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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
222.4
nTPM
HPA:
222.4
nTPM
GTEx:
122.2
nTPM
FANTOM5:
400.2
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA020659
Cholangiocytes
Not detected
Hepatocytes
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
222.4
Female, age 60
Liver sample 21 nTPM: 225.4
Male, age 54
Liver sample 23 nTPM: 257.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 196.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 169
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 160.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 230.9
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 212.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 234.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 214.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 323
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
122.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 122.2
Samples: 226
Max nTPM: 381.3
Min nTPM: 13.3
Std nTPM: 69.7
Median nTPM: 108.1
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
381.3
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
321.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
308.9
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
296.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
293.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
292.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
289.8
GTEX-17HHE-0126-SM-79398
50-59 years, male
289.4
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
288.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
271.4
GTEX-QESD-2026-SM-447BI
20-29 years, male
260.8
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
253.6
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
244.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
242.6
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
241.8
GTEX-17F96-1226-SM-79OK2
70-79 years, male
241.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
236.2
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
232.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
231.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
229.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
228.6
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
228.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
225.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
224.4
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
220.2
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
208.2
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
205.3
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
203.6
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
203.5
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
202.8
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
199.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
198.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
198.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
196.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
196.3
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
190.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
189.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
189.6
GTEX-Q734-0326-SM-48U15
40-49 years, female
188.9
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
187.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
187.6
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
186.0
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
185.0
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
184.3
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
183.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
182.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
181.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
181.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
175.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
173.6
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
172.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
171.7
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
169.8
GTEX-18A66-2026-SM-7189C
60-69 years, male
168.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
168.2
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
165.9
GTEX-11ZUS-2526-SM-59872
30-39 years, male
164.8
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
164.7
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
163.8
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
160.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
160.7
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
156.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
155.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
154.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
153.1
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
152.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
150.9
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
148.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
146.2
GTEX-18A7A-1526-SM-72D69
50-59 years, female
146.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
145.9
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
145.5
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
145.5
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
145.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
145.2
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
143.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
142.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
142.1
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
141.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
140.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
134.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
134.9
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
132.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
129.7
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
129.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
129.0
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
128.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
126.6
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
126.4
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
125.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
125.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
124.7
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
123.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
123.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
123.0
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
122.2
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
122.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
121.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
121.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
119.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
117.1
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
115.6
GTEX-QEL4-1226-SM-447A4
50-59 years, male
115.5
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
114.9
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
114.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
114.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
114.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
114.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
112.6
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
112.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
110.5
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
110.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
109.0
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
107.2
GTEX-18465-1626-SM-7LG6N
50-59 years, male
106.6
GTEX-1399T-0826-SM-5IFES
60-69 years, male
105.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
104.5
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
104.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
103.9
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
103.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
103.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
102.7
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
102.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
102.3
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
102.0
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
100.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
100.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
99.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
98.0
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
97.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
95.8
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
95.3
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
93.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
92.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
92.1
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
90.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
90.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
89.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
89.5
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
88.6
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
88.1
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
87.3
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
87.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
86.1
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
85.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
85.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
84.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
81.5
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
81.0
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
81.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
80.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
80.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
79.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
79.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
78.9
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
78.8
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
77.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
77.4
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
75.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
75.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
74.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
74.0
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
73.4
GTEX-144GL-1426-SM-79OMA
50-59 years, male
73.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
72.4
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
71.8
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
71.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
71.1
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
70.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
70.2
GTEX-YECK-1926-SM-4W21H
60-69 years, male
70.1
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
69.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
69.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
67.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
66.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
65.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
65.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
65.7
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
65.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
64.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
63.5
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
63.4
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
63.2
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
62.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
62.4
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
61.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
60.9
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
59.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
59.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
58.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
57.5
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
54.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
53.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
51.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
51.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
50.9
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
46.6
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
45.3
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
45.3
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
44.6
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
44.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
43.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
41.8
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
40.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
40.0
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
39.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
39.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
38.9
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
38.5
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
38.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
38.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
37.0
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
33.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
32.9
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
31.4
GTEX-14PJO-1726-SM-68719
60-69 years, male
30.7
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
30.2
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
29.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
23.6
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
22.9
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
22.0
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
20.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
19.8
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
17.1
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
15.9
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
13.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
