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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:106.9 nTPM
HPA Brain:324.1 nTPM
GTEx:106.9 nTPM
FANTOM5:318.8 Scaled Tags Per Million
Pig:60.3 nTPM
Mouse:33.3 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

324.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 274.5
2828 Female, age 72, unknown 406.9
2586 Male, age 75, left hemisphere 360.7
2666 Male, age 74, left hemisphere 288.7
1870 Female, age 42, unknown 285.1
1833 Male, age 53, unknown 268.9
2411 Female, age 72, unknown 265.2
1830 Male, age 51, unknown 261.8
2019 Male, age 18, unknown 255.3
1827 Male, age 72, unknown 239.9
2219 Male, age 76, both hemispheres 112.2
Dorsal raphe nucleus
nTPM: 262.5
2016 Female, age 72, unknown 330.0
1828 Male, age 53, unknown 297.8
2047 Male, age 72, unknown 264.6
2298 Female, age 72, unknown 244.8
2750 Male, age 76, both hemispheres 175.5
Inferior colliculus
nTPM: 265.8
1848 Female, age 42, unknown 280.6
1890 Male, age 53, unknown 276.0
2849 Male, age 72, unknown 264.9
2097 Female, age 72, unknown 241.8
Median raphe nucleus
nTPM: 159.4
2220 Male, age 76, midline 159.4
Periaquaductal grey, anterior
nTPM: 239.3
2502 Female, age 75, unknown 260.0
1947 Male, age 18, unknown 233.6
1795 Male, age 51, unknown 224.4
Periaquaductal grey, dorsal
nTPM: 275.4
2850 Male, age 76, both hemispheres 338.5
2464 Female, age 72, unknown 299.0
1840 Male, age 53, unknown 257.0
1831 Male, age 72, unknown 206.9
Periaquaductal grey, lateral
nTPM: 281.6
2140 Male, age 76, both hemispheres 353.7
2053 Male, age 18, unknown 285.9
2272 Male, age 74, both hemispheres 205.0
Pretectal area
nTPM: 220.7
2316 Male, age 76, right hemisphere 277.6
2825 Male, age 18, unknown 253.9
1817 Female, age 42, unknown 228.4
2407 Male, age 75, both hemispheres 224.4
1815 Male, age 53, unknown 223.9
2667 Female, age 75, unknown 216.5
1944 Female, age 72, unknown 214.4
2273 Male, age 74, both hemispheres 209.6
2224 Female, age 72, unknown 200.6
1816 Male, age 51, unknown 190.0
2007 Male, age 72, unknown 188.8
Red nucleus
nTPM: 324.1
1954 Female, age 42, unknown 391.4
2503 Female, age 72, unknown 383.6
2769 Male, age 72, unknown 365.5
2227 Male, age 72, unknown 358.2
1821 Female, age 72, unknown 349.1
1865 Male, age 51, unknown 336.9
1904 Male, age 53, unknown 323.9
2588 Male, age 74, left hemisphere 316.3
2725 Female, age 75, unknown 301.8
2785 Male, age 18, unknown 279.1
2823 Male, age 76, right hemisphere 263.7
2584 Male, age 75, left hemisphere 219.4
Substantia nigra
nTPM: 271.7
2409 Female, age 72, unknown 337.0
1916 Female, age 42, unknown 318.1
2699 Male, age 18, unknown 313.5
1851 Male, age 51, unknown 294.2
2590 Female, age 75, unknown 272.7
2241 Male, age 72, unknown 254.3
2583 Male, age 75, right hemisphere 247.9
2665 Male, age 74, both hemispheres 230.5
1889 Female, age 72, unknown 225.3
1941 Male, age 53, unknown 223.3
Superior colliculus
nTPM: 247.7
2664 Male, age 75, both hemispheres 328.8
1995 Male, age 72, unknown 326.3
1913 Female, age 42, unknown 259.4
1839 Male, age 51, unknown 248.7
1796 Male, age 53, unknown 245.8
2668 Female, age 75, unknown 237.4
2087 Female, age 72, unknown 219.2
2587 Male, age 74, left hemisphere 216.1
2261 Male, age 18, unknown 209.3
1895 Male, age 76, right hemisphere 185.7
Ventral tegmental area
nTPM: 244.5
2410 Female, age 72, unknown 301.2
1915 Female, age 42, unknown 275.7
1942 Male, age 51, unknown 253.2
2021 Male, age 53, unknown 238.3
2223 Female, age 72, unknown 216.3
2218 Male, age 76, both hemispheres 182.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

106.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 106.9
Samples: 139

Max nTPM: 348.1
Min nTPM: 19.6
Std nTPM: 54.1
Median nTPM: 94.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 348.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 293.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 274.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 255.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 247.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 247.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 231.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 227.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 206.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 200.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 198.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 190.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 176.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 173.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 169.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 169.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 158.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 156.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 152.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 146.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 145.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 144.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 143.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 143.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 142.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 141.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 138.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 134.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 133.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 133.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 133.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 132.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 132.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 129.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 126.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 126.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 125.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 123.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 123.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 120.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 119.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 117.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 117.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 117.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 116.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 115.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 113.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 112.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 112.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 111.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 111.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 109.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 109.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 107.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 107.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 106.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 105.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 104.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 103.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 102.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 101.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 100.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 100.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 99.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 97.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 96.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 96.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 95.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 95.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 94.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 94.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 93.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 93.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 92.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 92.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 89.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 88.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 87.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 86.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 86.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 85.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 84.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 84.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 84.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 84.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 83.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 83.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 81.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 81.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 80.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 80.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 80.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 79.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 79.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 78.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 78.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 77.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 77.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 75.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 75.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 74.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 73.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 73.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 71.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 71.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 71.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 70.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 70.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 69.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 69.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 69.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 68.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 67.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 66.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 66.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 65.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 65.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 62.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 61.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 58.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 58.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 57.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 57.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 57.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 53.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 52.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 52.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 51.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 49.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 49.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 48.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 46.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 44.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 43.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 38.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 37.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 36.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 29.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

318.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 318.8
FF:10158-103A5 76 years, female 318.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

60.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 51.0
Samples: 4

Max nTPM: 56.5
Min nTPM: 46.7
Sample A Female 56.5
Sample B Female 50.3
Sample C Male 50.5
Sample D Male 46.7
Midbrain
nTPM: 59.5
Samples: 4

Max nTPM: 118.0
Min nTPM: 30.4
Sample A Female 118.0
Sample B Female 44.1
Sample C Male 45.6
Sample D Male 30.4
Periaqueductal gray
nTPM: 60.3
Samples: 3

Max nTPM: 63.9
Min nTPM: 56.3
Sample B Female 60.6
Sample C Male 63.9
Sample D Male 56.3
Superior colliculi
nTPM: 45.4
Samples: 4

Max nTPM: 48.1
Min nTPM: 43.0
Sample A Female 47.4
Sample B Female 48.1
Sample C Male 43.0
Sample D Male 43.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

33.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 33.3
Samples: 4

Max nTPM: 35.7
Min nTPM: 30.2
Sample A Male 35.7
Sample B Male 33.0
Sample C Female 30.2
Sample D Female 34.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
69735640 Antisense, RP_050503_03_B11, Mouse strain C57BL/6J (56 days, male) 0.6
73520992 Antisense, RP_051101_02_G11, Mouse strain C57BL/6J (56 days, male) 0.0

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