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General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
20
Cytoband
p11.23
Chromosome location (bp)
18137228 - 18188387
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle....show less
Gene summary (Entrez)i
Useful information about the gene from Entrez
CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The Splice variant identifier links to the Ensembl website protein summary for the selected splice variant. The data in the Swissprot and TrEMBL columns links to corresponding pages in the UniProt database.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide and number of predicted transmembrane region(s) according to in-house majority decision methods based on sets of predictors are also reported.
Q9H8E8 [Direct mapping] Cysteine-rich protein 2-binding protein
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A0A075B6H4 [Direct mapping] Cysteine-rich protein 2-binding protein
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0004402[histone acetyltransferase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005737[cytoplasm] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0016407[acetyltransferase activity] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0030274[LIM domain binding] GO:0031063[regulation of histone deacetylation] GO:0043966[histone H3 acetylation] GO:0044154[histone H3-K14 acetylation] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0072686[mitotic spindle] GO:0090043[regulation of tubulin deacetylation] GO:0140672[ATAC complex]
Q9H8E8 [Direct mapping] Cysteine-rich protein 2-binding protein
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004402[histone acetyltransferase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005737[cytoplasm] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0016407[acetyltransferase activity] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0030274[LIM domain binding] GO:0031063[regulation of histone deacetylation] GO:0043966[histone H3 acetylation] GO:0044154[histone H3-K14 acetylation] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0072686[mitotic spindle] GO:0090043[regulation of tubulin deacetylation] GO:0140672[ATAC complex]
Q9H8E8 [Direct mapping] Cysteine-rich protein 2-binding protein
Show all
D6RAU4 [Direct mapping] Cysteine-rich protein 2-binding protein
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0004402[histone acetyltransferase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005737[cytoplasm] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0016407[acetyltransferase activity] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0030274[LIM domain binding] GO:0031063[regulation of histone deacetylation] GO:0043966[histone H3 acetylation] GO:0044154[histone H3-K14 acetylation] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0072686[mitotic spindle] GO:0090043[regulation of tubulin deacetylation] GO:0140672[ATAC complex]
Q9H8E8 [Direct mapping] Cysteine-rich protein 2-binding protein
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SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0004402[histone acetyltransferase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005737[cytoplasm] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0016407[acetyltransferase activity] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0030274[LIM domain binding] GO:0031063[regulation of histone deacetylation] GO:0043966[histone H3 acetylation] GO:0044154[histone H3-K14 acetylation] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0072686[mitotic spindle] GO:0090043[regulation of tubulin deacetylation] GO:0140672[ATAC complex]
Q9H8E8 [Direct mapping] Cysteine-rich protein 2-binding protein
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004402[histone acetyltransferase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005737[cytoplasm] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0016407[acetyltransferase activity] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0030274[LIM domain binding] GO:0031063[regulation of histone deacetylation] GO:0043966[histone H3 acetylation] GO:0044154[histone H3-K14 acetylation] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0072686[mitotic spindle] GO:0090043[regulation of tubulin deacetylation] GO:0140672[ATAC complex]
Q9H8E8 [Direct mapping] Cysteine-rich protein 2-binding protein
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004402[histone acetyltransferase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005737[cytoplasm] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0016407[acetyltransferase activity] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0030274[LIM domain binding] GO:0031063[regulation of histone deacetylation] GO:0043966[histone H3 acetylation] GO:0044154[histone H3-K14 acetylation] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0072686[mitotic spindle] GO:0090043[regulation of tubulin deacetylation] GO:0140672[ATAC complex]
Q9H8E8 [Direct mapping] Cysteine-rich protein 2-binding protein
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004402[histone acetyltransferase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005737[cytoplasm] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0016407[acetyltransferase activity] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0030274[LIM domain binding] GO:0031063[regulation of histone deacetylation] GO:0043966[histone H3 acetylation] GO:0044154[histone H3-K14 acetylation] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0072686[mitotic spindle] GO:0090043[regulation of tubulin deacetylation] GO:0140672[ATAC complex]
Q9H8E8 [Direct mapping] Cysteine-rich protein 2-binding protein
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004402[histone acetyltransferase activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005737[cytoplasm] GO:0006355[regulation of DNA-templated transcription] GO:0006357[regulation of transcription by RNA polymerase II] GO:0016407[acetyltransferase activity] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0030274[LIM domain binding] GO:0031063[regulation of histone deacetylation] GO:0043966[histone H3 acetylation] GO:0044154[histone H3-K14 acetylation] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0072686[mitotic spindle] GO:0090043[regulation of tubulin deacetylation] GO:0140672[ATAC complex]
A0A075B6H4 [Direct mapping] Cysteine-rich protein 2-binding protein
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Protein evidence (Ezkurdia et al 2014)
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GO:0000086[G2/M transition of mitotic cell cycle] GO:0005634[nucleus] GO:0016407[acetyltransferase activity] GO:0016573[histone acetylation] GO:0016747[acyltransferase activity, transferring groups other than amino-acyl groups] GO:0045995[regulation of embryonic development] GO:0051302[regulation of cell division] GO:0051726[regulation of cell cycle] GO:0140672[ATAC complex]
The Human Protein Atlas project is funded
