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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:17.9 nTPM
HPA Brain:78.6 nTPM
GTEx:17.9 nTPM
FANTOM5:359.2 Scaled Tags Per Million
Pig:26.2 nTPM
Mouse:7.3 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

78.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 57.7
1830 Male, age 51, unknown 82.1
2219 Male, age 76, both hemispheres 75.7
1833 Male, age 53, unknown 71.2
2411 Female, age 72, unknown 66.0
2019 Male, age 18, unknown 62.7
1870 Female, age 42, unknown 59.2
2828 Female, age 72, unknown 46.1
2666 Male, age 74, left hemisphere 44.0
1827 Male, age 72, unknown 38.3
2586 Male, age 75, left hemisphere 31.2
Dorsal raphe nucleus
nTPM: 40.6
2750 Male, age 76, both hemispheres 83.8
2016 Female, age 72, unknown 41.3
1828 Male, age 53, unknown 38.6
2047 Male, age 72, unknown 22.7
2298 Female, age 72, unknown 16.4
Inferior colliculus
nTPM: 35.6
1890 Male, age 53, unknown 43.4
2849 Male, age 72, unknown 36.9
1848 Female, age 42, unknown 35.8
2097 Female, age 72, unknown 26.3
Median raphe nucleus
nTPM: 41.0
2220 Male, age 76, midline 41.0
Periaquaductal grey, anterior
nTPM: 33.1
2502 Female, age 75, unknown 44.9
1947 Male, age 18, unknown 31.3
1795 Male, age 51, unknown 23.2
Periaquaductal grey, dorsal
nTPM: 25.5
2464 Female, age 72, unknown 41.4
1831 Male, age 72, unknown 27.9
2850 Male, age 76, both hemispheres 18.5
1840 Male, age 53, unknown 14.3
Periaquaductal grey, lateral
nTPM: 25.6
2053 Male, age 18, unknown 31.6
2272 Male, age 74, both hemispheres 29.4
2140 Male, age 76, both hemispheres 15.8
Pretectal area
nTPM: 32.8
2316 Male, age 76, right hemisphere 56.8
1815 Male, age 53, unknown 46.2
2407 Male, age 75, both hemispheres 38.3
2825 Male, age 18, unknown 37.8
2007 Male, age 72, unknown 35.4
1817 Female, age 42, unknown 32.1
2224 Female, age 72, unknown 27.8
2273 Male, age 74, both hemispheres 26.8
1944 Female, age 72, unknown 20.6
2667 Female, age 75, unknown 19.9
1816 Male, age 51, unknown 19.6
Red nucleus
nTPM: 78.6
2823 Male, age 76, right hemisphere 110.9
1865 Male, age 51, unknown 99.5
1904 Male, age 53, unknown 86.3
2503 Female, age 72, unknown 85.0
1821 Female, age 72, unknown 79.7
2785 Male, age 18, unknown 77.8
2227 Male, age 72, unknown 77.0
2769 Male, age 72, unknown 76.6
1954 Female, age 42, unknown 69.5
2588 Male, age 74, left hemisphere 66.6
2725 Female, age 75, unknown 61.8
2584 Male, age 75, left hemisphere 52.4
Substantia nigra
nTPM: 43.3
2409 Female, age 72, unknown 61.8
2590 Female, age 75, unknown 50.8
2583 Male, age 75, right hemisphere 49.6
1851 Male, age 51, unknown 46.0
1889 Female, age 72, unknown 44.0
2241 Male, age 72, unknown 43.8
2699 Male, age 18, unknown 43.1
1941 Male, age 53, unknown 36.4
1916 Female, age 42, unknown 29.9
2665 Male, age 74, both hemispheres 28.1
Superior colliculus
nTPM: 45.6
1913 Female, age 42, unknown 77.6
1995 Male, age 72, unknown 63.7
1895 Male, age 76, right hemisphere 59.9
1839 Male, age 51, unknown 50.3
2587 Male, age 74, left hemisphere 50.1
2668 Female, age 75, unknown 48.6
1796 Male, age 53, unknown 29.5
2664 Male, age 75, both hemispheres 26.3
2087 Female, age 72, unknown 26.0
2261 Male, age 18, unknown 23.6
Ventral tegmental area
nTPM: 47.0
2223 Female, age 72, unknown 66.6
2410 Female, age 72, unknown 61.0
2021 Male, age 53, unknown 41.7
2218 Male, age 76, both hemispheres 40.2
1942 Male, age 51, unknown 39.3
1915 Female, age 42, unknown 33.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

17.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 17.9
Samples: 139

Max nTPM: 65.2
Min nTPM: 2.2
Std nTPM: 10.9
Median nTPM: 15.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 65.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 60.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 47.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 46.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 45.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 44.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 42.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 41.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 37.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 36.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 36.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 35.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 34.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 34.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 33.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 33.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 29.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 29.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 28.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 27.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 27.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 27.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 26.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 26.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 25.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 24.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 24.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 23.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 23.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 23.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 22.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 21.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 21.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 21.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 20.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 20.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 20.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 20.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 20.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 19.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 19.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 19.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 19.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 19.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 19.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 18.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 18.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 18.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 18.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 17.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 17.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 17.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 17.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 16.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 16.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 16.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 16.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 16.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 16.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 16.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 16.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 16.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 16.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 15.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 15.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 15.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 15.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 15.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 15.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 15.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 15.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 15.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 15.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 14.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 14.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 14.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 14.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 14.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 14.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 14.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 14.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 14.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 14.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 13.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 13.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 13.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 13.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 13.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 13.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 13.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 13.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 13.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 13.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 12.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 12.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 12.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 12.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 12.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 12.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 12.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 12.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 11.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 11.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 11.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 10.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 10.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 10.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 10.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 10.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 10.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 10.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 9.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 9.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 9.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 8.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 8.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 8.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 8.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 8.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 7.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 7.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 7.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 7.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 7.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 7.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 6.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 6.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 6.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 6.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 5.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 5.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 5.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 4.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 4.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 4.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 4.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 3.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 3.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 2.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

359.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 359.2
FF:10158-103A5 76 years, female 359.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

26.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 26.2
Samples: 4

Max nTPM: 46.6
Min nTPM: 16.7
Sample A Female 20.1
Sample B Female 16.7
Sample C Male 21.3
Sample D Male 46.6
Midbrain
nTPM: 24.7
Samples: 4

Max nTPM: 41.6
Min nTPM: 14.3
Sample A Female 41.6
Sample B Female 25.2
Sample C Male 14.3
Sample D Male 17.7
Periaqueductal gray
nTPM: 20.1
Samples: 3

Max nTPM: 22.7
Min nTPM: 16.0
Sample B Female 22.7
Sample C Male 16.0
Sample D Male 21.5
Superior colliculi
nTPM: 18.0
Samples: 4

Max nTPM: 24.5
Min nTPM: 10.7
Sample A Female 17.1
Sample B Female 10.7
Sample C Male 19.8
Sample D Male 24.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

7.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 7.3
Samples: 4

Max nTPM: 7.8
Min nTPM: 6.7
Sample A Male 6.8
Sample B Male 6.7
Sample C Female 7.7
Sample D Female 7.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
69290531 Antisense, RP_050407_04_C01, Mouse strain C57BL/6J (56 days, male) 0.9
75038443 Antisense, RP_060412_04_A04, Mouse strain C57BL/6J (56 days, male) 0.1

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