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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:57.4 nTPM
HPA Brain:104.8 nTPM
GTEx:57.4 nTPM
FANTOM5:83.6 Scaled Tags Per Million
Pig:121.4 nTPM
Mouse:214.4 nTPM
Allen mouse:15.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

104.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 73.2
2019 Male, age 18, unknown 96.9
2411 Female, age 72, unknown 90.1
1827 Male, age 72, unknown 82.1
2219 Male, age 76, both hemispheres 79.6
2828 Female, age 72, unknown 70.9
1833 Male, age 53, unknown 68.1
1830 Male, age 51, unknown 67.7
1870 Female, age 42, unknown 66.5
2666 Male, age 74, left hemisphere 62.7
2586 Male, age 75, left hemisphere 47.1
Dorsal raphe nucleus
nTPM: 74.7
2750 Male, age 76, both hemispheres 97.1
2298 Female, age 72, unknown 89.3
2047 Male, age 72, unknown 76.3
1828 Male, age 53, unknown 63.0
2016 Female, age 72, unknown 47.8
Inferior colliculus
nTPM: 62.0
2097 Female, age 72, unknown 81.4
1890 Male, age 53, unknown 62.4
1848 Female, age 42, unknown 59.8
2849 Male, age 72, unknown 44.4
Median raphe nucleus
nTPM: 104.8
2220 Male, age 76, midline 104.8
Periaquaductal grey, anterior
nTPM: 82.4
1947 Male, age 18, unknown 84.8
2502 Female, age 75, unknown 81.4
1795 Male, age 51, unknown 81.0
Periaquaductal grey, dorsal
nTPM: 53.4
2464 Female, age 72, unknown 61.6
1831 Male, age 72, unknown 58.1
1840 Male, age 53, unknown 48.4
2850 Male, age 76, both hemispheres 45.5
Periaquaductal grey, lateral
nTPM: 54.9
2272 Male, age 74, both hemispheres 61.8
2053 Male, age 18, unknown 60.5
2140 Male, age 76, both hemispheres 42.4
Pretectal area
nTPM: 88.0
2007 Male, age 72, unknown 125.5
1816 Male, age 51, unknown 125.3
1944 Female, age 72, unknown 124.7
1817 Female, age 42, unknown 115.3
1815 Male, age 53, unknown 111.0
2667 Female, age 75, unknown 72.5
2273 Male, age 74, both hemispheres 66.3
2224 Female, age 72, unknown 63.5
2407 Male, age 75, both hemispheres 55.8
2825 Male, age 18, unknown 54.2
2316 Male, age 76, right hemisphere 54.0
Red nucleus
nTPM: 78.3
1821 Female, age 72, unknown 102.2
2725 Female, age 75, unknown 90.8
1865 Male, age 51, unknown 88.3
2785 Male, age 18, unknown 85.7
2503 Female, age 72, unknown 85.3
1904 Male, age 53, unknown 81.8
2588 Male, age 74, left hemisphere 75.1
1954 Female, age 42, unknown 73.1
2823 Male, age 76, right hemisphere 73.1
2227 Male, age 72, unknown 62.6
2769 Male, age 72, unknown 62.6
2584 Male, age 75, left hemisphere 58.9
Substantia nigra
nTPM: 92.7
1916 Female, age 42, unknown 124.1
1889 Female, age 72, unknown 108.1
1851 Male, age 51, unknown 107.3
1941 Male, age 53, unknown 104.9
2409 Female, age 72, unknown 104.5
2241 Male, age 72, unknown 101.1
2590 Female, age 75, unknown 75.4
2665 Male, age 74, both hemispheres 68.5
2583 Male, age 75, right hemisphere 68.4
2699 Male, age 18, unknown 64.8
Superior colliculus
nTPM: 77.9
2087 Female, age 72, unknown 108.0
2261 Male, age 18, unknown 94.4
2668 Female, age 75, unknown 89.9
1796 Male, age 53, unknown 79.2
2587 Male, age 74, left hemisphere 78.7
1913 Female, age 42, unknown 77.6
1895 Male, age 76, right hemisphere 76.4
1995 Male, age 72, unknown 70.7
1839 Male, age 51, unknown 54.6
2664 Male, age 75, both hemispheres 50.0
Ventral tegmental area
nTPM: 83.0
2410 Female, age 72, unknown 118.6
2218 Male, age 76, both hemispheres 103.8
1915 Female, age 42, unknown 85.3
2223 Female, age 72, unknown 71.0
2021 Male, age 53, unknown 60.4
1942 Male, age 51, unknown 58.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 57.4
Samples: 139

Max nTPM: 147.1
Min nTPM: 16.8
Std nTPM: 22.8
Median nTPM: 52.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 147.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 144.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 141.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 129.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 102.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 100.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 98.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 97.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 96.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 94.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 91.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 89.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 89.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 88.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 84.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 81.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 80.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 80.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 79.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 78.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 78.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 76.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 75.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 74.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 73.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 72.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 71.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 71.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 71.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 70.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 70.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 69.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 69.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 68.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 68.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 66.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 66.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 66.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 66.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 65.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 65.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 64.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 64.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 63.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 62.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 62.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 62.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 62.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 62.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 62.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 61.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 61.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 59.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 58.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 57.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 57.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 57.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 56.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 56.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 54.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 53.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 53.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 53.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 53.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 52.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 52.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 52.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 52.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 52.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 51.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 51.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 50.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 50.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 50.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 49.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 49.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 49.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 49.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 48.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 48.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 48.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 47.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 47.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 47.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 46.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 45.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 45.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 45.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 45.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 45.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 44.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 44.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 44.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 44.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 43.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 43.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 43.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 43.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 42.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 42.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 42.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 42.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 42.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 42.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 41.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 41.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 40.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 40.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 40.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 40.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 40.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 40.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 39.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 39.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 39.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 39.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 39.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 39.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 38.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 38.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 37.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 34.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 34.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 33.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 33.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 33.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 32.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 31.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 30.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 30.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 30.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 29.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 28.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 27.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 24.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 23.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 16.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

83.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 83.6
FF:10158-103A5 76 years, female 83.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

121.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 109.9
Samples: 4

Max nTPM: 150.6
Min nTPM: 64.0
Sample A Female 140.9
Sample B Female 84.2
Sample C Male 150.6
Sample D Male 64.0
Midbrain
nTPM: 121.5
Samples: 4

Max nTPM: 172.5
Min nTPM: 86.8
Sample A Female 110.0
Sample B Female 86.8
Sample C Male 172.5
Sample D Male 116.5
Periaqueductal gray
nTPM: 68.1
Samples: 3

Max nTPM: 80.5
Min nTPM: 59.6
Sample B Female 64.2
Sample C Male 80.5
Sample D Male 59.6
Superior colliculi
nTPM: 113.6
Samples: 4

Max nTPM: 166.7
Min nTPM: 74.8
Sample A Female 101.8
Sample B Female 74.8
Sample C Male 166.7
Sample D Male 111.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

214.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 214.5
Samples: 4

Max nTPM: 236.7
Min nTPM: 198.2
Sample A Male 198.2
Sample B Male 211.7
Sample C Female 236.7
Sample D Female 211.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.8
71608200 Antisense, RP_050927_01_A08, Mouse strain C57BL/6J (56 days, male) 16.6
654924 Antisense, RP_040922_01_A10, Mouse strain C57BL/6J (56 days, male) 15.0

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