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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
115.2
nTPM
HPA:
115.2
nTPM
GTEx:
98.7
nTPM
FANTOM5:
27.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA041368
Antibody HPA057079
Cholangiocytes
Not detected
Medium
Hepatocytes
Medium
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
115.2
Female, age 60
Liver sample 21 nTPM: 53.2
Male, age 54
Liver sample 23 nTPM: 41.3
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 113.5
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 133.2
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 161.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 101.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 114.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 163.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 130
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 139.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
98.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 98.7
Samples: 226
Max nTPM: 256.6
Min nTPM: 25.2
Std nTPM: 38.3
Median nTPM: 95.0
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
256.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
216.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
199.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
188.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
187.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
184.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
180.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
175.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
175.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
174.2
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
174.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
161.2
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
160.9
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
156.7
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
156.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
154.7
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
154.4
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
149.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
149.4
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
149.4
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
148.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
148.1
GTEX-11ZUS-2526-SM-59872
30-39 years, male
147.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
146.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
145.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
144.8
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
144.1
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
142.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
140.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
140.5
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
139.9
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
138.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
137.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
137.2
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
137.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
137.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
136.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
133.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
132.8
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
132.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
132.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
132.2
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
131.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
131.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
131.3
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
130.0
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
129.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
129.3
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
129.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
128.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
128.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
127.3
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
126.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
126.4
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
125.7
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
125.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
125.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
124.6
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
123.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
123.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
122.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
121.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
121.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
120.7
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
120.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
120.2
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
119.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
117.2
GTEX-14E7W-1526-SM-6871X
70-79 years, male
116.6
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
116.6
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
115.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
114.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
114.3
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
113.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
112.2
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
112.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
111.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
111.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
111.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
110.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
109.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
109.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
108.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
108.4
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
107.5
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
107.0
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
106.9
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
106.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
105.9
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
105.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
105.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
104.6
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
104.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
103.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
103.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
102.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
101.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
101.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
100.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
100.3
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
99.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
99.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
98.7
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
98.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
98.2
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
97.8
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
97.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
96.7
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
96.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
96.1
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
95.8
GTEX-144GL-1426-SM-79OMA
50-59 years, male
95.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
95.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
95.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
94.4
GTEX-18465-1626-SM-7LG6N
50-59 years, male
94.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
94.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
93.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
93.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
93.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
93.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
93.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
92.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
92.1
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
91.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
91.2
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
89.9
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
89.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
88.4
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
88.1
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
85.6
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
85.3
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
85.3
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
85.1
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
84.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
84.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
84.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
84.0
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
84.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
83.8
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
83.6
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
83.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
83.3
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
82.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
82.5
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
82.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
81.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
81.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
81.7
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
81.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
81.3
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
79.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
79.6
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
79.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
79.1
GTEX-1B933-1226-SM-731DW
50-59 years, female
78.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
77.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
76.6
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
76.4
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
75.4
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
74.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
74.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
74.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
73.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
72.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
72.5
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
72.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
71.6
GTEX-1B932-1426-SM-793AN
40-49 years, female
71.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
71.1
GTEX-RU72-1426-SM-46MUF
50-59 years, female
71.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
70.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
69.3
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
67.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
67.0
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
66.9
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
66.9
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
66.5
GTEX-17F96-1226-SM-79OK2
70-79 years, male
66.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
65.5
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
65.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
64.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
63.8
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
63.0
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
62.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
61.9
GTEX-14XAO-0226-SM-68728
60-69 years, female
61.8
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
61.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
60.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
60.1
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
59.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
59.8
GTEX-14PJO-1726-SM-68719
60-69 years, male
59.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
59.0
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
58.5
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
58.0
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
57.1
GTEX-11GSP-0626-SM-5986T
60-69 years, female
55.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
55.6
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
55.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
53.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
52.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
51.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
50.2
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
50.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
49.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
47.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
47.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
46.9
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
46.7
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
45.8
GTEX-Q734-0326-SM-48U15
40-49 years, female
44.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
43.2
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
42.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
42.6
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
39.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
38.7
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
38.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
37.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
36.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
34.9
GTEX-O5YV-0726-SM-EV798
60-69 years, female
33.9
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
32.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
32.0
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
30.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
25.2
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
