We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Assigned HPA protein class(es) for the encoded protein(s).
Cancer-related genes Disease related genes Human disease related genes Transcription factors
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
10
Cytoband
Chromosome location (bp)
112950247 - 113167678
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as a repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine....show less
Molecular function (UniProt)i
Keywords assigned by UniProt to proteins due to their particular molecular function.
Activator, DNA-binding, Repressor
Biological process (UniProt)i
Keywords assigned by UniProt to proteins because they are involved in a particular biological process.
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors Other all-alpha-helical DNA-binding domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Human disease related genes Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000785[chromatin] GO:0000976[transcription cis-regulatory region binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001568[blood vessel development] GO:0003676[nucleic acid binding] GO:0003677[DNA binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0006357[regulation of transcription by RNA polymerase II] GO:0008013[beta-catenin binding] GO:0009749[response to glucose] GO:0010909[positive regulation of heparan sulfate proteoglycan biosynthetic process] GO:0016055[Wnt signaling pathway] GO:0016605[PML body] GO:0016922[nuclear receptor binding] GO:0019901[protein kinase binding] GO:0031016[pancreas development] GO:0032024[positive regulation of insulin secretion] GO:0032092[positive regulation of protein binding] GO:0032350[regulation of hormone metabolic process] GO:0032993[protein-DNA complex] GO:0042593[glucose homeostasis] GO:0043433[negative regulation of DNA-binding transcription factor activity] GO:0043565[sequence-specific DNA binding] GO:0043570[maintenance of DNA repeat elements] GO:0044334[canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition] GO:0045295[gamma-catenin binding] GO:0045444[fat cell differentiation] GO:0045892[negative regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0048625[myoblast fate commitment] GO:0048660[regulation of smooth muscle cell proliferation] GO:0050679[positive regulation of epithelial cell proliferation] GO:0051897[positive regulation of protein kinase B signaling] GO:0060070[canonical Wnt signaling pathway] GO:0060090[molecular adaptor activity] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070016[armadillo repeat domain binding] GO:0070369[beta-catenin-TCF7L2 complex] GO:0071664[catenin-TCF7L2 complex] GO:0090090[negative regulation of canonical Wnt signaling pathway] GO:1900182[positive regulation of protein localization to nucleus] GO:1990907[beta-catenin-TCF complex] GO:2000675[negative regulation of type B pancreatic cell apoptotic process] GO:2001237[negative regulation of extrinsic apoptotic signaling pathway]
MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors Other all-alpha-helical DNA-binding domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Human disease related genes Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000785[chromatin] GO:0000976[transcription cis-regulatory region binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001568[blood vessel development] GO:0003676[nucleic acid binding] GO:0003677[DNA binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0006357[regulation of transcription by RNA polymerase II] GO:0008013[beta-catenin binding] GO:0009749[response to glucose] GO:0010909[positive regulation of heparan sulfate proteoglycan biosynthetic process] GO:0016055[Wnt signaling pathway] GO:0016605[PML body] GO:0016922[nuclear receptor binding] GO:0019901[protein kinase binding] GO:0031016[pancreas development] GO:0032024[positive regulation of insulin secretion] GO:0032092[positive regulation of protein binding] GO:0032350[regulation of hormone metabolic process] GO:0032993[protein-DNA complex] GO:0042593[glucose homeostasis] GO:0043433[negative regulation of DNA-binding transcription factor activity] GO:0043565[sequence-specific DNA binding] GO:0043570[maintenance of DNA repeat elements] GO:0044334[canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition] GO:0045295[gamma-catenin binding] GO:0045444[fat cell differentiation] GO:0045892[negative regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0048625[myoblast fate commitment] GO:0048660[regulation of smooth muscle cell proliferation] GO:0050679[positive regulation of epithelial cell proliferation] GO:0051897[positive regulation of protein kinase B signaling] GO:0060070[canonical Wnt signaling pathway] GO:0060090[molecular adaptor activity] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070016[armadillo repeat domain binding] GO:0070369[beta-catenin-TCF7L2 complex] GO:0071664[catenin-TCF7L2 complex] GO:0090090[negative regulation of canonical Wnt signaling pathway] GO:1900182[positive regulation of protein localization to nucleus] GO:1990907[beta-catenin-TCF complex] GO:2000675[negative regulation of type B pancreatic cell apoptotic process] GO:2001237[negative regulation of extrinsic apoptotic signaling pathway]
SCAMPI predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors Other all-alpha-helical DNA-binding domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Human disease related genes Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000785[chromatin] GO:0000976[transcription cis-regulatory region binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001568[blood vessel development] GO:0003676[nucleic acid binding] GO:0003677[DNA binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0006357[regulation of transcription by RNA polymerase II] GO:0008013[beta-catenin binding] GO:0009749[response to glucose] GO:0010909[positive regulation of heparan sulfate proteoglycan biosynthetic process] GO:0016055[Wnt signaling pathway] GO:0016605[PML body] GO:0016922[nuclear receptor binding] GO:0019901[protein kinase binding] GO:0031016[pancreas development] GO:0032024[positive regulation of insulin secretion] GO:0032092[positive regulation of protein binding] GO:0032350[regulation of hormone metabolic process] GO:0032993[protein-DNA complex] GO:0042593[glucose homeostasis] GO:0043433[negative regulation of DNA-binding transcription factor activity] GO:0043565[sequence-specific DNA binding] GO:0043570[maintenance of DNA repeat elements] GO:0044334[canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition] GO:0045295[gamma-catenin binding] GO:0045444[fat cell differentiation] GO:0045892[negative regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0048625[myoblast fate commitment] GO:0048660[regulation of smooth muscle cell proliferation] GO:0050679[positive regulation of epithelial cell proliferation] GO:0051897[positive regulation of protein kinase B signaling] GO:0060070[canonical Wnt signaling pathway] GO:0060090[molecular adaptor activity] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070016[armadillo repeat domain binding] GO:0070369[beta-catenin-TCF7L2 complex] GO:0071664[catenin-TCF7L2 complex] GO:0090090[negative regulation of canonical Wnt signaling pathway] GO:1900182[positive regulation of protein localization to nucleus] GO:1990907[beta-catenin-TCF complex] GO:2000675[negative regulation of type B pancreatic cell apoptotic process] GO:2001237[negative regulation of extrinsic apoptotic signaling pathway]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors Other all-alpha-helical DNA-binding domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Human disease related genes Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000785[chromatin] GO:0000976[transcription cis-regulatory region binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001568[blood vessel development] GO:0003676[nucleic acid binding] GO:0003677[DNA binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0006357[regulation of transcription by RNA polymerase II] GO:0008013[beta-catenin binding] GO:0009749[response to glucose] GO:0010909[positive regulation of heparan sulfate proteoglycan biosynthetic process] GO:0016055[Wnt signaling pathway] GO:0016605[PML body] GO:0016922[nuclear receptor binding] GO:0019901[protein kinase binding] GO:0031016[pancreas development] GO:0032024[positive regulation of insulin secretion] GO:0032092[positive regulation of protein binding] GO:0032350[regulation of hormone metabolic process] GO:0032993[protein-DNA complex] GO:0042593[glucose homeostasis] GO:0043433[negative regulation of DNA-binding transcription factor activity] GO:0043565[sequence-specific DNA binding] GO:0043570[maintenance of DNA repeat elements] GO:0044334[canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition] GO:0045295[gamma-catenin binding] GO:0045444[fat cell differentiation] GO:0045892[negative regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0048625[myoblast fate commitment] GO:0048660[regulation of smooth muscle cell proliferation] GO:0050679[positive regulation of epithelial cell proliferation] GO:0051897[positive regulation of protein kinase B signaling] GO:0060070[canonical Wnt signaling pathway] GO:0060090[molecular adaptor activity] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070016[armadillo repeat domain binding] GO:0070369[beta-catenin-TCF7L2 complex] GO:0071664[catenin-TCF7L2 complex] GO:0090090[negative regulation of canonical Wnt signaling pathway] GO:1900182[positive regulation of protein localization to nucleus] GO:1990907[beta-catenin-TCF complex] GO:2000675[negative regulation of type B pancreatic cell apoptotic process] GO:2001237[negative regulation of extrinsic apoptotic signaling pathway]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
SCAMPI predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors Other all-alpha-helical DNA-binding domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Human disease related genes Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000785[chromatin] GO:0000976[transcription cis-regulatory region binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001568[blood vessel development] GO:0003676[nucleic acid binding] GO:0003677[DNA binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0006357[regulation of transcription by RNA polymerase II] GO:0008013[beta-catenin binding] GO:0009749[response to glucose] GO:0010909[positive regulation of heparan sulfate proteoglycan biosynthetic process] GO:0016055[Wnt signaling pathway] GO:0016605[PML body] GO:0016922[nuclear receptor binding] GO:0019901[protein kinase binding] GO:0031016[pancreas development] GO:0032024[positive regulation of insulin secretion] GO:0032092[positive regulation of protein binding] GO:0032350[regulation of hormone metabolic process] GO:0032993[protein-DNA complex] GO:0042593[glucose homeostasis] GO:0043433[negative regulation of DNA-binding transcription factor activity] GO:0043565[sequence-specific DNA binding] GO:0043570[maintenance of DNA repeat elements] GO:0044334[canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition] GO:0045295[gamma-catenin binding] GO:0045444[fat cell differentiation] GO:0045892[negative regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0048625[myoblast fate commitment] GO:0048660[regulation of smooth muscle cell proliferation] GO:0050679[positive regulation of epithelial cell proliferation] GO:0051897[positive regulation of protein kinase B signaling] GO:0060070[canonical Wnt signaling pathway] GO:0060090[molecular adaptor activity] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070016[armadillo repeat domain binding] GO:0070369[beta-catenin-TCF7L2 complex] GO:0071664[catenin-TCF7L2 complex] GO:0090090[negative regulation of canonical Wnt signaling pathway] GO:1900182[positive regulation of protein localization to nucleus] GO:1990907[beta-catenin-TCF complex] GO:2000675[negative regulation of type B pancreatic cell apoptotic process] GO:2001237[negative regulation of extrinsic apoptotic signaling pathway]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
SCAMPI predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors Other all-alpha-helical DNA-binding domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Human disease related genes Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122[negative regulation of transcription by RNA polymerase II] GO:0000785[chromatin] GO:0000976[transcription cis-regulatory region binding] GO:0000978[RNA polymerase II cis-regulatory region sequence-specific DNA binding] GO:0000981[DNA-binding transcription factor activity, RNA polymerase II-specific] GO:0001568[blood vessel development] GO:0003676[nucleic acid binding] GO:0003677[DNA binding] GO:0003700[DNA-binding transcription factor activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0006357[regulation of transcription by RNA polymerase II] GO:0008013[beta-catenin binding] GO:0009749[response to glucose] GO:0010909[positive regulation of heparan sulfate proteoglycan biosynthetic process] GO:0016055[Wnt signaling pathway] GO:0016605[PML body] GO:0016922[nuclear receptor binding] GO:0019901[protein kinase binding] GO:0031016[pancreas development] GO:0032024[positive regulation of insulin secretion] GO:0032092[positive regulation of protein binding] GO:0032350[regulation of hormone metabolic process] GO:0032993[protein-DNA complex] GO:0042593[glucose homeostasis] GO:0043433[negative regulation of DNA-binding transcription factor activity] GO:0043565[sequence-specific DNA binding] GO:0043570[maintenance of DNA repeat elements] GO:0044334[canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition] GO:0045295[gamma-catenin binding] GO:0045444[fat cell differentiation] GO:0045892[negative regulation of DNA-templated transcription] GO:0045944[positive regulation of transcription by RNA polymerase II] GO:0048625[myoblast fate commitment] GO:0048660[regulation of smooth muscle cell proliferation] GO:0050679[positive regulation of epithelial cell proliferation] GO:0051897[positive regulation of protein kinase B signaling] GO:0060070[canonical Wnt signaling pathway] GO:0060090[molecular adaptor activity] GO:0061629[RNA polymerase II-specific DNA-binding transcription factor binding] GO:0070016[armadillo repeat domain binding] GO:0070369[beta-catenin-TCF7L2 complex] GO:0071664[catenin-TCF7L2 complex] GO:0090090[negative regulation of canonical Wnt signaling pathway] GO:1900182[positive regulation of protein localization to nucleus] GO:1990907[beta-catenin-TCF complex] GO:2000675[negative regulation of type B pancreatic cell apoptotic process] GO:2001237[negative regulation of extrinsic apoptotic signaling pathway]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Human disease related genes Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
The Human Protein Atlas project is funded
