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NUSAP1
HPA
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  • NUSAP1
PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

NUSAP1
Synonyms ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL
Gene descriptioni

Full gene name according to HGNC.

Nucleolar and spindle associated protein 1
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 15
Cytoband q15.1
Chromosome location (bp) 41320794 - 41381050
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

7
Ensembl ENSG00000137804 (version 109)
Entrez gene 51203
HGNC HGNC:18538
UniProt Q9BXS6 (UniProt - Evidence at protein level)
neXtProt NX_Q9BXS6
GeneCards NUSAP1
Antibodypedia NUSAP1 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them.... show less
Molecular function (UniProt)i

Keywords assigned by UniProt to proteins due to their particular molecular function.

DNA-binding
Biological process (UniProt)i

Keywords assigned by UniProt to proteins because they are involved in a particular biological process.

Cell cycle, Cell division, Mitosis
Gene summary (Entrez)i

Useful information about the gene from Entrez

NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al., 2003).[supplied by OMIM, Jun 2009]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
NUSAP1-201
ENSP00000260359
ENST00000260359
Q9BXS6
[Direct mapping] Nucleolar and spindle-associated protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000281 [mitotic cytokinesis]
GO:0003677 [DNA binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0005856 [cytoskeleton]
GO:0005874 [microtubule]
GO:0007049 [cell cycle]
GO:0007076 [mitotic chromosome condensation]
GO:0008017 [microtubule binding]
GO:0040001 [establishment of mitotic spindle localization]
GO:0045840 [positive regulation of mitotic nuclear division]
GO:0051301 [cell division]
GO:0072686 [mitotic spindle]
Show all
426 aa
47.7 kDa
No 0
NUSAP1-202
ENSP00000400746
ENST00000414849
Q9BXS6
[Direct mapping] Nucleolar and spindle-associated protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000281 [mitotic cytokinesis]
GO:0003677 [DNA binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0005856 [cytoskeleton]
GO:0005874 [microtubule]
GO:0007049 [cell cycle]
GO:0007076 [mitotic chromosome condensation]
GO:0008017 [microtubule binding]
GO:0040001 [establishment of mitotic spindle localization]
GO:0045840 [positive regulation of mitotic nuclear division]
GO:0051301 [cell division]
GO:0072686 [mitotic spindle]
Show all
440 aa
49.3 kDa
No 0
NUSAP1-203
ENSP00000401014
ENST00000450592
Q9BXS6
[Direct mapping] Nucleolar and spindle-associated protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000281 [mitotic cytokinesis]
GO:0003677 [DNA binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0005856 [cytoskeleton]
GO:0005874 [microtubule]
GO:0007049 [cell cycle]
GO:0007076 [mitotic chromosome condensation]
GO:0008017 [microtubule binding]
GO:0040001 [establishment of mitotic spindle localization]
GO:0045840 [positive regulation of mitotic nuclear division]
GO:0051301 [cell division]
GO:0072686 [mitotic spindle]
Show all
378 aa
42.4 kDa
No 0
NUSAP1-208
ENSP00000453403
ENST00000559596
Q9BXS6
[Direct mapping] Nucleolar and spindle-associated protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000281 [mitotic cytokinesis]
GO:0003677 [DNA binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0005856 [cytoskeleton]
GO:0005874 [microtubule]
GO:0007049 [cell cycle]
GO:0007076 [mitotic chromosome condensation]
GO:0008017 [microtubule binding]
GO:0040001 [establishment of mitotic spindle localization]
GO:0045840 [positive regulation of mitotic nuclear division]
GO:0051301 [cell division]
GO:0072686 [mitotic spindle]
Show all
441 aa
49.5 kDa
No 0
NUSAP1-210
ENSP00000453657
ENST00000560177
Q9BXS6
[Direct mapping] Nucleolar and spindle-associated protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000281 [mitotic cytokinesis]
GO:0003677 [DNA binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0005856 [cytoskeleton]
GO:0005874 [microtubule]
GO:0007049 [cell cycle]
GO:0007076 [mitotic chromosome condensation]
GO:0008017 [microtubule binding]
GO:0040001 [establishment of mitotic spindle localization]
GO:0045840 [positive regulation of mitotic nuclear division]
GO:0051301 [cell division]
GO:0072686 [mitotic spindle]
Show all
440 aa
49.3 kDa
No 0
NUSAP1-212
ENSP00000454097
ENST00000560747
Q9BXS6
[Direct mapping] Nucleolar and spindle-associated protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000281 [mitotic cytokinesis]
GO:0003677 [DNA binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0005856 [cytoskeleton]
GO:0005874 [microtubule]
GO:0007049 [cell cycle]
GO:0007076 [mitotic chromosome condensation]
GO:0008017 [microtubule binding]
GO:0040001 [establishment of mitotic spindle localization]
GO:0045840 [positive regulation of mitotic nuclear division]
GO:0051301 [cell division]
GO:0072686 [mitotic spindle]
Show all
439 aa
49.2 kDa
No 0
NUSAP1-214
ENSP00000499238
ENST00000668273
Q9BXS6
[Direct mapping] Nucleolar and spindle-associated protein 1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000226 [microtubule cytoskeleton organization]
GO:0000281 [mitotic cytokinesis]
GO:0003677 [DNA binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0005856 [cytoskeleton]
GO:0005874 [microtubule]
GO:0007049 [cell cycle]
GO:0007076 [mitotic chromosome condensation]
GO:0008017 [microtubule binding]
GO:0040001 [establishment of mitotic spindle localization]
GO:0045840 [positive regulation of mitotic nuclear division]
GO:0051301 [cell division]
GO:0072686 [mitotic spindle]
Show all
441 aa
49.5 kDa
No 0

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