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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:40.4 nTPM
HPA Brain:116.6 nTPM
GTEx:40.4 nTPM
FANTOM5:41.8 Scaled Tags Per Million
Pig:95.4 nTPM
Mouse:95.5 nTPM
Allen mouse:3.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

116.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 89.2
1827 Male, age 72, unknown 102.8
2411 Female, age 72, unknown 99.3
2666 Male, age 74, left hemisphere 98.9
2219 Male, age 76, both hemispheres 94.3
2019 Male, age 18, unknown 93.2
1870 Female, age 42, unknown 89.4
1833 Male, age 53, unknown 84.5
1830 Male, age 51, unknown 78.2
2828 Female, age 72, unknown 77.8
2586 Male, age 75, left hemisphere 73.3
Dorsal raphe nucleus
nTPM: 104.4
2047 Male, age 72, unknown 125.4
2298 Female, age 72, unknown 110.0
2750 Male, age 76, both hemispheres 106.9
1828 Male, age 53, unknown 105.7
2016 Female, age 72, unknown 73.9
Inferior colliculus
nTPM: 86.9
1848 Female, age 42, unknown 94.8
2097 Female, age 72, unknown 88.6
2849 Male, age 72, unknown 87.9
1890 Male, age 53, unknown 76.3
Median raphe nucleus
nTPM: 116.6
2220 Male, age 76, midline 116.6
Periaquaductal grey, anterior
nTPM: 101.3
1947 Male, age 18, unknown 113.0
2502 Female, age 75, unknown 99.8
1795 Male, age 51, unknown 91.2
Periaquaductal grey, dorsal
nTPM: 86.7
1840 Male, age 53, unknown 89.9
1831 Male, age 72, unknown 87.8
2850 Male, age 76, both hemispheres 86.4
2464 Female, age 72, unknown 82.6
Periaquaductal grey, lateral
nTPM: 74.2
2140 Male, age 76, both hemispheres 78.5
2053 Male, age 18, unknown 77.6
2272 Male, age 74, both hemispheres 66.6
Pretectal area
nTPM: 99.7
1816 Male, age 51, unknown 128.0
1944 Female, age 72, unknown 119.1
2007 Male, age 72, unknown 117.0
1817 Female, age 42, unknown 111.7
1815 Male, age 53, unknown 104.1
2667 Female, age 75, unknown 102.1
2224 Female, age 72, unknown 96.4
2273 Male, age 74, both hemispheres 85.8
2825 Male, age 18, unknown 83.4
2407 Male, age 75, both hemispheres 77.8
2316 Male, age 76, right hemisphere 71.8
Red nucleus
nTPM: 80.7
1821 Female, age 72, unknown 104.5
2725 Female, age 75, unknown 91.2
2588 Male, age 74, left hemisphere 84.7
2785 Male, age 18, unknown 82.6
1865 Male, age 51, unknown 81.6
1954 Female, age 42, unknown 81.4
2823 Male, age 76, right hemisphere 79.2
2503 Female, age 72, unknown 77.1
2769 Male, age 72, unknown 74.1
2227 Male, age 72, unknown 73.9
2584 Male, age 75, left hemisphere 69.5
1904 Male, age 53, unknown 68.6
Substantia nigra
nTPM: 107.1
1941 Male, age 53, unknown 145.2
1916 Female, age 42, unknown 141.2
2409 Female, age 72, unknown 125.4
1851 Male, age 51, unknown 117.5
1889 Female, age 72, unknown 117.0
2241 Male, age 72, unknown 107.5
2699 Male, age 18, unknown 92.2
2583 Male, age 75, right hemisphere 81.0
2590 Female, age 75, unknown 77.8
2665 Male, age 74, both hemispheres 66.2
Superior colliculus
nTPM: 85.0
1895 Male, age 76, right hemisphere 99.4
2587 Male, age 74, left hemisphere 99.3
2087 Female, age 72, unknown 96.7
2668 Female, age 75, unknown 95.6
1796 Male, age 53, unknown 88.3
2261 Male, age 18, unknown 87.3
1839 Male, age 51, unknown 85.6
2664 Male, age 75, both hemispheres 73.9
1913 Female, age 42, unknown 69.2
1995 Male, age 72, unknown 54.6
Ventral tegmental area
nTPM: 98.0
2218 Male, age 76, both hemispheres 120.2
2410 Female, age 72, unknown 117.9
1915 Female, age 42, unknown 103.9
2223 Female, age 72, unknown 86.6
2021 Male, age 53, unknown 80.5
1942 Male, age 51, unknown 78.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 40.4
Samples: 139

Max nTPM: 140.7
Min nTPM: 16.0
Std nTPM: 20.3
Median nTPM: 34.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 140.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 124.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 112.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 98.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 83.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 79.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 72.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 72.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 71.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 65.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 64.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 64.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 64.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 63.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 63.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 62.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 61.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 61.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 59.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 58.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 58.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 58.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 57.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 56.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 56.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 55.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 53.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 53.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 53.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 53.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 53.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 52.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 52.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 52.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 52.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 50.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 50.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 49.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 49.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 47.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 47.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 46.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 45.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 45.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 44.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 43.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 43.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 42.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 42.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 42.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 42.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 42.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 41.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 41.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 41.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 40.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 39.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 39.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 38.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 38.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 38.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 37.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 36.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 36.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 36.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 35.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 34.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 34.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 34.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 34.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 33.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 33.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 33.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 33.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 33.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 33.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 33.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 32.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 32.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 32.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 32.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 31.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 31.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 31.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 31.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 31.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 30.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 30.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 29.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 29.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 29.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 29.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 29.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 29.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 28.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 28.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 28.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 28.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 28.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 28.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 28.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 27.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 27.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 26.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 26.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 26.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 25.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 24.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 24.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 24.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 23.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 23.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 23.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 23.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 23.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 23.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 22.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 22.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 22.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 22.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 21.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 21.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 21.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 21.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 21.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 21.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 20.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 20.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 20.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 19.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 19.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 18.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 18.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 18.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 17.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 17.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 16.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 16.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 16.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

41.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 41.8
FF:10158-103A5 76 years, female 41.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 93.6
Samples: 4

Max nTPM: 131.2
Min nTPM: 53.1
Sample A Female 131.2
Sample B Female 67.9
Sample C Male 122.2
Sample D Male 53.1
Midbrain
nTPM: 95.5
Samples: 4

Max nTPM: 111.2
Min nTPM: 76.8
Sample A Female 76.8
Sample B Female 96.5
Sample C Male 111.2
Sample D Male 97.3
Periaqueductal gray
nTPM: 85.9
Samples: 3

Max nTPM: 100.5
Min nTPM: 77.8
Sample B Female 79.3
Sample C Male 100.5
Sample D Male 77.8
Superior colliculi
nTPM: 89.6
Samples: 4

Max nTPM: 128.3
Min nTPM: 46.3
Sample A Female 89.9
Sample B Female 46.3
Sample C Male 128.3
Sample D Male 94.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 95.5
Samples: 4

Max nTPM: 113.2
Min nTPM: 81.5
Sample A Male 81.5
Sample B Male 96.6
Sample C Female 113.2
Sample D Female 90.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.2
70919991 Antisense, RP_050713_02_E03, Mouse strain C57BL/6J (56 days, male) 3.2

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