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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:87.7 nTPM
HPA Brain:138.8 nTPM
GTEx:87.7 nTPM
FANTOM5:22.4 Scaled Tags Per Million
Pig:658.6 nTPM
Mouse:453.1 nTPM
Allen mouse:21.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

138.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 95.1
2219 Male, age 76, both hemispheres 149.5
2666 Male, age 74, left hemisphere 137.6
1870 Female, age 42, unknown 93.1
1827 Male, age 72, unknown 92.3
2828 Female, age 72, unknown 91.1
2019 Male, age 18, unknown 90.7
2586 Male, age 75, left hemisphere 83.3
1833 Male, age 53, unknown 75.0
2411 Female, age 72, unknown 72.4
1830 Male, age 51, unknown 65.9
Dorsal raphe nucleus
nTPM: 81.8
2047 Male, age 72, unknown 95.0
1828 Male, age 53, unknown 92.2
2750 Male, age 76, both hemispheres 88.9
2298 Female, age 72, unknown 88.2
2016 Female, age 72, unknown 44.5
Inferior colliculus
nTPM: 97.7
1848 Female, age 42, unknown 109.4
2849 Male, age 72, unknown 102.7
1890 Male, age 53, unknown 89.8
2097 Female, age 72, unknown 88.8
Median raphe nucleus
nTPM: 138.8
2220 Male, age 76, midline 138.8
Periaquaductal grey, anterior
nTPM: 137.2
2502 Female, age 75, unknown 144.0
1947 Male, age 18, unknown 139.4
1795 Male, age 51, unknown 128.3
Periaquaductal grey, dorsal
nTPM: 86.5
2850 Male, age 76, both hemispheres 101.6
1831 Male, age 72, unknown 96.9
1840 Male, age 53, unknown 86.9
2464 Female, age 72, unknown 60.7
Periaquaductal grey, lateral
nTPM: 73.8
2140 Male, age 76, both hemispheres 78.2
2272 Male, age 74, both hemispheres 71.6
2053 Male, age 18, unknown 71.5
Pretectal area
nTPM: 123.7
2667 Female, age 75, unknown 202.2
1817 Female, age 42, unknown 179.0
1944 Female, age 72, unknown 178.8
1816 Male, age 51, unknown 169.4
2007 Male, age 72, unknown 155.9
1815 Male, age 53, unknown 117.9
2224 Female, age 72, unknown 88.4
2825 Male, age 18, unknown 77.0
2407 Male, age 75, both hemispheres 72.3
2316 Male, age 76, right hemisphere 61.2
2273 Male, age 74, both hemispheres 58.8
Red nucleus
nTPM: 66.2
2785 Male, age 18, unknown 105.6
1865 Male, age 51, unknown 72.6
1821 Female, age 72, unknown 70.2
2588 Male, age 74, left hemisphere 70.2
2584 Male, age 75, left hemisphere 69.6
2227 Male, age 72, unknown 64.6
2769 Male, age 72, unknown 63.3
1954 Female, age 42, unknown 61.3
2823 Male, age 76, right hemisphere 56.2
1904 Male, age 53, unknown 55.4
2725 Female, age 75, unknown 52.8
2503 Female, age 72, unknown 52.3
Substantia nigra
nTPM: 119.7
2665 Male, age 74, both hemispheres 202.6
1889 Female, age 72, unknown 173.1
1941 Male, age 53, unknown 159.8
1916 Female, age 42, unknown 159.3
1851 Male, age 51, unknown 123.0
2241 Male, age 72, unknown 95.0
2699 Male, age 18, unknown 92.7
2409 Female, age 72, unknown 88.6
2590 Female, age 75, unknown 55.1
2583 Male, age 75, right hemisphere 47.6
Superior colliculus
nTPM: 95.0
1895 Male, age 76, right hemisphere 133.3
2087 Female, age 72, unknown 119.8
1796 Male, age 53, unknown 117.6
2668 Female, age 75, unknown 117.0
2261 Male, age 18, unknown 99.2
2664 Male, age 75, both hemispheres 82.0
1839 Male, age 51, unknown 77.6
2587 Male, age 74, left hemisphere 75.1
1913 Female, age 42, unknown 74.8
1995 Male, age 72, unknown 53.5
Ventral tegmental area
nTPM: 108.8
2218 Male, age 76, both hemispheres 188.0
2410 Female, age 72, unknown 109.6
1915 Female, age 42, unknown 103.5
1942 Male, age 51, unknown 95.4
2223 Female, age 72, unknown 88.3
2021 Male, age 53, unknown 67.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

87.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 87.7
Samples: 139

Max nTPM: 392.6
Min nTPM: 6.2
Std nTPM: 69.2
Median nTPM: 72.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 392.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 366.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 271.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 236.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 227.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 215.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 214.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 186.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 186.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 183.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 177.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 173.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 172.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 170.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 168.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 166.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 166.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 166.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 165.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 165.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 165.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 164.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 164.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 160.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 158.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 153.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 150.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 146.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 139.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 139.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 132.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 132.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 132.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 126.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 125.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 124.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 123.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 122.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 121.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 120.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 120.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 119.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 118.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 116.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 112.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 111.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 109.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 106.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 105.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 105.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 104.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 104.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 100.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 95.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 94.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 93.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 90.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 90.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 89.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 89.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 88.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 86.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 85.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 84.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 83.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 81.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 78.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 73.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 72.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 72.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 71.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 68.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 67.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 67.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 64.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 63.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 62.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 62.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 62.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 60.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 54.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 54.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 53.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 52.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 50.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 49.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 48.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 48.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 47.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 46.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 43.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 42.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 42.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 42.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 42.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 39.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 39.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 37.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 36.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 35.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 34.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 33.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 33.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 32.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 31.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 31.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 31.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 29.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 28.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 27.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 26.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 26.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 25.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 22.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 22.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 22.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 21.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 20.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 19.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 18.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 17.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 16.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 16.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 16.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 15.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 15.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 14.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 13.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 13.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 13.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 12.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 12.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 11.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 11.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 9.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 8.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 7.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 6.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 6.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

22.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 22.4
FF:10158-103A5 76 years, female 22.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

658.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 464.8
Samples: 4

Max nTPM: 678.9
Min nTPM: 164.8
Sample A Female 675.2
Sample B Female 340.3
Sample C Male 678.9
Sample D Male 164.8
Midbrain
nTPM: 559.8
Samples: 4

Max nTPM: 1058.2
Min nTPM: 192.3
Sample A Female 192.3
Sample B Female 340.6
Sample C Male 1058.2
Sample D Male 648.0
Periaqueductal gray
nTPM: 355.1
Samples: 3

Max nTPM: 475.3
Min nTPM: 277.1
Sample B Female 277.1
Sample C Male 475.3
Sample D Male 312.9
Superior colliculi
nTPM: 658.7
Samples: 4

Max nTPM: 900.2
Min nTPM: 398.2
Sample A Female 707.3
Sample B Female 398.2
Sample C Male 900.2
Sample D Male 628.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

453.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 453.1
Samples: 4

Max nTPM: 468.3
Min nTPM: 437.5
Sample A Male 437.5
Sample B Male 443.7
Sample C Female 468.3
Sample D Female 463.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

21.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 21.9
68798025 Antisense, RP_050215_01_F04, Mouse strain C57BL/6J (56 days, male) 21.9

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