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  • SUMMARY

  • TISSUE

  • BRAIN

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  • SUBCELL

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  • BLOOD

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PROTEIN SUMMARY GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

SCAPER
Synonyms Zfp291, ZNF291
Gene descriptioni

Full gene name according to HGNC.

S-phase cyclin A associated protein in the ER
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Disease related genes
Human disease related genes
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 15
Cytoband q24.3
Chromosome location (bp) 76347904 - 76905444
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

10
Ensembl ENSG00000140386 (version 109)
Entrez gene 49855
HGNC HGNC:13081
UniProt Q9BY12 (UniProt - Evidence at protein level)
neXtProt NX_Q9BY12
GeneCards SCAPER
Antibodypedia SCAPER antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

CCNA2/CDK2 regulatory protein that transiently maintains CCNA2 in the cytoplasm.... show less
Ligand (UniProt)i

Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.

Metal-binding, Zinc
Gene summary (Entrez)i

Useful information about the gene from Entrez

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
SCAPER-202
ENSP00000326924
ENST00000324767
Q9BY12
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Disease related genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0016607 [nuclear speck]
GO:0046872 [metal ion binding]
GO:0060041 [retina development in camera-type eye]
Show all
1400 aa
158.3 kDa
No 0
SCAPER-203
ENSP00000442190
ENST00000538941
Q9BY12
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Disease related genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0016607 [nuclear speck]
GO:0046872 [metal ion binding]
GO:0060041 [retina development in camera-type eye]
Show all
1154 aa
130.9 kDa
No 0
SCAPER-207
ENSP00000454973
ENST00000563290
Q9BY12
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Disease related genes
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001541 [ovarian follicle development]
GO:0001547 [antral ovarian follicle growth]
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005829 [cytosol]
GO:0007283 [spermatogenesis]
GO:0008270 [zinc ion binding]
GO:0016607 [nuclear speck]
GO:0046872 [metal ion binding]
GO:0060041 [retina development in camera-type eye]
GO:0061827 [sperm head]
GO:0072520 [seminiferous tubule development]
GO:1990917 [ooplasm]
Show all
1400 aa
158.3 kDa
No 0
SCAPER-209
ENSP00000455231
ENST00000563919
H3BPB0
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
111 aa
12.7 kDa
No 0
SCAPER-210
ENSP00000456987
ENST00000564022
H3BT27
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
191 aa
21.1 kDa
No 0
SCAPER-211
ENSP00000457382
ENST00000564177
H3BTY2
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
60 aa
7 kDa
No 0
SCAPER-212
ENSP00000456508
ENST00000564590
H3BS25
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0016607 [nuclear speck]
Show all
767 aa
87.7 kDa
No 0
SCAPER-214
ENSP00000455751
ENST00000565372
H3BQF3
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
154 aa
17.2 kDa
No 0
SCAPER-216
ENSP00000455378
ENST00000565970
H3BPM0
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0005829 [cytosol]
GO:0016607 [nuclear speck]
Show all
747 aa
85.2 kDa
No 0
SCAPER-219
ENSP00000456065
ENST00000568382
H3BR40
[Direct mapping] S phase cyclin A-associated protein in the endoplasmic reticulum
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
115 aa
12.6 kDa
No 0

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