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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:31.2 nTPM
HPA Brain:49.5 nTPM
GTEx:31.2 nTPM
FANTOM5:30.9 Scaled Tags Per Million
Pig:24.7 nTPM
Mouse:16.1 nTPM
Allen mouse:5.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

49.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 42.4
2586 Male, age 75, left hemisphere 54.5
2666 Male, age 74, left hemisphere 50.0
2019 Male, age 18, unknown 47.0
2828 Female, age 72, unknown 41.2
1830 Male, age 51, unknown 39.9
2411 Female, age 72, unknown 39.2
1870 Female, age 42, unknown 39.1
1833 Male, age 53, unknown 38.9
2219 Male, age 76, both hemispheres 38.0
1827 Male, age 72, unknown 36.2
Dorsal raphe nucleus
nTPM: 43.4
1828 Male, age 53, unknown 51.1
2047 Male, age 72, unknown 50.3
2016 Female, age 72, unknown 40.3
2750 Male, age 76, both hemispheres 37.8
2298 Female, age 72, unknown 37.6
Inferior colliculus
nTPM: 37.1
1890 Male, age 53, unknown 39.8
1848 Female, age 42, unknown 37.1
2097 Female, age 72, unknown 35.9
2849 Male, age 72, unknown 35.6
Median raphe nucleus
nTPM: 44.8
2220 Male, age 76, midline 44.8
Periaquaductal grey, anterior
nTPM: 34.6
1795 Male, age 51, unknown 36.2
2502 Female, age 75, unknown 34.9
1947 Male, age 18, unknown 32.6
Periaquaductal grey, dorsal
nTPM: 32.5
2464 Female, age 72, unknown 34.4
1831 Male, age 72, unknown 33.7
1840 Male, age 53, unknown 31.5
2850 Male, age 76, both hemispheres 30.6
Periaquaductal grey, lateral
nTPM: 30.9
2272 Male, age 74, both hemispheres 31.3
2140 Male, age 76, both hemispheres 31.2
2053 Male, age 18, unknown 30.3
Pretectal area
nTPM: 34.8
2407 Male, age 75, both hemispheres 41.7
1817 Female, age 42, unknown 39.2
2007 Male, age 72, unknown 37.6
2667 Female, age 75, unknown 36.1
1816 Male, age 51, unknown 35.4
2825 Male, age 18, unknown 35.0
1944 Female, age 72, unknown 34.9
1815 Male, age 53, unknown 33.6
2224 Female, age 72, unknown 33.3
2316 Male, age 76, right hemisphere 28.8
2273 Male, age 74, both hemispheres 27.7
Red nucleus
nTPM: 43.2
2584 Male, age 75, left hemisphere 48.1
2588 Male, age 74, left hemisphere 48.0
2227 Male, age 72, unknown 46.0
1865 Male, age 51, unknown 45.0
2785 Male, age 18, unknown 44.6
2769 Male, age 72, unknown 43.8
1821 Female, age 72, unknown 42.6
2503 Female, age 72, unknown 41.3
1954 Female, age 42, unknown 41.1
2725 Female, age 75, unknown 41.0
1904 Male, age 53, unknown 40.4
2823 Male, age 76, right hemisphere 36.8
Substantia nigra
nTPM: 49.5
1916 Female, age 42, unknown 61.1
2665 Male, age 74, both hemispheres 59.4
2699 Male, age 18, unknown 57.2
1941 Male, age 53, unknown 54.7
1851 Male, age 51, unknown 49.9
2583 Male, age 75, right hemisphere 49.4
2409 Female, age 72, unknown 46.5
2241 Male, age 72, unknown 40.1
2590 Female, age 75, unknown 39.9
1889 Female, age 72, unknown 37.0
Superior colliculus
nTPM: 36.6
2668 Female, age 75, unknown 44.5
2664 Male, age 75, both hemispheres 42.0
1995 Male, age 72, unknown 37.4
1839 Male, age 51, unknown 36.6
2087 Female, age 72, unknown 36.6
2587 Male, age 74, left hemisphere 36.5
1796 Male, age 53, unknown 35.8
1913 Female, age 42, unknown 35.8
1895 Male, age 76, right hemisphere 32.3
2261 Male, age 18, unknown 28.8
Ventral tegmental area
nTPM: 42.8
1915 Female, age 42, unknown 48.9
2223 Female, age 72, unknown 44.7
2410 Female, age 72, unknown 43.4
2218 Male, age 76, both hemispheres 43.2
1942 Male, age 51, unknown 39.2
2021 Male, age 53, unknown 37.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

31.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 31.2
Samples: 139

Max nTPM: 51.3
Min nTPM: 19.9
Std nTPM: 5.2
Median nTPM: 30.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 51.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 49.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 45.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 44.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 43.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 41.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 41.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 40.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 39.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 39.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 38.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 38.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 37.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 37.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 36.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 36.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 36.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 36.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 36.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 36.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 35.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 35.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 35.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 35.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 35.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 34.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 34.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 34.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 34.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 34.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 34.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 34.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 34.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 34.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 34.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 34.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 34.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 34.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 33.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 33.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 33.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 33.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 33.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 33.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 33.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 33.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 33.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 33.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 33.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 32.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 32.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 32.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 32.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 32.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 32.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 32.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 32.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 31.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 31.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 31.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 31.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 31.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 31.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 31.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 31.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 31.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 31.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 30.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 30.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 30.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 29.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 29.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 29.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 29.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 29.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 29.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 29.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 29.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 29.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 29.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 29.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 29.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 29.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 29.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 29.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 29.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 29.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 29.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 28.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 28.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 28.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 28.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 28.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 28.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 28.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 28.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 28.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 28.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 28.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 27.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 27.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 27.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 27.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 27.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 27.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 26.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 26.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 26.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 26.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 26.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 26.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 26.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 26.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 26.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 26.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 26.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 26.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 26.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 26.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 25.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 25.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 25.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 25.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 25.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 25.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 25.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 25.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 25.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 25.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 24.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 24.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 23.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 23.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 23.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 23.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 22.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 22.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 21.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 19.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

30.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 30.9
FF:10158-103A5 76 years, female 30.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

24.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 24.7
Samples: 4

Max nTPM: 27.0
Min nTPM: 21.3
Sample A Female 26.4
Sample B Female 23.9
Sample C Male 27.0
Sample D Male 21.3
Midbrain
nTPM: 23.5
Samples: 4

Max nTPM: 27.7
Min nTPM: 19.9
Sample A Female 27.7
Sample B Female 22.8
Sample C Male 23.6
Sample D Male 19.9
Periaqueductal gray
nTPM: 20.8
Samples: 3

Max nTPM: 24.0
Min nTPM: 18.1
Sample B Female 20.4
Sample C Male 24.0
Sample D Male 18.1
Superior colliculi
nTPM: 22.9
Samples: 4

Max nTPM: 26.2
Min nTPM: 20.6
Sample A Female 22.4
Sample B Female 20.6
Sample C Male 26.2
Sample D Male 22.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 16.1
Samples: 4

Max nTPM: 17.0
Min nTPM: 15.4
Sample A Male 17.0
Sample B Male 15.9
Sample C Female 15.4
Sample D Female 16.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.8
68443063 Antisense, RP_050111_01_C09, Mouse strain C57BL/6J (56 days, male) 5.8

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