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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:14.1 nTPM
HPA Brain:25.1 nTPM
GTEx:14.1 nTPM
FANTOM5:52.4 Scaled Tags Per Million
Pig:13.6 nTPM
Mouse:16.1 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

25.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 24.6
2586 Male, age 75, left hemisphere 29.9
2019 Male, age 18, unknown 28.6
1830 Male, age 51, unknown 25.5
1833 Male, age 53, unknown 25.4
2411 Female, age 72, unknown 24.9
1870 Female, age 42, unknown 24.2
2666 Male, age 74, left hemisphere 22.8
2828 Female, age 72, unknown 22.8
1827 Male, age 72, unknown 21.9
2219 Male, age 76, both hemispheres 20.1
Dorsal raphe nucleus
nTPM: 22.7
2750 Male, age 76, both hemispheres 25.0
2016 Female, age 72, unknown 23.0
2047 Male, age 72, unknown 22.6
1828 Male, age 53, unknown 21.9
2298 Female, age 72, unknown 20.7
Inferior colliculus
nTPM: 22.4
1848 Female, age 42, unknown 23.3
2849 Male, age 72, unknown 22.6
1890 Male, age 53, unknown 22.5
2097 Female, age 72, unknown 21.1
Median raphe nucleus
nTPM: 23.5
2220 Male, age 76, midline 23.5
Periaquaductal grey, anterior
nTPM: 22.1
1947 Male, age 18, unknown 23.8
2502 Female, age 75, unknown 22.8
1795 Male, age 51, unknown 19.6
Periaquaductal grey, dorsal
nTPM: 24.3
2850 Male, age 76, both hemispheres 25.9
2464 Female, age 72, unknown 25.1
1831 Male, age 72, unknown 23.9
1840 Male, age 53, unknown 22.1
Periaquaductal grey, lateral
nTPM: 23.4
2272 Male, age 74, both hemispheres 24.6
2140 Male, age 76, both hemispheres 23.6
2053 Male, age 18, unknown 22.1
Pretectal area
nTPM: 22.5
2407 Male, age 75, both hemispheres 26.7
1815 Male, age 53, unknown 24.4
1944 Female, age 72, unknown 23.6
1817 Female, age 42, unknown 23.5
2007 Male, age 72, unknown 23.3
2273 Male, age 74, both hemispheres 22.9
2316 Male, age 76, right hemisphere 21.6
1816 Male, age 51, unknown 21.4
2224 Female, age 72, unknown 21.3
2825 Male, age 18, unknown 20.0
2667 Female, age 75, unknown 18.9
Red nucleus
nTPM: 25.1
2584 Male, age 75, left hemisphere 29.4
1865 Male, age 51, unknown 26.9
2785 Male, age 18, unknown 26.1
1904 Male, age 53, unknown 26.0
2823 Male, age 76, right hemisphere 25.3
2725 Female, age 75, unknown 25.0
1954 Female, age 42, unknown 24.6
2227 Male, age 72, unknown 24.1
1821 Female, age 72, unknown 24.0
2769 Male, age 72, unknown 23.6
2503 Female, age 72, unknown 23.5
2588 Male, age 74, left hemisphere 22.5
Substantia nigra
nTPM: 22.1
2241 Male, age 72, unknown 24.9
2583 Male, age 75, right hemisphere 24.7
1941 Male, age 53, unknown 23.5
2409 Female, age 72, unknown 21.8
2590 Female, age 75, unknown 21.8
1889 Female, age 72, unknown 21.7
1851 Male, age 51, unknown 21.5
1916 Female, age 42, unknown 21.1
2699 Male, age 18, unknown 20.3
2665 Male, age 74, both hemispheres 19.7
Superior colliculus
nTPM: 23.7
2668 Female, age 75, unknown 27.4
1839 Male, age 51, unknown 25.0
1995 Male, age 72, unknown 24.7
1913 Female, age 42, unknown 24.1
1895 Male, age 76, right hemisphere 23.2
2261 Male, age 18, unknown 23.0
2664 Male, age 75, both hemispheres 22.7
1796 Male, age 53, unknown 22.6
2087 Female, age 72, unknown 22.2
2587 Male, age 74, left hemisphere 22.0
Ventral tegmental area
nTPM: 21.9
2223 Female, age 72, unknown 25.2
2410 Female, age 72, unknown 24.3
1942 Male, age 51, unknown 22.2
2021 Male, age 53, unknown 20.5
1915 Female, age 42, unknown 20.3
2218 Male, age 76, both hemispheres 19.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

14.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 14.1
Samples: 139

Max nTPM: 20.1
Min nTPM: 9.9
Std nTPM: 1.8
Median nTPM: 13.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 20.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 20.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 19.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 19.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 18.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 18.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 17.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 17.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 17.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 17.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 17.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 16.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 16.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 16.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 16.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 16.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 16.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 15.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 15.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 15.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 15.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 15.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 15.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 15.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 15.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 15.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 15.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 15.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 15.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 15.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 15.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 15.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 15.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 15.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 14.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 14.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 14.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 14.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 14.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 14.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 14.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 14.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 14.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 14.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 14.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 14.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 14.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 14.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 14.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 14.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 14.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 14.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 14.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 14.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 14.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 14.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 14.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 14.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 14.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 14.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 14.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 14.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 14.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 14.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 14.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 14.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 14.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 13.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 13.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 13.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 13.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 13.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 13.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 13.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 13.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 13.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 13.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 13.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 13.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 13.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 13.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 13.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 13.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 13.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 13.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 13.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 13.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 13.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 13.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 13.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 13.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 13.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 13.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 13.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 13.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 13.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 13.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 13.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 13.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 13.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 13.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 12.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 12.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 12.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 12.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 12.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 12.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 12.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 12.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 12.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 12.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 12.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 12.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 12.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 12.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 12.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 12.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 12.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 12.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 12.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 12.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 12.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 12.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 12.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 12.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 12.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 12.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 12.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 12.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 11.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 11.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 11.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 11.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 11.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 11.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 11.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 10.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 10.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 9.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

52.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 52.4
FF:10158-103A5 76 years, female 52.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

13.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 12.5
Samples: 4

Max nTPM: 14.3
Min nTPM: 11.8
Sample A Female 11.8
Sample B Female 11.8
Sample C Male 12.1
Sample D Male 14.3
Midbrain
nTPM: 13.6
Samples: 4

Max nTPM: 15.8
Min nTPM: 11.9
Sample A Female 15.8
Sample B Female 12.7
Sample C Male 11.9
Sample D Male 13.9
Periaqueductal gray
nTPM: 12.7
Samples: 3

Max nTPM: 13.2
Min nTPM: 11.9
Sample B Female 13.0
Sample C Male 11.9
Sample D Male 13.2
Superior colliculi
nTPM: 11.9
Samples: 4

Max nTPM: 12.9
Min nTPM: 11.2
Sample A Female 11.4
Sample B Female 11.2
Sample C Male 12.2
Sample D Male 12.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 16.1
Samples: 4

Max nTPM: 16.9
Min nTPM: 14.9
Sample A Male 14.9
Sample B Male 16.9
Sample C Female 16.6
Sample D Female 15.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
68799107 Antisense, RP_050217_02_A09, Mouse strain C57BL/6J (56 days, male) 0.7

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