56 days, male) 17.3
413791 Antisense, RP_040809_01_E01, Mouse strain C57BL/6J (56 days, male) 14.2

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