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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:69.8 nTPM
HPA Brain:115.9 nTPM
GTEx:69.8 nTPM
FANTOM5:157.1 Scaled Tags Per Million
Pig:187.1 nTPM
Mouse:514.8 nTPM
Allen mouse:15.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

115.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 85.5
2411 Female, age 72, unknown 113.6
2019 Male, age 18, unknown 103.6
1827 Male, age 72, unknown 94.3
1870 Female, age 42, unknown 90.1
2219 Male, age 76, both hemispheres 82.0
1833 Male, age 53, unknown 77.7
2586 Male, age 75, left hemisphere 76.1
1830 Male, age 51, unknown 75.3
2666 Male, age 74, left hemisphere 73.3
2828 Female, age 72, unknown 68.6
Dorsal raphe nucleus
nTPM: 94.0
2298 Female, age 72, unknown 120.1
2750 Male, age 76, both hemispheres 113.3
2047 Male, age 72, unknown 81.0
2016 Female, age 72, unknown 78.0
1828 Male, age 53, unknown 77.4
Inferior colliculus
nTPM: 76.8
2097 Female, age 72, unknown 109.2
1890 Male, age 53, unknown 78.6
1848 Female, age 42, unknown 65.0
2849 Male, age 72, unknown 54.2
Median raphe nucleus
nTPM: 115.9
2220 Male, age 76, midline 115.9
Periaquaductal grey, anterior
nTPM: 99.4
2502 Female, age 75, unknown 104.6
1947 Male, age 18, unknown 100.6
1795 Male, age 51, unknown 93.1
Periaquaductal grey, dorsal
nTPM: 81.2
1831 Male, age 72, unknown 90.7
2464 Female, age 72, unknown 80.0
1840 Male, age 53, unknown 78.2
2850 Male, age 76, both hemispheres 75.9
Periaquaductal grey, lateral
nTPM: 72.3
2272 Male, age 74, both hemispheres 82.4
2053 Male, age 18, unknown 77.9
2140 Male, age 76, both hemispheres 56.7
Pretectal area
nTPM: 103.5
1944 Female, age 72, unknown 138.4
1816 Male, age 51, unknown 135.5
2007 Male, age 72, unknown 128.0
1817 Female, age 42, unknown 125.5
1815 Male, age 53, unknown 117.8
2224 Female, age 72, unknown 103.2
2667 Female, age 75, unknown 93.1
2273 Male, age 74, both hemispheres 91.5
2825 Male, age 18, unknown 74.0
2407 Male, age 75, both hemispheres 67.3
2316 Male, age 76, right hemisphere 63.8
Red nucleus
nTPM: 87.3
1821 Female, age 72, unknown 117.2
1954 Female, age 42, unknown 95.3
1904 Male, age 53, unknown 94.3
2725 Female, age 75, unknown 88.0
2503 Female, age 72, unknown 87.7
1865 Male, age 51, unknown 86.8
2785 Male, age 18, unknown 86.4
2584 Male, age 75, left hemisphere 80.5
2227 Male, age 72, unknown 80.0
2769 Male, age 72, unknown 79.8
2823 Male, age 76, right hemisphere 78.5
2588 Male, age 74, left hemisphere 73.5
Substantia nigra
nTPM: 110.1
2241 Male, age 72, unknown 152.8
2409 Female, age 72, unknown 130.0
1916 Female, age 42, unknown 126.1
1889 Female, age 72, unknown 122.3
1941 Male, age 53, unknown 119.0
1851 Male, age 51, unknown 111.0
2583 Male, age 75, right hemisphere 88.6
2699 Male, age 18, unknown 85.9
2590 Female, age 75, unknown 85.2
2665 Male, age 74, both hemispheres 80.1
Superior colliculus
nTPM: 85.6
2087 Female, age 72, unknown 111.9
2668 Female, age 75, unknown 106.9
2261 Male, age 18, unknown 105.6
2587 Male, age 74, left hemisphere 84.3
1796 Male, age 53, unknown 83.4
1913 Female, age 42, unknown 82.0
1839 Male, age 51, unknown 71.8
2664 Male, age 75, both hemispheres 71.1
1895 Male, age 76, right hemisphere 70.8
1995 Male, age 72, unknown 67.7
Ventral tegmental area
nTPM: 103.9
2410 Female, age 72, unknown 122.3
2218 Male, age 76, both hemispheres 113.4
1942 Male, age 51, unknown 103.5
1915 Female, age 42, unknown 101.6
2021 Male, age 53, unknown 93.1
2223 Female, age 72, unknown 89.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

69.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 69.8
Samples: 139

Max nTPM: 175.8
Min nTPM: 2.6
Std nTPM: 30.6
Median nTPM: 65.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 175.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 156.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 150.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 149.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 136.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 127.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 126.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 125.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 125.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 123.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 120.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 113.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 111.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 109.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 107.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 107.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 104.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 103.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 102.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 100.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 99.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 99.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 96.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 95.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 95.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 95.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 93.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 92.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 92.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 91.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 89.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 89.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 87.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 86.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 85.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 83.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 83.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 82.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 82.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 81.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 81.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 81.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 80.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 78.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 78.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 78.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 78.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 77.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 77.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 77.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 76.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 75.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 74.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 74.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 73.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 73.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 73.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 73.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 72.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 72.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 71.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 71.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 71.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 70.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 68.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 67.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 66.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 66.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 65.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 65.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 64.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 63.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 63.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 63.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 62.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 62.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 61.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 61.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 61.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 61.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 60.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 60.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 60.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 60.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 59.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 59.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 59.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 59.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 58.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 57.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 57.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 57.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 56.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 56.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 56.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 56.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 55.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 55.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 55.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 54.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 54.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 52.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 52.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 51.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 50.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 50.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 48.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 47.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 46.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 46.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 46.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 45.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 45.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 44.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 44.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 43.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 43.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 43.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 38.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 37.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 36.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 36.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 36.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 35.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 35.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 35.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 32.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 29.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 27.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 27.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 24.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 20.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 20.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 19.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 18.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 16.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 16.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 13.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 2.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

157.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 157.1
FF:10158-103A5 76 years, female 157.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

187.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 162.6
Samples: 4

Max nTPM: 230.9
Min nTPM: 95.7
Sample A Female 230.9
Sample B Female 126.7
Sample C Male 197.1
Sample D Male 95.7
Midbrain
nTPM: 185.8
Samples: 4

Max nTPM: 232.9
Min nTPM: 144.2
Sample A Female 144.2
Sample B Female 174.8
Sample C Male 232.9
Sample D Male 191.2
Periaqueductal gray
nTPM: 139.4
Samples: 3

Max nTPM: 156.3
Min nTPM: 126.3
Sample B Female 126.3
Sample C Male 156.3
Sample D Male 135.5
Superior colliculi
nTPM: 187.1
Samples: 4

Max nTPM: 236.5
Min nTPM: 114.3
Sample A Female 215.1
Sample B Female 114.3
Sample C Male 236.5
Sample D Male 182.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

514.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 514.8
Samples: 4

Max nTPM: 531.2
Min nTPM: 501.3
Sample A Male 504.7
Sample B Male 521.9
Sample C Female 501.3
Sample D Female 531.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.7
583562 Antisense, RP_040831_02_H12, Mouse strain C57BL/6J (56 days, male) 19.4
81599674 Antisense, RP_071219_04_H02, Mouse strain C57BL/6J (56 days, male) 11.9

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