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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
78.4
nTPM
HPA:
45.2
nTPM
GTEx:
78.4
nTPM
FANTOM5:
109.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA026545
Cholangiocytes
Medium
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
45.2
Female, age 60
Liver sample 21 nTPM: 93.1
Male, age 54
Liver sample 23 nTPM: 8.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 49.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 32.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 18.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 42.2
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 18.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 78.5
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 35.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 76
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
78.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 78.4
Samples: 226
Max nTPM: 401.2
Min nTPM: 3.1
Std nTPM: 60.1
Median nTPM: 65.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
401.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
267.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
262.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
260.3
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
227.7
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
218.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
218.5
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
213.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
212.1
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
205.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
201.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
196.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
191.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
187.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
185.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
182.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
180.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
179.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
174.5
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
171.6
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
164.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
159.1
GTEX-RU72-1426-SM-46MUF
50-59 years, female
154.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
153.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
151.5
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
150.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
149.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
148.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
146.5
GTEX-18465-1626-SM-7LG6N
50-59 years, male
145.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
141.6
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
139.2
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
134.1
GTEX-17HHE-0126-SM-79398
50-59 years, male
132.3
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
131.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
130.2
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
128.1
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
126.4
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
126.2
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
124.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
123.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
123.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
121.7
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
121.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
121.2
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
121.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
118.1
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
118.0
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
117.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
116.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
114.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
113.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
113.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
110.5
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
110.3
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
108.7
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
108.3
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
108.2
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
107.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
107.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
107.2
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
105.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
105.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
105.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
103.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
103.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
102.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
101.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
99.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
97.2
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
96.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
95.7
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
95.6
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
95.3
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
95.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
94.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
93.8
GTEX-1B933-1226-SM-731DW
50-59 years, female
91.8
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
90.9
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
90.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
90.1
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
90.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
88.5
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
88.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
86.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
85.0
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
84.9
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
82.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
80.5
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
79.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
77.1
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
77.0
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
76.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
76.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
75.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
74.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
74.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
73.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
72.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
71.1
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
70.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
70.4
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
70.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
69.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
68.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
67.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
67.2
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
66.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
66.6
GTEX-14JG1-1626-SM-664NH
40-49 years, male
66.4
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
66.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
65.8
GTEX-18A66-2026-SM-7189C
60-69 years, male
65.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
65.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
65.0
GTEX-S32W-1926-SM-4AD63
50-59 years, female
63.0
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
62.6
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
61.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
59.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
59.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
58.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
58.4
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
57.6
GTEX-QEL4-1226-SM-447A4
50-59 years, male
57.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
56.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
55.6
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
55.4
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
53.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
52.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
52.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
52.0
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
50.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
50.9
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
50.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
50.0
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
49.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
49.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
48.5
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
48.4
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
48.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
48.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
47.9
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
47.4
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
47.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
46.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
45.9
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
45.6
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
45.6
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
44.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
43.3
GTEX-14XAO-0226-SM-68728
60-69 years, female
43.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
42.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
41.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
41.8
GTEX-13113-1326-SM-5GCOI
60-69 years, female
40.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
40.6
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
40.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
39.7
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
39.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
39.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
39.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
38.5
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
38.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
37.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
37.2
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
36.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
35.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
34.4
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
33.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
33.3
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
33.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
31.9
GTEX-QESD-2026-SM-447BI
20-29 years, male
31.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
31.2
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
31.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
31.0
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
30.3
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
29.9
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
29.3
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
28.5
GTEX-REY6-1226-SM-48FDR
60-69 years, male
28.2
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
26.3
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
25.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
25.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
25.1
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
24.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
24.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
24.0
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
23.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
23.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
22.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
22.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
22.2
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
21.7
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
21.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
21.2
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
20.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
19.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
19.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
19.3
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
18.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
18.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
17.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
17.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
17.8
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
17.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
17.2
GTEX-11GSP-0626-SM-5986T
60-69 years, female
15.4
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
14.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
14.3
GTEX-14PHX-0526-SM-664NW
50-59 years, male
12.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
11.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
11.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
11.1
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
9.9
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
9.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
7.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
7.2
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
7.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
5.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
4.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
4.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
4.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
4.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
3.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
3.1
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
