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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:135.4 nTPM
HPA Brain:282.9 nTPM
GTEx:135.4 nTPM
FANTOM5:632.3 Scaled Tags Per Million
Pig:362.8 nTPM
Mouse:329.9 nTPM
Allen mouse:12.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

282.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 204.7
2411 Female, age 72, unknown 316.9
1830 Male, age 51, unknown 274.5
1833 Male, age 53, unknown 262.8
2019 Male, age 18, unknown 256.9
1870 Female, age 42, unknown 254.6
2828 Female, age 72, unknown 186.6
2219 Male, age 76, both hemispheres 163.1
1827 Male, age 72, unknown 143.7
2666 Male, age 74, left hemisphere 124.0
2586 Male, age 75, left hemisphere 63.8
Dorsal raphe nucleus
nTPM: 165.8
2750 Male, age 76, both hemispheres 351.0
2016 Female, age 72, unknown 158.1
1828 Male, age 53, unknown 139.8
2298 Female, age 72, unknown 101.5
2047 Male, age 72, unknown 78.6
Inferior colliculus
nTPM: 128.9
1890 Male, age 53, unknown 136.4
1848 Female, age 42, unknown 135.2
2097 Female, age 72, unknown 125.0
2849 Male, age 72, unknown 119.2
Median raphe nucleus
nTPM: 151.9
2220 Male, age 76, midline 151.9
Periaquaductal grey, anterior
nTPM: 130.9
1947 Male, age 18, unknown 183.9
2502 Female, age 75, unknown 126.6
1795 Male, age 51, unknown 82.3
Periaquaductal grey, dorsal
nTPM: 93.4
2464 Female, age 72, unknown 161.1
1831 Male, age 72, unknown 90.7
2850 Male, age 76, both hemispheres 70.5
1840 Male, age 53, unknown 51.4
Periaquaductal grey, lateral
nTPM: 109.5
2272 Male, age 74, both hemispheres 163.4
2053 Male, age 18, unknown 100.8
2140 Male, age 76, both hemispheres 64.4
Pretectal area
nTPM: 127.5
2316 Male, age 76, right hemisphere 197.5
1815 Male, age 53, unknown 188.6
2273 Male, age 74, both hemispheres 151.9
1817 Female, age 42, unknown 147.5
2007 Male, age 72, unknown 141.3
2407 Male, age 75, both hemispheres 125.0
2825 Male, age 18, unknown 114.0
2224 Female, age 72, unknown 109.2
2667 Female, age 75, unknown 79.2
1944 Female, age 72, unknown 76.0
1816 Male, age 51, unknown 72.7
Red nucleus
nTPM: 282.9
1821 Female, age 72, unknown 390.3
1865 Male, age 51, unknown 382.4
1904 Male, age 53, unknown 354.6
2823 Male, age 76, right hemisphere 354.5
2227 Male, age 72, unknown 289.2
2769 Male, age 72, unknown 289.0
2503 Female, age 72, unknown 286.7
1954 Female, age 42, unknown 276.8
2785 Male, age 18, unknown 272.3
2725 Female, age 75, unknown 210.0
2588 Male, age 74, left hemisphere 173.5
2584 Male, age 75, left hemisphere 115.3
Substantia nigra
nTPM: 147.4
2409 Female, age 72, unknown 213.8
2590 Female, age 75, unknown 211.1
1851 Male, age 51, unknown 178.8
1889 Female, age 72, unknown 175.3
2241 Male, age 72, unknown 156.6
2583 Male, age 75, right hemisphere 136.8
1941 Male, age 53, unknown 120.9
2699 Male, age 18, unknown 109.4
1916 Female, age 42, unknown 103.7
2665 Male, age 74, both hemispheres 67.2
Superior colliculus
nTPM: 173.9
1913 Female, age 42, unknown 261.2
1995 Male, age 72, unknown 249.7
1895 Male, age 76, right hemisphere 249.3
2587 Male, age 74, left hemisphere 221.4
2668 Female, age 75, unknown 198.1
1839 Male, age 51, unknown 175.7
1796 Male, age 53, unknown 129.5
2261 Male, age 18, unknown 104.0
2087 Female, age 72, unknown 96.7
2664 Male, age 75, both hemispheres 53.3
Ventral tegmental area
nTPM: 182.1
2223 Female, age 72, unknown 275.5
2410 Female, age 72, unknown 252.9
2218 Male, age 76, both hemispheres 158.6
1942 Male, age 51, unknown 144.1
2021 Male, age 53, unknown 134.3
1915 Female, age 42, unknown 127.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

135.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 135.4
Samples: 139

Max nTPM: 535.4
Min nTPM: 26.0
Std nTPM: 84.0
Median nTPM: 112.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 535.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 396.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 389.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 387.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 381.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 373.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 362.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 284.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 284.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 274.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 252.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 248.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 246.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 232.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 227.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 224.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 220.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 219.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 214.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 213.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 211.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 211.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 208.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 207.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 206.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 202.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 189.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 185.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 185.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 183.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 182.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 173.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 172.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 168.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 163.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 158.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 157.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 153.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 150.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 145.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 145.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 142.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 141.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 138.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 136.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 136.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 134.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 134.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 131.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 128.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 127.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 127.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 126.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 126.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 124.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 124.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 124.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 123.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 123.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 122.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 121.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 121.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 120.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 117.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 117.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 116.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 116.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 114.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 114.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 112.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 110.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 110.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 108.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 107.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 107.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 103.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 102.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 101.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 101.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 97.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 96.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 95.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 95.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 95.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 94.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 94.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 93.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 93.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 92.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 91.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 90.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 90.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 89.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 89.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 89.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 88.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 88.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 87.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 87.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 86.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 86.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 86.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 86.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 85.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 85.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 83.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 82.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 82.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 82.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 81.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 79.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 78.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 76.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 72.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 72.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 72.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 72.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 69.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 68.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 67.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 67.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 65.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 64.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 62.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 62.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 62.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 59.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 59.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 54.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 54.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 50.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 47.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 47.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 46.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 44.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 41.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 40.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 34.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 26.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

632.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 632.3
FF:10158-103A5 76 years, female 632.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

362.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 294.3
Samples: 4

Max nTPM: 486.2
Min nTPM: 208.3
Sample A Female 258.4
Sample B Female 208.3
Sample C Male 224.2
Sample D Male 486.2
Midbrain
nTPM: 302.4
Samples: 4

Max nTPM: 612.2
Min nTPM: 145.6
Sample A Female 612.2
Sample B Female 292.8
Sample C Male 145.6
Sample D Male 158.8
Periaqueductal gray
nTPM: 190.6
Samples: 3

Max nTPM: 248.4
Min nTPM: 137.2
Sample B Female 248.4
Sample C Male 137.2
Sample D Male 186.1
Superior colliculi
nTPM: 362.8
Samples: 4

Max nTPM: 748.4
Min nTPM: 210.4
Sample A Female 227.0
Sample B Female 748.4
Sample C Male 210.4
Sample D Male 265.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

329.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 329.9
Samples: 4

Max nTPM: 352.8
Min nTPM: 309.0
Sample A Male 309.0
Sample B Male 319.2
Sample C Female 352.8
Sample D Female 338.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.3
70613967 Antisense, RP_050725_01_C07, Mouse strain C57BL/6J (56 days, male) 14.9
77413700 Antisense, RP_070205_01_E04, Mouse strain C57BL/6J (56 days, male) 12.4
532631 Antisense, RP_040810_02_G06, Mouse strain C57BL/6J (56 days, male) 9.5

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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