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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
18.0
nTPM
HPA:
18.0
nTPM
GTEx:
10.4
nTPM
FANTOM5:
35.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA068771
Cholangiocytes
Low
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
18.0
Female, age 60
Liver sample 21 nTPM: 15.4
Male, age 54
Liver sample 23 nTPM: 19.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 19.5
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 24.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 24.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 13.4
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 23.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 13.4
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 10.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 15.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
10.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 10.4
Samples: 226
Max nTPM: 27.3
Min nTPM: 5.6
Std nTPM: 3.3
Median nTPM: 9.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
27.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
23.3
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
22.3
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
20.2
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
19.0
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
18.2
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
18.2
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
18.0
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
18.0
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
17.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
17.6
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
17.6
GTEX-1B932-1426-SM-793AN
40-49 years, female
16.8
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
16.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
16.6
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
16.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
15.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
15.5
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
15.5
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
15.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
15.4
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
15.1
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
14.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
14.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
14.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
14.7
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
14.3
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
14.2
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
14.1
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
14.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
13.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
13.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
13.7
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
13.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
13.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
13.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
13.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
13.3
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
13.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
13.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
12.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
12.9
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
12.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
12.8
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
12.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
12.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
12.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
12.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
12.3
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
12.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
12.3
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
12.2
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
12.1
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
12.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
12.0
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
11.9
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
11.9
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
11.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
11.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
11.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
11.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
11.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
11.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
11.5
GTEX-RU72-1426-SM-46MUF
50-59 years, female
11.5
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
11.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
11.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
11.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
11.4
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
11.3
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
11.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
11.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
11.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
11.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
11.2
GTEX-S33H-1626-SM-4AD68
30-39 years, male
11.2
GTEX-14PHX-0526-SM-664NW
50-59 years, male
11.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
11.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
11.0
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
10.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
10.9
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
10.9
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
10.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
10.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
10.6
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
10.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
10.5
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
10.5
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
10.4
GTEX-18A66-2026-SM-7189C
60-69 years, male
10.4
GTEX-QEL4-1226-SM-447A4
50-59 years, male
10.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
10.4
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
10.3
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
10.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
10.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
10.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
10.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
10.1
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
10.1
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
10.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
10.0
GTEX-Q734-0326-SM-48U15
40-49 years, female
10.0
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
10.0
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
9.9
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
9.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
9.9
GTEX-1399T-0826-SM-5IFES
60-69 years, male
9.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
9.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
9.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
9.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
9.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
9.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
9.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
9.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
9.6
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
9.6
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
9.6
GTEX-17HHE-0126-SM-79398
50-59 years, male
9.6
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
9.6
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
9.5
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
9.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
9.4
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
9.4
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
9.3
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
9.3
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
9.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
9.3
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
9.3
GTEX-14XAO-0226-SM-68728
60-69 years, female
9.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
9.3
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
9.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
9.3
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
9.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
9.2
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
9.2
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
9.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
9.1
GTEX-S32W-1926-SM-4AD63
50-59 years, female
9.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
9.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
9.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
9.0
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
9.0
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
9.0
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
8.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
8.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
8.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
8.8
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
8.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
8.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
8.7
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
8.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
8.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
8.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
8.5
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
8.5
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
8.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
8.4
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
8.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
8.4
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
8.3
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
8.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
8.2
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
8.2
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
8.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
8.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
8.2
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
8.1
GTEX-14PJO-1726-SM-68719
60-69 years, male
8.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
8.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
8.1
GTEX-11ZUS-2526-SM-59872
30-39 years, male
8.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
8.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
8.0
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
8.0
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
7.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
7.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
7.8
GTEX-R53T-0326-SM-48FEC
50-59 years, female
7.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
7.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
7.8
GTEX-14JG1-1626-SM-664NH
40-49 years, male
7.7
GTEX-P78B-1326-SM-3P611
40-49 years, female
7.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
7.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
7.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
7.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
7.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
7.6
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
7.5
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
7.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
7.4
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
7.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
7.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
7.4
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
7.4
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
7.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
7.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
7.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
7.2
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
7.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
7.1
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
7.1
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
7.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
7.1
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
7.0
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
6.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
6.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
6.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
6.7
GTEX-12696-0826-SM-5EGGE
60-69 years, male
6.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
6.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
6.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
6.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
6.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
6.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
6.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
6.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
6.5
GTEX-QESD-2026-SM-447BI
20-29 years, male
6.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
6.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
6.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
6.3
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
6.1
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
6.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
6.0
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
5.9
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
5.6
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
