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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:11.7 nTPM
HPA Brain:85.5 nTPM
GTEx:11.7 nTPM
FANTOM5:2.1 Scaled Tags Per Million
Pig:85.4 nTPM
Mouse:54.4 nTPM
Allen mouse:14.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

85.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 45.7
2666 Male, age 74, left hemisphere 74.2
2019 Male, age 18, unknown 71.6
1827 Male, age 72, unknown 57.7
2828 Female, age 72, unknown 57.3
2586 Male, age 75, left hemisphere 46.6
2219 Male, age 76, both hemispheres 46.1
1870 Female, age 42, unknown 28.0
2411 Female, age 72, unknown 27.1
1833 Male, age 53, unknown 25.0
1830 Male, age 51, unknown 23.8
Dorsal raphe nucleus
nTPM: 22.3
2298 Female, age 72, unknown 29.8
2750 Male, age 76, both hemispheres 22.8
1828 Male, age 53, unknown 21.3
2047 Male, age 72, unknown 19.6
2016 Female, age 72, unknown 18.0
Inferior colliculus
nTPM: 33.9
2097 Female, age 72, unknown 48.5
1890 Male, age 53, unknown 34.4
1848 Female, age 42, unknown 31.6
2849 Male, age 72, unknown 21.1
Median raphe nucleus
nTPM: 30.3
2220 Male, age 76, midline 30.3
Periaquaductal grey, anterior
nTPM: 46.1
1795 Male, age 51, unknown 70.2
2502 Female, age 75, unknown 35.9
1947 Male, age 18, unknown 32.4
Periaquaductal grey, dorsal
nTPM: 37.1
1831 Male, age 72, unknown 68.5
1840 Male, age 53, unknown 28.2
2464 Female, age 72, unknown 27.3
2850 Male, age 76, both hemispheres 24.5
Periaquaductal grey, lateral
nTPM: 26.1
2053 Male, age 18, unknown 34.9
2140 Male, age 76, both hemispheres 25.4
2272 Male, age 74, both hemispheres 17.8
Pretectal area
nTPM: 85.5
1816 Male, age 51, unknown 173.6
1944 Female, age 72, unknown 147.8
1817 Female, age 42, unknown 137.8
2007 Male, age 72, unknown 119.1
1815 Male, age 53, unknown 117.3
2667 Female, age 75, unknown 81.0
2224 Female, age 72, unknown 38.3
2273 Male, age 74, both hemispheres 35.8
2407 Male, age 75, both hemispheres 32.4
2316 Male, age 76, right hemisphere 31.0
2825 Male, age 18, unknown 26.9
Red nucleus
nTPM: 28.4
2785 Male, age 18, unknown 73.2
2584 Male, age 75, left hemisphere 39.0
1954 Female, age 42, unknown 29.3
2503 Female, age 72, unknown 26.3
2823 Male, age 76, right hemisphere 26.3
1904 Male, age 53, unknown 26.2
1821 Female, age 72, unknown 25.6
1865 Male, age 51, unknown 23.3
2227 Male, age 72, unknown 19.4
2588 Male, age 74, left hemisphere 19.4
2769 Male, age 72, unknown 19.4
2725 Female, age 75, unknown 13.2
Substantia nigra
nTPM: 43.6
1889 Female, age 72, unknown 101.0
2665 Male, age 74, both hemispheres 53.7
1916 Female, age 42, unknown 51.8
1941 Male, age 53, unknown 49.0
2583 Male, age 75, right hemisphere 41.0
2409 Female, age 72, unknown 38.0
1851 Male, age 51, unknown 35.7
2241 Male, age 72, unknown 27.0
2590 Female, age 75, unknown 22.8
2699 Male, age 18, unknown 16.1
Superior colliculus
nTPM: 71.9
2668 Female, age 75, unknown 196.4
2087 Female, age 72, unknown 115.8
2261 Male, age 18, unknown 72.7
1796 Male, age 53, unknown 68.0
1913 Female, age 42, unknown 63.6
2664 Male, age 75, both hemispheres 56.1
1995 Male, age 72, unknown 53.5
1895 Male, age 76, right hemisphere 38.0
1839 Male, age 51, unknown 31.3
2587 Male, age 74, left hemisphere 23.3
Ventral tegmental area
nTPM: 34.1
2410 Female, age 72, unknown 42.1
2218 Male, age 76, both hemispheres 39.4
1915 Female, age 42, unknown 34.4
1942 Male, age 51, unknown 32.8
2223 Female, age 72, unknown 29.5
2021 Male, age 53, unknown 26.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

11.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 11.7
Samples: 139

Max nTPM: 63.6
Min nTPM: 0.4
Std nTPM: 9.2
Median nTPM: 9.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 63.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 45.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 36.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 34.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 32.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 31.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 31.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 28.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 23.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 23.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 22.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 21.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 21.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 21.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 21.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 20.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 20.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 20.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 20.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 20.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 19.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 19.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 19.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 18.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 18.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 18.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 17.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 17.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 17.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 17.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 17.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 17.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 16.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 16.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 16.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 16.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 15.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 15.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 15.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 15.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 15.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 15.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 15.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 14.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 14.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 14.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 14.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 14.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 14.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 13.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 13.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 13.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 12.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 12.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 12.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 11.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 11.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 11.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 11.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 11.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 11.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 10.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 10.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 10.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 10.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 10.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 10.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 10.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 10.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 9.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 9.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 9.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 9.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 9.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 9.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 9.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 9.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 8.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 8.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 8.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 8.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 8.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 8.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 8.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 7.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 7.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 7.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 7.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 7.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 7.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 6.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 6.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 6.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 5.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 5.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 5.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 5.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 5.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 5.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 5.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 5.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 5.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 5.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 5.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 5.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 5.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 4.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 4.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 4.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 4.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 4.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 3.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 3.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 3.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 3.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 3.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 3.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 3.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 3.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 3.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 3.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 2.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 2.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 2.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 0.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 0.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 0.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 0.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 0.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

2.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2.1
FF:10158-103A5 76 years, female 2.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

85.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 20.7
Samples: 4

Max nTPM: 30.6
Min nTPM: 8.3
Sample A Female 28.7
Sample B Female 15.3
Sample C Male 30.6
Sample D Male 8.3
Midbrain
nTPM: 83.4
Samples: 4

Max nTPM: 259.5
Min nTPM: 11.2
Sample A Female 11.2
Sample B Female 18.7
Sample C Male 259.5
Sample D Male 44.0
Periaqueductal gray
nTPM: 20.1
Samples: 3

Max nTPM: 24.8
Min nTPM: 16.6
Sample B Female 18.9
Sample C Male 24.8
Sample D Male 16.6
Superior colliculi
nTPM: 85.4
Samples: 4

Max nTPM: 184.7
Min nTPM: 41.7
Sample A Female 41.7
Sample B Female 46.1
Sample C Male 184.7
Sample D Male 68.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

54.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 54.4
Samples: 4

Max nTPM: 59.7
Min nTPM: 50.3
Sample A Male 50.3
Sample B Male 53.1
Sample C Female 59.7
Sample D Female 54.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.0
71247614 Antisense, RP_050331_02_H08, Mouse strain C57BL/6J (56 days, male) 14.0
69257594 Antisense, RP_050331_02_H08, Mouse strain C57BL/6J (56 days, male) 12.1

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