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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:68.7 nTPM
HPA Brain:77.9 nTPM
GTEx:68.7 nTPM
FANTOM5:132.0 Scaled Tags Per Million
Pig:58.6 nTPM
Mouse:42.3 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

77.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 66.4
2828 Female, age 72, unknown 94.2
2586 Male, age 75, left hemisphere 90.3
1870 Female, age 42, unknown 68.4
2666 Male, age 74, left hemisphere 68.4
1827 Male, age 72, unknown 64.1
2411 Female, age 72, unknown 61.4
1833 Male, age 53, unknown 61.3
1830 Male, age 51, unknown 61.1
2019 Male, age 18, unknown 53.0
2219 Male, age 76, both hemispheres 41.8
Dorsal raphe nucleus
nTPM: 73.6
2298 Female, age 72, unknown 92.7
1828 Male, age 53, unknown 75.1
2016 Female, age 72, unknown 69.6
2047 Male, age 72, unknown 68.2
2750 Male, age 76, both hemispheres 62.3
Inferior colliculus
nTPM: 69.8
1890 Male, age 53, unknown 73.7
2849 Male, age 72, unknown 68.9
1848 Female, age 42, unknown 68.8
2097 Female, age 72, unknown 67.9
Median raphe nucleus
nTPM: 50.4
2220 Male, age 76, midline 50.4
Periaquaductal grey, anterior
nTPM: 73.9
2502 Female, age 75, unknown 78.0
1795 Male, age 51, unknown 75.4
1947 Male, age 18, unknown 68.2
Periaquaductal grey, dorsal
nTPM: 65.9
2850 Male, age 76, both hemispheres 79.4
1840 Male, age 53, unknown 63.7
2464 Female, age 72, unknown 60.6
1831 Male, age 72, unknown 59.9
Periaquaductal grey, lateral
nTPM: 69.9
2140 Male, age 76, both hemispheres 79.4
2053 Male, age 18, unknown 67.2
2272 Male, age 74, both hemispheres 63.2
Pretectal area
nTPM: 61.8
2316 Male, age 76, right hemisphere 69.9
2825 Male, age 18, unknown 69.2
2224 Female, age 72, unknown 65.5
1817 Female, age 42, unknown 63.9
2007 Male, age 72, unknown 63.9
2667 Female, age 75, unknown 63.8
1816 Male, age 51, unknown 60.3
1944 Female, age 72, unknown 58.0
1815 Male, age 53, unknown 57.4
2273 Male, age 74, both hemispheres 54.5
2407 Male, age 75, both hemispheres 53.5
Red nucleus
nTPM: 77.9
2227 Male, age 72, unknown 88.3
2769 Male, age 72, unknown 87.0
2503 Female, age 72, unknown 83.9
1865 Male, age 51, unknown 82.9
2725 Female, age 75, unknown 82.5
1821 Female, age 72, unknown 82.4
1954 Female, age 42, unknown 81.1
1904 Male, age 53, unknown 77.1
2588 Male, age 74, left hemisphere 72.7
2823 Male, age 76, right hemisphere 69.7
2785 Male, age 18, unknown 69.4
2584 Male, age 75, left hemisphere 58.1
Substantia nigra
nTPM: 66.0
2699 Male, age 18, unknown 88.8
1916 Female, age 42, unknown 79.9
2665 Male, age 74, both hemispheres 71.4
1851 Male, age 51, unknown 69.0
1889 Female, age 72, unknown 64.9
2583 Male, age 75, right hemisphere 64.6
2590 Female, age 75, unknown 63.9
2241 Male, age 72, unknown 57.4
1941 Male, age 53, unknown 51.6
2409 Female, age 72, unknown 48.6
Superior colliculus
nTPM: 64.1
1796 Male, age 53, unknown 82.9
2087 Female, age 72, unknown 67.3
2664 Male, age 75, both hemispheres 66.4
1995 Male, age 72, unknown 64.7
2587 Male, age 74, left hemisphere 63.7
2261 Male, age 18, unknown 63.4
1913 Female, age 42, unknown 63.2
1839 Male, age 51, unknown 58.8
2668 Female, age 75, unknown 55.4
1895 Male, age 76, right hemisphere 54.6
Ventral tegmental area
nTPM: 68.3
1915 Female, age 42, unknown 74.9
2021 Male, age 53, unknown 70.8
2223 Female, age 72, unknown 69.5
1942 Male, age 51, unknown 68.6
2218 Male, age 76, both hemispheres 67.6
2410 Female, age 72, unknown 58.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

68.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 68.7
Samples: 139

Max nTPM: 196.5
Min nTPM: 15.8
Std nTPM: 30.9
Median nTPM: 60.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 196.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 173.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 152.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 136.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 130.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 128.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 124.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 123.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 123.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 121.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 120.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 117.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 117.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 116.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 112.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 106.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 103.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 102.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 101.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 101.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 101.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 101.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 100.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 98.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 95.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 94.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 93.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 91.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 91.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 89.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 87.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 87.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 86.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 85.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 83.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 82.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 82.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 81.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 81.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 80.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 80.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 79.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 79.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 79.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 78.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 77.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 76.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 76.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 76.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 74.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 74.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 73.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 73.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 72.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 71.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 71.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 71.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 71.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 70.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 67.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 66.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 66.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 66.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 64.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 64.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 64.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 61.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 61.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 61.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 60.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 59.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 59.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 59.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 58.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 58.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 57.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 56.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 56.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 56.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 56.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 56.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 55.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 55.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 54.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 54.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 54.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 54.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 54.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 54.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 54.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 52.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 52.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 51.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 51.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 50.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 50.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 49.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 49.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 49.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 48.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 48.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 48.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 47.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 47.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 47.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 46.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 46.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 44.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 44.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 44.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 43.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 42.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 42.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 42.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 41.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 40.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 39.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 38.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 37.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 37.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 37.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 36.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 36.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 35.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 35.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 34.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 34.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 34.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 33.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 33.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 31.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 30.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 29.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 29.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 29.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 28.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 28.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 23.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 15.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

132.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 132.0
FF:10158-103A5 76 years, female 132.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

58.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 58.2
Samples: 4

Max nTPM: 72.5
Min nTPM: 48.9
Sample A Female 60.3
Sample B Female 72.5
Sample C Male 51.2
Sample D Male 48.9
Midbrain
nTPM: 53.3
Samples: 4

Max nTPM: 60.2
Min nTPM: 43.4
Sample A Female 60.2
Sample B Female 59.0
Sample C Male 50.6
Sample D Male 43.4
Periaqueductal gray
nTPM: 53.4
Samples: 3

Max nTPM: 61.1
Min nTPM: 45.7
Sample B Female 53.4
Sample C Male 61.1
Sample D Male 45.7
Superior colliculi
nTPM: 58.6
Samples: 4

Max nTPM: 76.4
Min nTPM: 48.8
Sample A Female 58.7
Sample B Female 76.4
Sample C Male 50.3
Sample D Male 48.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

42.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 42.4
Samples: 4

Max nTPM: 43.9
Min nTPM: 41.1
Sample A Male 42.0
Sample B Male 43.9
Sample C Female 42.4
Sample D Female 41.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
112647104 Antisense, RP_110421_01_A10, Mouse strain C57BL/6J (56 days, male) 1.3
68203510 Antisense, RP_041208_01_E06, Mouse strain C57BL/6J (56 days, male) 0.2

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