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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:12.8 nTPM
HPA Brain:18.7 nTPM
GTEx:12.8 nTPM
FANTOM5:69.1 Scaled Tags Per Million
Pig:36.2 nTPM
Mouse:12.7 nTPM
Allen mouse:0.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

18.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 16.2
1870 Female, age 42, unknown 18.5
2411 Female, age 72, unknown 17.5
1833 Male, age 53, unknown 17.4
2019 Male, age 18, unknown 16.9
2586 Male, age 75, left hemisphere 16.7
2666 Male, age 74, left hemisphere 16.2
1830 Male, age 51, unknown 15.8
2828 Female, age 72, unknown 15.1
1827 Male, age 72, unknown 15.0
2219 Male, age 76, both hemispheres 12.4
Dorsal raphe nucleus
nTPM: 15.8
2750 Male, age 76, both hemispheres 17.2
2298 Female, age 72, unknown 16.6
2016 Female, age 72, unknown 15.8
1828 Male, age 53, unknown 15.6
2047 Male, age 72, unknown 13.8
Inferior colliculus
nTPM: 15.1
1848 Female, age 42, unknown 15.9
2849 Male, age 72, unknown 15.4
2097 Female, age 72, unknown 14.9
1890 Male, age 53, unknown 14.3
Median raphe nucleus
nTPM: 15.8
2220 Male, age 76, midline 15.8
Periaquaductal grey, anterior
nTPM: 14.3
1947 Male, age 18, unknown 16.2
2502 Female, age 75, unknown 14.1
1795 Male, age 51, unknown 12.5
Periaquaductal grey, dorsal
nTPM: 14.5
2464 Female, age 72, unknown 15.9
1831 Male, age 72, unknown 14.6
1840 Male, age 53, unknown 14.5
2850 Male, age 76, both hemispheres 13.1
Periaquaductal grey, lateral
nTPM: 13.2
2272 Male, age 74, both hemispheres 16.9
2053 Male, age 18, unknown 12.3
2140 Male, age 76, both hemispheres 10.4
Pretectal area
nTPM: 15.2
2007 Male, age 72, unknown 19.6
1815 Male, age 53, unknown 18.3
1816 Male, age 51, unknown 17.0
2667 Female, age 75, unknown 16.6
1817 Female, age 42, unknown 15.8
2273 Male, age 74, both hemispheres 15.8
1944 Female, age 72, unknown 13.7
2825 Male, age 18, unknown 13.2
2407 Male, age 75, both hemispheres 13.0
2224 Female, age 72, unknown 12.4
2316 Male, age 76, right hemisphere 12.4
Red nucleus
nTPM: 18.7
1821 Female, age 72, unknown 21.3
2588 Male, age 74, left hemisphere 21.3
1865 Male, age 51, unknown 19.8
1904 Male, age 53, unknown 19.4
1954 Female, age 42, unknown 19.1
2769 Male, age 72, unknown 19.0
2584 Male, age 75, left hemisphere 18.8
2725 Female, age 75, unknown 18.7
2227 Male, age 72, unknown 17.9
2503 Female, age 72, unknown 17.6
2785 Male, age 18, unknown 16.5
2823 Male, age 76, right hemisphere 14.8
Substantia nigra
nTPM: 13.9
1889 Female, age 72, unknown 16.2
1916 Female, age 42, unknown 15.9
2699 Male, age 18, unknown 15.4
2583 Male, age 75, right hemisphere 14.4
2590 Female, age 75, unknown 14.4
2665 Male, age 74, both hemispheres 13.7
1941 Male, age 53, unknown 13.3
1851 Male, age 51, unknown 13.1
2241 Male, age 72, unknown 11.4
2409 Female, age 72, unknown 11.1
Superior colliculus
nTPM: 15.6
1995 Male, age 72, unknown 17.6
2664 Male, age 75, both hemispheres 17.1
1895 Male, age 76, right hemisphere 16.2
2087 Female, age 72, unknown 16.1
2261 Male, age 18, unknown 15.8
2587 Male, age 74, left hemisphere 15.4
1839 Male, age 51, unknown 15.2
1796 Male, age 53, unknown 14.8
1913 Female, age 42, unknown 14.6
2668 Female, age 75, unknown 13.6
Ventral tegmental area
nTPM: 15.2
2410 Female, age 72, unknown 18.3
1942 Male, age 51, unknown 15.6
2223 Female, age 72, unknown 15.6
2218 Male, age 76, both hemispheres 14.9
1915 Female, age 42, unknown 13.8
2021 Male, age 53, unknown 12.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 12.8
Samples: 139

Max nTPM: 20.6
Min nTPM: 5.8
Std nTPM: 2.7
Median nTPM: 12.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 20.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 19.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 19.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 18.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 18.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 18.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 18.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 18.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 18.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 17.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 17.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 17.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 17.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 16.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 16.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 16.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 16.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 16.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 16.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 15.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 15.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 15.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 15.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 15.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 15.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 15.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 15.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 14.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 14.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 14.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 14.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 14.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 14.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 14.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 14.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 14.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 14.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 14.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 14.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 14.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 14.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 13.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 13.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 13.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 13.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 13.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 13.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 13.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 13.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 13.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 13.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 13.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 13.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 13.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 13.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 13.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 13.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 12.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 12.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 12.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 12.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 12.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 12.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 12.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 12.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 12.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 12.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 12.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 12.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 12.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 12.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 12.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 12.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 12.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 12.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 12.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 12.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 12.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 12.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 11.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 11.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 11.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 11.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 11.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 11.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 11.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 11.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 11.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 11.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 11.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 11.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 11.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 11.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 11.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 11.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 11.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 11.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 11.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 11.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 11.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 11.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 11.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 11.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 11.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 11.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 11.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 11.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 11.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 11.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 10.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 10.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 10.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 10.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 10.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 10.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 10.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 10.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 10.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 10.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 10.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 10.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 10.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 9.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 9.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 9.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 9.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 9.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 9.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 9.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 9.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 8.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 8.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 8.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 8.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 8.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 7.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 6.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 5.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

69.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 69.1
FF:10158-103A5 76 years, female 69.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

36.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 33.1
Samples: 4

Max nTPM: 38.2
Min nTPM: 28.2
Sample A Female 38.2
Sample B Female 28.2
Sample C Male 35.2
Sample D Male 30.8
Midbrain
nTPM: 36.2
Samples: 4

Max nTPM: 38.8
Min nTPM: 35.0
Sample A Female 35.0
Sample B Female 35.0
Sample C Male 35.9
Sample D Male 38.8
Periaqueductal gray
nTPM: 29.9
Samples: 3

Max nTPM: 31.3
Min nTPM: 29.2
Sample B Female 29.3
Sample C Male 31.3
Sample D Male 29.2
Superior colliculi
nTPM: 35.7
Samples: 4

Max nTPM: 41.3
Min nTPM: 23.5
Sample A Female 41.3
Sample B Female 23.5
Sample C Male 40.4
Sample D Male 37.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 12.7
Samples: 4

Max nTPM: 14.1
Min nTPM: 11.9
Sample A Male 12.7
Sample B Male 11.9
Sample C Female 11.9
Sample D Female 14.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.9
71608393 Antisense, RP_050927_01_F10, Mouse strain C57BL/6J (56 days, male) 1.4
356493 Antisense, RP_040617_02_F08, Mouse strain C57BL/6J (56 days, male) 0.5

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