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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:40.9 nTPM
HPA Brain:97.9 nTPM
GTEx:40.9 nTPM
FANTOM5:222.9 Scaled Tags Per Million
Pig:39.5 nTPM
Mouse:103.9 nTPM
Allen mouse:8.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

97.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 79.5
2411 Female, age 72, unknown 106.2
1870 Female, age 42, unknown 103.1
2019 Male, age 18, unknown 96.7
1830 Male, age 51, unknown 89.3
1833 Male, age 53, unknown 88.5
2828 Female, age 72, unknown 69.4
2586 Male, age 75, left hemisphere 65.9
2219 Male, age 76, both hemispheres 62.0
1827 Male, age 72, unknown 60.7
2666 Male, age 74, left hemisphere 53.0
Dorsal raphe nucleus
nTPM: 75.8
2750 Male, age 76, both hemispheres 102.2
1828 Male, age 53, unknown 74.6
2016 Female, age 72, unknown 70.0
2298 Female, age 72, unknown 66.4
2047 Male, age 72, unknown 65.5
Inferior colliculus
nTPM: 63.5
1848 Female, age 42, unknown 70.9
2097 Female, age 72, unknown 62.4
2849 Male, age 72, unknown 61.3
1890 Male, age 53, unknown 59.3
Median raphe nucleus
nTPM: 80.6
2220 Male, age 76, midline 80.6
Periaquaductal grey, anterior
nTPM: 61.0
2502 Female, age 75, unknown 65.6
1947 Male, age 18, unknown 64.0
1795 Male, age 51, unknown 53.5
Periaquaductal grey, dorsal
nTPM: 58.1
2464 Female, age 72, unknown 67.4
2850 Male, age 76, both hemispheres 61.6
1840 Male, age 53, unknown 53.9
1831 Male, age 72, unknown 49.4
Periaquaductal grey, lateral
nTPM: 61.4
2272 Male, age 74, both hemispheres 63.0
2140 Male, age 76, both hemispheres 62.8
2053 Male, age 18, unknown 58.4
Pretectal area
nTPM: 64.1
2316 Male, age 76, right hemisphere 74.4
2007 Male, age 72, unknown 72.4
1815 Male, age 53, unknown 71.4
1817 Female, age 42, unknown 70.2
2667 Female, age 75, unknown 70.2
2825 Male, age 18, unknown 64.6
2224 Female, age 72, unknown 62.3
2273 Male, age 74, both hemispheres 60.7
1944 Female, age 72, unknown 57.1
1816 Male, age 51, unknown 51.0
2407 Male, age 75, both hemispheres 50.3
Red nucleus
nTPM: 97.9
1821 Female, age 72, unknown 122.8
1865 Male, age 51, unknown 113.2
1904 Male, age 53, unknown 109.5
2227 Male, age 72, unknown 102.5
1954 Female, age 42, unknown 101.2
2769 Male, age 72, unknown 100.8
2823 Male, age 76, right hemisphere 100.8
2503 Female, age 72, unknown 99.9
2785 Male, age 18, unknown 94.7
2588 Male, age 74, left hemisphere 84.6
2725 Female, age 75, unknown 81.9
2584 Male, age 75, left hemisphere 63.2
Substantia nigra
nTPM: 80.5
2409 Female, age 72, unknown 101.9
2241 Male, age 72, unknown 91.4
1851 Male, age 51, unknown 91.2
1941 Male, age 53, unknown 86.2
2583 Male, age 75, right hemisphere 77.5
1916 Female, age 42, unknown 77.1
1889 Female, age 72, unknown 77.0
2590 Female, age 75, unknown 75.0
2699 Male, age 18, unknown 73.1
2665 Male, age 74, both hemispheres 54.1
Superior colliculus
nTPM: 67.5
1913 Female, age 42, unknown 91.4
1995 Male, age 72, unknown 79.7
1895 Male, age 76, right hemisphere 76.3
2587 Male, age 74, left hemisphere 73.8
1839 Male, age 51, unknown 70.5
2668 Female, age 75, unknown 69.4
1796 Male, age 53, unknown 59.2
2261 Male, age 18, unknown 57.5
2087 Female, age 72, unknown 55.1
2664 Male, age 75, both hemispheres 42.0
Ventral tegmental area
nTPM: 83.3
2410 Female, age 72, unknown 103.3
2223 Female, age 72, unknown 97.0
2218 Male, age 76, both hemispheres 84.2
1915 Female, age 42, unknown 78.6
1942 Male, age 51, unknown 70.1
2021 Male, age 53, unknown 66.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 40.9
Samples: 139

Max nTPM: 94.6
Min nTPM: 19.2
Std nTPM: 14.1
Median nTPM: 38.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 94.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 94.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 92.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 85.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 83.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 81.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 77.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 71.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 64.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 61.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 59.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 57.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 56.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 55.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 55.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 54.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 52.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 52.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 51.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 51.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 50.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 50.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 49.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 49.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 49.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 48.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 48.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 47.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 47.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 47.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 47.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 47.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 47.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 46.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 46.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 46.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 45.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 45.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 44.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 44.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 44.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 43.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 43.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 43.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 43.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 42.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 42.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 41.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 41.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 41.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 41.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 41.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 40.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 40.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 40.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 40.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 40.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 40.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 40.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 39.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 39.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 39.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 39.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 38.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 38.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 38.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 38.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 38.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 38.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 38.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 38.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 38.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 37.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 37.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 37.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 37.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 36.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 36.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 36.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 35.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 35.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 35.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 35.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 35.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 35.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 35.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 34.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 34.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 34.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 34.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 34.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 33.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 33.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 33.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 33.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 33.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 32.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 32.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 32.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 32.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 32.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 32.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 32.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 32.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 32.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 31.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 31.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 31.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 31.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 30.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 30.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 30.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 30.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 30.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 29.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 29.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 29.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 29.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 29.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 29.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 29.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 29.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 28.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 28.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 28.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 28.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 27.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 27.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 27.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 27.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 26.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 26.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 26.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 23.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 22.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 21.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 21.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 20.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 19.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

222.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 222.9
FF:10158-103A5 76 years, female 222.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

39.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 27.4
Samples: 4

Max nTPM: 35.2
Min nTPM: 20.8
Sample A Female 35.2
Sample B Female 20.8
Sample C Male 26.7
Sample D Male 27.0
Midbrain
nTPM: 36.3
Samples: 4

Max nTPM: 58.1
Min nTPM: 19.6
Sample A Female 43.2
Sample B Female 24.3
Sample C Male 58.1
Sample D Male 19.6
Periaqueductal gray
nTPM: 18.8
Samples: 3

Max nTPM: 21.1
Min nTPM: 16.7
Sample B Female 21.1
Sample C Male 18.5
Sample D Male 16.7
Superior colliculi
nTPM: 39.5
Samples: 4

Max nTPM: 73.2
Min nTPM: 24.7
Sample A Female 29.9
Sample B Female 24.7
Sample C Male 73.2
Sample D Male 30.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

103.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 103.9
Samples: 4

Max nTPM: 120.1
Min nTPM: 88.4
Sample A Male 88.4
Sample B Male 102.6
Sample C Female 120.1
Sample D Female 104.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.1
68410285 Antisense, RP_041214_01_F02, Mouse strain C57BL/6J (56 days, male) 9.2
71015195 Antisense, RP_050725_02_G02, Mouse strain C57BL/6J (56 days, male) 7.1

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