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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
84.3
nTPM
HPA:
83.4
nTPM
GTEx:
84.3
nTPM
FANTOM5:
104.2
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA030691
Cholangiocytes
Not detected
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
83.4
Female, age 60
Liver sample 21 nTPM: 70.9
Male, age 54
Liver sample 23 nTPM: 69.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 152.5
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 33.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 30.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 98.4
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 134.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 114.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 40.5
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 89.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
84.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 84.3
Samples: 226
Max nTPM: 418.8
Min nTPM: 7.3
Std nTPM: 63.3
Median nTPM: 65.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
418.8
GTEX-18A66-2026-SM-7189C
60-69 years, male
386.6
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
300.6
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
276.1
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
221.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
217.2
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
215.6
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
211.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
210.8
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
208.7
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
205.2
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
197.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
192.4
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
184.3
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
182.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
181.2
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
179.8
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
179.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
178.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
176.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
176.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
174.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
171.1
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
169.8
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
169.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
158.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
156.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
155.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
154.3
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
153.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
153.2
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
149.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
149.2
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
148.1
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
145.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
144.6
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
142.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
142.7
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
139.9
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
139.7
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
139.1
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
138.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
138.0
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
131.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
128.5
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
127.6
GTEX-1399T-0826-SM-5IFES
60-69 years, male
125.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
124.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
123.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
123.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
123.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
118.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
116.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
116.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
115.4
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
114.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
114.0
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
113.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
113.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
113.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
111.3
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
108.4
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
107.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
107.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
107.1
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
106.6
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
106.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
106.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
104.8
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
104.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
103.9
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
103.2
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
102.3
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
100.6
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
99.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
99.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
98.6
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
95.6
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
95.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
95.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
94.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
94.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
92.5
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
92.4
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
91.0
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
90.9
GTEX-13112-1426-SM-5EGH8
50-59 years, male
89.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
88.6
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
88.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
88.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
88.0
GTEX-REY6-1226-SM-48FDR
60-69 years, male
87.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
82.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
82.5
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
80.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
79.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
79.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
73.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
73.6
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
73.6
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
73.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
72.7
GTEX-YECK-1926-SM-4W21H
60-69 years, male
72.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
71.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
70.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
69.6
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
68.9
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
68.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
67.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
66.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
66.4
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
66.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
65.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
65.0
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
64.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
64.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
64.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
63.9
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
63.7
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
63.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
63.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
62.7
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
62.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
62.3
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
62.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
61.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
61.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
61.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
60.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
60.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
59.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
59.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
58.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
56.8
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
55.1
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
53.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
53.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
52.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
50.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
50.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
50.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
49.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
49.3
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
49.2
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
49.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
48.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
47.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
47.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
46.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
46.6
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
45.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
44.6
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
44.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
44.1
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
44.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
43.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
43.2
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
42.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
42.6
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
42.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
41.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
40.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
39.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
39.6
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
39.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
39.0
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
38.9
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
38.8
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
36.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
36.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
36.4
GTEX-12696-0826-SM-5EGGE
60-69 years, male
35.4
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
35.3
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
35.3
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
35.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
34.0
GTEX-O5YV-0726-SM-EV798
60-69 years, female
32.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
31.6
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
31.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
31.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
30.4
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
30.3
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
30.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
29.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
29.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
28.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
28.5
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
28.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
28.1
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
28.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
28.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
27.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
27.6
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
27.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
27.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
26.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
26.6
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
26.5
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
25.5
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
25.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
24.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
24.3
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
23.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
22.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
21.6
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
21.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
21.2
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
21.1
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
20.4
GTEX-QEL4-1226-SM-447A4
50-59 years, male
19.9
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
19.9
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
19.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
19.0
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
18.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
18.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
17.8
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
15.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
15.1
GTEX-14XAO-0226-SM-68728
60-69 years, female
15.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
14.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
14.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
13.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
13.3
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
11.2
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
9.6
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
7.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
