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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:18.7 nTPM
HPA Brain:126.3 nTPM
GTEx:18.7 nTPM
FANTOM5:54.5 Scaled Tags Per Million
Pig:19.8 nTPM
Mouse:16.5 nTPM
Allen mouse:6.3 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

126.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 96.8
2019 Male, age 18, unknown 116.5
2828 Female, age 72, unknown 102.5
1827 Male, age 72, unknown 99.9
1830 Male, age 51, unknown 99.1
1833 Male, age 53, unknown 98.5
2219 Male, age 76, both hemispheres 98.0
2411 Female, age 72, unknown 95.6
2586 Male, age 75, left hemisphere 94.6
2666 Male, age 74, left hemisphere 85.4
1870 Female, age 42, unknown 78.2
Dorsal raphe nucleus
nTPM: 107.3
2016 Female, age 72, unknown 121.4
2047 Male, age 72, unknown 114.8
2298 Female, age 72, unknown 112.5
1828 Male, age 53, unknown 94.7
2750 Male, age 76, both hemispheres 93.1
Inferior colliculus
nTPM: 102.7
1890 Male, age 53, unknown 104.7
2849 Male, age 72, unknown 103.3
2097 Female, age 72, unknown 102.8
1848 Female, age 42, unknown 100.2
Median raphe nucleus
nTPM: 85.9
2220 Male, age 76, midline 85.9
Periaquaductal grey, anterior
nTPM: 102.3
1947 Male, age 18, unknown 110.5
2502 Female, age 75, unknown 98.9
1795 Male, age 51, unknown 97.4
Periaquaductal grey, dorsal
nTPM: 113.2
2850 Male, age 76, both hemispheres 122.8
1831 Male, age 72, unknown 111.1
1840 Male, age 53, unknown 110.6
2464 Female, age 72, unknown 108.2
Periaquaductal grey, lateral
nTPM: 126.3
2272 Male, age 74, both hemispheres 138.4
2140 Male, age 76, both hemispheres 137.4
2053 Male, age 18, unknown 103.2
Pretectal area
nTPM: 109.5
2273 Male, age 74, both hemispheres 141.3
2007 Male, age 72, unknown 128.1
1944 Female, age 72, unknown 121.6
1816 Male, age 51, unknown 117.5
2316 Male, age 76, right hemisphere 110.2
2667 Female, age 75, unknown 105.8
1817 Female, age 42, unknown 104.6
1815 Male, age 53, unknown 101.2
2224 Female, age 72, unknown 99.0
2825 Male, age 18, unknown 89.4
2407 Male, age 75, both hemispheres 85.8
Red nucleus
nTPM: 107.6
1954 Female, age 42, unknown 115.5
2785 Male, age 18, unknown 113.8
1865 Male, age 51, unknown 112.8
2725 Female, age 75, unknown 112.4
2503 Female, age 72, unknown 112.0
2823 Male, age 76, right hemisphere 112.0
1904 Male, age 53, unknown 111.5
2769 Male, age 72, unknown 108.4
2227 Male, age 72, unknown 105.0
2588 Male, age 74, left hemisphere 104.1
1821 Female, age 72, unknown 99.3
2584 Male, age 75, left hemisphere 84.9
Substantia nigra
nTPM: 92.3
1941 Male, age 53, unknown 112.1
1889 Female, age 72, unknown 105.6
2590 Female, age 75, unknown 105.0
2409 Female, age 72, unknown 102.7
1916 Female, age 42, unknown 94.5
2583 Male, age 75, right hemisphere 93.8
2699 Male, age 18, unknown 80.7
1851 Male, age 51, unknown 80.4
2665 Male, age 74, both hemispheres 80.1
2241 Male, age 72, unknown 67.8
Superior colliculus
nTPM: 95.3
2261 Male, age 18, unknown 113.5
2087 Female, age 72, unknown 111.0
1895 Male, age 76, right hemisphere 108.2
1995 Male, age 72, unknown 98.9
1839 Male, age 51, unknown 92.4
1913 Female, age 42, unknown 89.2
2587 Male, age 74, left hemisphere 89.1
1796 Male, age 53, unknown 87.5
2668 Female, age 75, unknown 83.0
2664 Male, age 75, both hemispheres 80.6
Ventral tegmental area
nTPM: 91.4
2410 Female, age 72, unknown 100.6
2218 Male, age 76, both hemispheres 97.3
1942 Male, age 51, unknown 94.6
2021 Male, age 53, unknown 91.3
1915 Female, age 42, unknown 90.3
2223 Female, age 72, unknown 74.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

18.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 18.7
Samples: 139

Max nTPM: 39.1
Min nTPM: 6.6
Std nTPM: 6.1
Median nTPM: 18.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 39.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 36.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 36.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 33.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 29.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 29.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 29.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 29.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 28.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 28.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 27.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 27.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 27.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 26.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 26.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 26.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 25.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 25.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 25.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 25.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 24.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 24.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 24.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 24.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 24.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 23.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 23.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 23.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 23.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 23.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 22.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 22.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 22.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 22.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 22.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 22.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 22.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 22.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 22.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 21.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 21.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 21.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 21.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 21.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 20.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 20.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 20.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 20.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 20.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 20.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 20.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 20.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 19.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 19.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 19.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 19.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 19.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 19.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 19.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 19.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 19.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 19.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 19.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 19.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 19.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 18.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 18.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 18.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 18.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 18.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 18.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 18.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 18.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 18.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 17.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 17.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 17.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 17.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 17.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 17.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 17.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 17.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 17.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 17.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 17.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 17.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 16.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 16.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 16.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 16.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 16.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 15.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 15.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 15.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 15.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 15.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 15.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 15.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 15.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 14.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 14.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 14.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 14.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 14.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 14.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 14.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 14.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 14.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 14.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 14.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 14.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 13.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 13.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 13.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 13.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 13.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 12.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 12.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 12.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 11.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 11.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 11.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 11.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 11.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 11.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 11.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 11.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 10.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 10.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 9.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 9.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 9.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 9.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 9.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 8.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 8.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 7.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 6.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

54.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 54.5
FF:10158-103A5 76 years, female 54.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

19.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 13.4
Samples: 4

Max nTPM: 17.0
Min nTPM: 10.7
Sample A Female 14.5
Sample B Female 10.7
Sample C Male 17.0
Sample D Male 11.2
Midbrain
nTPM: 18.7
Samples: 4

Max nTPM: 24.0
Min nTPM: 13.8
Sample A Female 14.9
Sample B Female 13.8
Sample C Male 21.9
Sample D Male 24.0
Periaqueductal gray
nTPM: 14.0
Samples: 3

Max nTPM: 15.7
Min nTPM: 11.2
Sample B Female 15.0
Sample C Male 15.7
Sample D Male 11.2
Superior colliculi
nTPM: 19.8
Samples: 4

Max nTPM: 28.4
Min nTPM: 12.4
Sample A Female 19.9
Sample B Female 12.4
Sample C Male 28.4
Sample D Male 18.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 16.6
Samples: 4

Max nTPM: 19.2
Min nTPM: 13.2
Sample A Male 13.2
Sample B Male 16.6
Sample C Female 19.2
Sample D Female 17.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.3
70305401 Antisense, RP_050609_04_B02, Mouse strain C57BL/6J (56 days, male) 7.0
74047748 Antisense, RP_051214_01_H04, Mouse strain C57BL/6J (56 days, male) 5.7

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