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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
50.9
nTPM
HPA:
36.9
nTPM
GTEx:
50.9
nTPM
FANTOM5:
83.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody CAB033237
Cholangiocytes
Low
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
36.9
Female, age 60
Liver sample 21 nTPM: 36.5
Male, age 54
Liver sample 23 nTPM: 39.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 32.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 18.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 22.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 43.4
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 28.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 40.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 41
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 65.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
50.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 50.9
Samples: 226
Max nTPM: 135.7
Min nTPM: 6.2
Std nTPM: 27.6
Median nTPM: 48.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
135.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
131.3
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
124.1
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
117.0
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
115.5
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
111.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
110.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
108.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
107.4
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
106.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
102.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
102.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
101.4
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
101.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
98.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
98.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
97.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
91.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
90.5
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
89.9
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
88.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
86.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
84.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
84.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
84.5
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
83.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
83.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
83.1
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
82.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
82.4
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
81.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
80.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
80.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
78.5
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
78.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
78.2
GTEX-14PHX-0526-SM-664NW
50-59 years, male
77.1
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
76.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
76.2
GTEX-11ZUS-2526-SM-59872
30-39 years, male
76.1
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
75.2
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
75.0
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
74.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
73.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
73.9
GTEX-QESD-2026-SM-447BI
20-29 years, male
73.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
73.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
72.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
71.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
71.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
71.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
70.9
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
70.9
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
70.6
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
70.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
70.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
69.7
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
69.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
69.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
69.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
69.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
68.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
68.3
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
68.0
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
68.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
67.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
67.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
66.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
64.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
64.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
64.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
64.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
63.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
62.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
62.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
61.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
61.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
61.3
GTEX-11GSP-0626-SM-5986T
60-69 years, female
60.4
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
60.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
59.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
59.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
59.1
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
58.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
58.5
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
58.1
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
58.0
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
57.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
57.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
57.1
GTEX-X261-1726-SM-4PQYT
50-59 years, male
55.7
GTEX-18A7A-1526-SM-72D69
50-59 years, female
55.6
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
55.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
55.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
54.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
54.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
53.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
52.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
52.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
52.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
52.0
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
51.9
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
51.6
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
51.3
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
50.9
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
50.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
50.4
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
49.5
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
49.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
49.3
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
49.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
49.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
48.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
48.5
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
47.8
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
47.3
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
47.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
47.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
46.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
45.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
45.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
45.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
45.3
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
45.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
44.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
43.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
43.2
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
42.9
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
42.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
42.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
42.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
42.5
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
42.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
42.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
42.0
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
41.8
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
41.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
41.6
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
41.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
40.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
40.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
40.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
40.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
39.7
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
39.7
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
39.3
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
39.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
38.7
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
37.9
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
37.9
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
37.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
36.5
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
35.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
35.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
35.6
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
35.2
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
34.2
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
33.8
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
32.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
32.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
32.4
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
31.0
GTEX-18A66-2026-SM-7189C
60-69 years, male
30.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
30.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
29.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
29.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
28.6
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
28.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
28.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
28.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
28.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
28.0
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
27.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
27.8
GTEX-S33H-1626-SM-4AD68
30-39 years, male
27.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
26.7
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
25.1
GTEX-Q734-0326-SM-48U15
40-49 years, female
25.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
24.4
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
23.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
23.0
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
22.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
22.7
GTEX-QEL4-1226-SM-447A4
50-59 years, male
22.6
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
22.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
22.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
22.4
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
22.0
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
22.0
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
21.9
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
21.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
21.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
21.4
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
20.9
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
20.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
20.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
19.7
GTEX-1B932-1426-SM-793AN
40-49 years, female
19.7
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
18.8
GTEX-14PJO-1726-SM-68719
60-69 years, male
18.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
18.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
17.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
16.7
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
16.6
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
15.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
14.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
14.0
GTEX-O5YV-0726-SM-EV798
60-69 years, female
13.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
12.7
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
12.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
11.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
11.5
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
11.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
10.9
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
10.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
10.4
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
10.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
9.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
9.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
9.3
GTEX-S32W-1926-SM-4AD63
50-59 years, female
8.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
8.0
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
7.8
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
7.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
7.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
6.2
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
