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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:87.2 nTPM
HPA Brain:148.1 nTPM
GTEx:87.2 nTPM
FANTOM5:174.7 Scaled Tags Per Million
Pig:137.2 nTPM
Mouse:137.3 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

148.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 117.7
2019 Male, age 18, unknown 155.6
1830 Male, age 51, unknown 133.9
1870 Female, age 42, unknown 130.2
1833 Male, age 53, unknown 129.3
2411 Female, age 72, unknown 126.8
2666 Male, age 74, left hemisphere 112.2
1827 Male, age 72, unknown 107.9
2586 Male, age 75, left hemisphere 104.3
2828 Female, age 72, unknown 97.1
2219 Male, age 76, both hemispheres 79.2
Dorsal raphe nucleus
nTPM: 93.1
2750 Male, age 76, both hemispheres 133.7
1828 Male, age 53, unknown 93.7
2016 Female, age 72, unknown 91.7
2047 Male, age 72, unknown 76.8
2298 Female, age 72, unknown 69.5
Inferior colliculus
nTPM: 96.6
1890 Male, age 53, unknown 102.8
2849 Male, age 72, unknown 97.5
1848 Female, age 42, unknown 94.6
2097 Female, age 72, unknown 91.3
Median raphe nucleus
nTPM: 93.0
2220 Male, age 76, midline 93.0
Periaquaductal grey, anterior
nTPM: 83.3
2502 Female, age 75, unknown 90.9
1947 Male, age 18, unknown 87.3
1795 Male, age 51, unknown 71.5
Periaquaductal grey, dorsal
nTPM: 73.8
2464 Female, age 72, unknown 87.6
1831 Male, age 72, unknown 84.4
2850 Male, age 76, both hemispheres 68.7
1840 Male, age 53, unknown 54.7
Periaquaductal grey, lateral
nTPM: 79.5
2272 Male, age 74, both hemispheres 93.7
2053 Male, age 18, unknown 81.1
2140 Male, age 76, both hemispheres 63.8
Pretectal area
nTPM: 99.0
1817 Female, age 42, unknown 123.8
2007 Male, age 72, unknown 119.8
1815 Male, age 53, unknown 116.9
2407 Male, age 75, both hemispheres 102.2
2316 Male, age 76, right hemisphere 98.6
1944 Female, age 72, unknown 96.7
1816 Male, age 51, unknown 94.0
2273 Male, age 74, both hemispheres 91.8
2825 Male, age 18, unknown 86.7
2667 Female, age 75, unknown 83.4
2224 Female, age 72, unknown 74.8
Red nucleus
nTPM: 148.1
1865 Male, age 51, unknown 181.5
1821 Female, age 72, unknown 173.0
2823 Male, age 76, right hemisphere 161.4
2785 Male, age 18, unknown 157.6
1904 Male, age 53, unknown 155.6
2503 Female, age 72, unknown 152.1
1954 Female, age 42, unknown 148.7
2227 Male, age 72, unknown 142.1
2769 Male, age 72, unknown 138.2
2588 Male, age 74, left hemisphere 133.5
2725 Female, age 75, unknown 127.2
2584 Male, age 75, left hemisphere 106.4
Substantia nigra
nTPM: 98.0
1941 Male, age 53, unknown 113.5
2590 Female, age 75, unknown 112.5
1889 Female, age 72, unknown 112.0
2583 Male, age 75, right hemisphere 110.6
2409 Female, age 72, unknown 103.0
1851 Male, age 51, unknown 97.1
2665 Male, age 74, both hemispheres 89.0
2241 Male, age 72, unknown 83.9
2699 Male, age 18, unknown 83.8
1916 Female, age 42, unknown 74.3
Superior colliculus
nTPM: 108.3
1895 Male, age 76, right hemisphere 129.6
2587 Male, age 74, left hemisphere 127.1
1913 Female, age 42, unknown 125.6
1995 Male, age 72, unknown 119.7
2668 Female, age 75, unknown 113.9
1839 Male, age 51, unknown 104.0
1796 Male, age 53, unknown 94.2
2087 Female, age 72, unknown 92.0
2261 Male, age 18, unknown 89.0
2664 Male, age 75, both hemispheres 88.1
Ventral tegmental area
nTPM: 101.4
2223 Female, age 72, unknown 148.8
2410 Female, age 72, unknown 117.6
2218 Male, age 76, both hemispheres 91.4
1942 Male, age 51, unknown 85.6
1915 Female, age 42, unknown 83.2
2021 Male, age 53, unknown 81.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

87.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 87.2
Samples: 139

Max nTPM: 188.4
Min nTPM: 42.7
Std nTPM: 30.6
Median nTPM: 79.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 188.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 183.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 175.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 166.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 153.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 153.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 152.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 152.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 150.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 146.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 142.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 142.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 141.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 138.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 130.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 127.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 127.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 124.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 124.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 123.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 123.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 117.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 114.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 109.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 108.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 107.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 106.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 105.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 105.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 104.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 102.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 102.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 102.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 100.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 100.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 99.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 98.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 98.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 97.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 97.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 96.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 95.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 94.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 94.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 94.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 92.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 92.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 91.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 91.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 90.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 90.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 90.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 90.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 90.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 89.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 88.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 87.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 86.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 86.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 85.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 85.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 85.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 84.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 83.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 83.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 82.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 82.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 80.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 79.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 79.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 78.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 78.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 78.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 78.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 77.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 77.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 77.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 76.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 76.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 76.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 75.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 75.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 74.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 74.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 74.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 74.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 73.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 72.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 72.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 72.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 71.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 70.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 69.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 69.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 68.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 68.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 67.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 67.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 66.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 65.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 65.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 65.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 65.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 65.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 65.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 64.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 64.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 64.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 63.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 63.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 63.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 62.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 62.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 62.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 61.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 60.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 59.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 59.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 58.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 58.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 58.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 58.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 56.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 56.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 54.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 54.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 53.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 52.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 52.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 51.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 49.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 49.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 48.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 48.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 48.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 47.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 47.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 43.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 42.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

174.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 174.7
FF:10158-103A5 76 years, female 174.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

137.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 110.7
Samples: 4

Max nTPM: 142.9
Min nTPM: 81.2
Sample A Female 126.6
Sample B Female 81.2
Sample C Male 92.2
Sample D Male 142.9
Midbrain
nTPM: 137.2
Samples: 4

Max nTPM: 236.9
Min nTPM: 91.7
Sample A Female 236.9
Sample B Female 115.8
Sample C Male 104.3
Sample D Male 91.7
Periaqueductal gray
nTPM: 80.5
Samples: 3

Max nTPM: 92.4
Min nTPM: 66.9
Sample B Female 92.4
Sample C Male 66.9
Sample D Male 82.2
Superior colliculi
nTPM: 120.0
Samples: 4

Max nTPM: 147.8
Min nTPM: 85.3
Sample A Female 125.0
Sample B Female 85.3
Sample C Male 147.8
Sample D Male 121.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

137.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 137.3
Samples: 4

Max nTPM: 140.4
Min nTPM: 133.0
Sample A Male 137.6
Sample B Male 133.0
Sample C Female 140.4
Sample D Female 138.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
71763540 Antisense, RP_050921_02_B09, Mouse strain C57BL/6J (56 days, male) 0.0

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